Novel Methodologies for Chemical Activation in Organic Synthesis under Solvent-Free Reaction Conditions

Dual Mechanoenzymatic Kinetic Resolution of (±)‐Ketorolac

(2020) Mario Pérez‐Venegas et al.   ChemCatChem

Green Asymmetric Organocatalysis

(2020) Domimika Kristofikova et al.   ChemSusChem

Application of Chiral Isocyanides in Multicomponent Reactions

(2020) Vaezeh Fathi Vavsari et al.   CURRENT ORGANIC CHEMISTRY

A Review on Solvent-free Methods in Organic Synthesis

(2020) Sainath Zangade et al.   CURRENT ORGANIC CHEMISTRY

Recent Advances And Perspectives In The Silver-Catalyzed Multi-Component Reactions

(2020) G. S. Susan Treesa et al.   CURRENT ORGANIC CHEMISTRY

Diastereoselectivity in Passerini reactions of chiral aldehydes and in Ugi reactions of chiral cyclic imines

(2020) Chiara Lambruschini et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Green synthesis of bioactive oligopeptides promoted by recyclable nanocrystalline hydroxyapatite

(2020) Michele Anselmi et al.   Future Medicinal Chemistry

Synthesis of Biologically Active Molecules through Multicomponent Reactions

(2020) Daniel Insuasty et al.   MOLECULES

Practical Synthesis of High‐Performance Amino Tf‐Amide Organocatalysts for Asymmetric Aldol Reactions

(2020) Hanbin Lu et al.   Asian Journal of Organic Chemistry

Zinc‐Catalysed Multi‐Component Reactions: An Overview

(2020) Mohan Neetha et al.   ChemistrySelect

Review on the Ugi Multicomponent Reaction Mechanism and the Use of Fluorescent Derivatives as Functional Chromophores

(2020) Rafael O. Rocha et al.   ACS Omega

Synthesis of functionalized oxazolidines by multicomponent reactions of 1,2-amino alcohols (microreview)

(2020) Xianjun Xu et al.   Chemistry of Heterocyclic Compounds

Catalytic Room-Temperature C−N Coupling of Amides and Isocyanates by Using Mechanochemistry

(2020) Gandrath Dayaker et al.   ChemSusChem

Recent Advances in Microwave Assisted Multicomponent Reactions

(2020) Jaleel Fairoosa et al.   ChemistrySelect

Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst

(2020) Mahmoud Abd El Aleem Ali Ali El-Remaily et al.   ACS Omega

Mechanochemical and Mechanoenzymatic Synthesis of Pharmacologically Active Compounds: A Green Perspective

(2020) Mario Pérez-Venegas et al.   ACS Sustainable Chemistry & Engineering

Heterogeneous Photocatalysis in Organic Synthesis

(2020) Sebastian Gisbertz et al.   ChemPhotoChem

A multi-substrate screening approach for the identification of a broadly applicable Diels–Alder catalyst

(2019) Hyejin Kim et al.   Nature Communications

The Pharmaceutical Industry in 2018. An Analysis of FDA Drug Approvals from the Perspective of Molecules

(2019) Beatriz G. de la Torre et al.   MOLECULES

Sustainability Challenges in Peptide Synthesis and Purification: From R&D to Production

(2019) Albert Isidro-Llobet et al.   JOURNAL OF ORGANIC CHEMISTRY

Making Solid-Phase Peptide Synthesis Greener: A Review of the Literature

(2019) Kyriakos G. Varnava et al.   Chemistry-An Asian Journal

Mechanical activation drastically accelerates amide bond hydrolysis, matching enzyme activity

(2019) Michael F Pill et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Continuous biocatalysis in environmentally‐friendly media: A triple synergy for future sustainable processes.

(2019) Nadia Veronica Guajardo et al.   ChemCatChem

Broadening the Scope of Biocatalysis in Sustainable Organic Synthesis

(2019) Roger A. Sheldon et al.   ChemSusChem

A Green Approach for Organic Transformations Using Microwave Reactor

(2019) Subrata Das et al.   CURRENT ORGANIC SYNTHESIS

A New Wave of Amide Bond Formations for Peptide Synthesis

(2019) Karlijn Hollanders et al.   SYNTHESIS-STUTTGART

Microwave-assisted multicomponent synthesis of julolidines using silica-supported calix[4]arene as heterogeneous catalyst

(2019) Walysson Ferreira de Paiva et al.   TETRAHEDRON

Solvent-free mechanochemical synthesis of diacylfuroxans

(2019) Zhen-Zhen Gu et al.   TETRAHEDRON LETTERS

Deep Eutectic Solvents as Efficient Solvents in Biocatalysis

(2019) Magdalena Pätzold et al.   TRENDS IN BIOTECHNOLOGY

Versatility of Candida antarctica lipase in the amide bond formation applied in organic synthesis and biotechnological processes

(2019) Rafaely N. Lima et al.   Molecular Catalysis

Mechanochemistry for Synthesis

(2019) Tomislav Friscic et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multicomponent reactions in the synthesis of bioactive compounds: a review

(2019) Felipe Vitório et al.   CURRENT ORGANIC SYNTHESIS

Electrochemistry and Photoredox Catalysis: A Comparative Evaluation in Organic Synthesis

(2019) Rik H. Verschueren et al.   MOLECULES

Recent applications of mechanochemistry in enantioselective synthesis

(2019) C. Gabriela Avila-Ortiz et al.   TETRAHEDRON LETTERS

Alternate Energy Sources for Sustainable Organic Synthesis

(2019) Bablee Mandal   ChemistrySelect

Cyclic Tetrapeptides from Nature and Design: A Review of Synthetic Methodologies, Structure, and Function

