Ticagrelor Conditioning Effects Are Not Additive to Cardioprotection Induced by Direct NLRP3 Inflammasome Inhibition: Role of RISK, NLRP3, and Redox Cascades
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Title
Ticagrelor Conditioning Effects Are Not Additive to Cardioprotection Induced by Direct NLRP3 Inflammasome Inhibition: Role of RISK, NLRP3, and Redox Cascades
Authors
Keywords
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Journal
Oxidative Medicine and Cellular Longevity
Volume 2020, Issue -, Pages 1-12
Publisher
Hindawi Limited
Online
2020-08-05
DOI
10.1155/2020/9219825
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Note: Only part of the references are listed.- The NLRP3 Inflammasome Inhibitor, OLT1177 (Dapansutrile), Reduces Infarct Size and Preserves Contractile Function After Ischemia Reperfusion Injury in the Mouse
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- (2015) Ewelina M. Golebiewska et al. BLOOD REVIEWS
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