The bifunctional autophagic flux by 2-deoxyglucose to control survival or growth of prostate cancer cells

Tumor aerobic glycolysis: new insights into therapeutic strategies with targeted delivery

(2014) Meghna Talekar et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Knockdown of TIGAR by RNA interference induces apoptosis and autophagy in HepG2 hepatocellular carcinoma cells

(2013) Ling Ye et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Marchantin M: a novel inhibitor of proteasome induces autophagic cell death in prostate cancer cells

(2013) H Jiang et al.   Cell Death & Disease

Aurora kinase A inhibition-induced autophagy triggers drug resistance in breast cancer cells

(2012) Zhengzhi Zou et al.   Autophagy

The Fundamental Role of the p53 Pathway in Tumor Metabolism and Its Implication in Tumor Therapy

(2012) L. Shen et al.   CLINICAL CANCER RESEARCH

Blocked Autophagy Using Lysosomotropic Agents Sensitizes Resistant Prostate Tumor Cells to the Novel Akt Inhibitor AZD5363

(2012) F. Lamoureux et al.   CLINICAL CANCER RESEARCH

Targeting disease through novel pathways of apoptosis and autophagy

(2012) Kenneth Maiese et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Chloroquine or Chloroquine-PI3K/Akt Pathway Inhibitor Combinations Strongly Promote γ-Irradiation-Induced Cell Death in Primary Stem-Like Glioma Cells

(2012) Elke Firat et al.   PLoS One

Effect of dual inhibition of apoptosis and autophagy in prostate cancer

(2012) Ahamed Saleem et al.   PROSTATE

Cancer metabolism: current perspectives and future directions

(2012) C Muñoz-Pinedo et al.   Cell Death & Disease

Regulation of Autophagy by Glucose in Mammalian Cells

(2012) Félix Moruno et al.   Cells

Autophagic cell death: Loch Ness monster or endangered species?

(2011) Han-Ming Shen et al.   Autophagy

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Regulation of the autophagy initiating kinase ULK1 by nutrients: Roles of mTORC1 and AMPK

(2011) Joungmok Kim et al.   CELL CYCLE

Principles and Current Strategies for Targeting Autophagy for Cancer Treatment

(2011) R. K. Amaravadi et al.   CLINICAL CANCER RESEARCH

Metabolism and brain cancer

(2011) Suely Kazue Nagahashi Marie et al.   Clinics

The dynamic nature of autophagy in cancer

(2011) A. C. Kimmelman   GENES & DEVELOPMENT

Dual Inhibition of Tumor Energy Pathway by 2-Deoxyglucose and Metformin Is Effective against a Broad Spectrum of Preclinical Cancer Models

(2011) J.-H. Cheong et al.   MOLECULAR CANCER THERAPEUTICS

p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

(2011) Peng Jiang et al.   NATURE CELL BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

2-Deoxy-d-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion

(2010) Haibin Xi et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

Metabolism and proliferation share common regulatory pathways in cancer cells

(2010) V Fritz et al.   ONCOGENE

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Anti- and pro-tumor functions of autophagy

(2009) Eugenia Morselli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Silencing of Elongation Factor-2 Kinase Potentiates the Effect of 2-Deoxy-D-Glucose against Human Glioma Cells through Blunting of Autophagy

(2009) H. Wu et al.   CANCER RESEARCH

Brick by brick: metabolism and tumor cell growth

(2008) Ralph J DeBerardinis et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Vacuolar and Plasma Membrane Proton Pumps Collaborate to Achieve Cytosolic pH Homeostasis in Yeast

(2008) Gloria A. Martínez-Muñoz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagic Death of Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal

(2008) Seong-Woon Yu et al.   STEM CELLS