(2019) Vijayalekshmi Sarojini et al.   CHEMICAL REVIEWS

Selected application of peptide molecules as pharmaceutical agents and in cosmeceuticals

(2019) Manica Negahdaripour et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Optimized Methodologies in Asymmetric Organic Synthesis Applying Microwaves

(2019) Yamir Bandala et al.   Journal of the Mexican Chemical Society

Photoenzymatic Approaches in Organic Synthesis

(2019) Jie Chen et al.   Asian Journal of Organic Chemistry

Umpolung Strategy for α-Functionalization of Aldehydes for the Addition of Thiols and other Nucleophiles

(2019) Jakob Blom et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design of Carbon-carbon and Carbon-heteroatom Bond Formation Reactions under Green Conditions

(2019) Nagaraju Kerru et al.   CURRENT ORGANIC CHEMISTRY

Visible-light-promoted C N and C S bonds formation: A catalyst and solvent-free photochemical approach for the synthesis of 1,3-thiazolidin-4-ones

(2019) Mohd Nazeef et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

Design and preparation of a novel prolinamide-based organocatalyst for the solvent-free asymmetric aldol reaction

(2019) Rafaela de S. Martins et al.   TETRAHEDRON

Organocatalytic Enantioselective Higher-Order Cycloadditions of In Situ Generated Amino Isobenzofulvenes

(2018) Bjarke S. Donslund et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-Light Photocatalysis: Does It Make a Difference in Organic Synthesis?

(2018) Leyre Marzo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

My Twenty Years in Microwave Chemistry: From Kitchen Ovens to Microwaves that aren't Microwaves

(2018) C. Oliver Kappe   CHEMICAL RECORD

From Synthesis of Amino Acids and Peptides to Enzymatic Catalysis: A Bottom-Up Approach in Mechanochemistry

(2018) Carsten Bolm et al.   ChemSusChem

Organocatalytic Asymmetric Synthesis of Trifluoromethylated Tetrahydrocarbazoles by a Vinylogous Michael/Aldol Formal [4+2] Annulation

(2018) Ehsan Jafari et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Papain-catalysed mechanochemical synthesis of oligopeptides by milling and twin-screw extrusion: application in the Juliá–Colonna enantioselective epoxidation

(2018) Karen J. Ardila-Fierro et al.   GREEN CHEMISTRY

Origins of the Mechanochemical Coupling of Peptide Bond Formation to Protein Synthesis

(2018) Benjamin Fritch et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic synthesis of 3-aminooxindoles via addition to isatin imine: an update

(2018) Jasneet Kaur et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Photoorganocatalysis, small organic molecules and light in the service of organic synthesis: the awakening of a sleeping giant

(2018) Ioanna K. Sideri et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Organocatalytic Oxa-Michael/Michael/Michael/Aldol Condensation Quadruple Domino Sequence: Asymmetric Synthesis of Tricyclic Chromanes

(2018) Mukesh Kumar et al.   ORGANIC LETTERS

Mechanochemical Organic Synthesis: The Art of Making Chemistry Green

(2018) Vjekoslav Štrukil   SYNLETT

Asymmetric Synthesis of Cyclopentene-Fused Tetrahydroquinolines via N-Heterocyclic Carbene Catalyzed Domino Reactions

(2018) Dieter Enders et al.   SYNTHESIS-STUTTGART

Recent examples of the use of biocatalysts with high accessibility and availability in natural product synthesis

(2018) Takeshi Sugai et al.   TETRAHEDRON

Recent advances in mechanochemical C–H functionalization reactions

(2018) Shujuan Zhao et al.   TETRAHEDRON LETTERS

Multicomponent mechanochemical synthesis

(2018) Marco Leonardi et al.   Chemical Science

Promiscuity of Lipase-Catalyzed Reactions for Organic Synthesis: A Recent Update

(2018) Bharat P. Dwivedee et al.   ChemistrySelect

Catalytic Asymmetric [4+2]-Cycloadditions Using Tropolones: Developments, Scope, Transformations, and Bioactivity

(2018) Niels Hammer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-light-activated C–C and C–N bond formation in the synthesis of imidazo[1,2-a]pyridines and imidazo[2,1-b]thiazoles under catalyst and solvent-free conditions

(2018) Km Neha Shivhare et al.   NEW JOURNAL OF CHEMISTRY

Sophalines E–I, Five Quinolizidine-Based Alkaloids with Antiviral Activities against the Hepatitis B Virus from the Seeds of Sophora alopecuroides

(2018) Yu-Bo Zhang et al.   ORGANIC LETTERS

Mechanoenzymatic resolution of racemic chiral amines, a green technique for the synthesis of pharmaceutical building blocks

(2018) Mario Pérez-Venegas et al.   TETRAHEDRON

Visible-Light Photoredox-Catalyzed Thioacetalization of Aldehydes Under Metal-Free and Solvent-Free Conditions

(2018) Kai Du et al.   ADVANCED SYNTHESIS & CATALYSIS

Peptide Synthesis Utilizing Micro-flow Technology

(2018) Shinichiro Fuse et al.   Chemistry-An Asian Journal

Asymmetric Synthesis of 2,2-Disubstituted Benzofuranones through an Organocatalytic Alkylation with Nitroallylic Acetates

(2018) Dieter Enders et al.   SYNTHESIS-STUTTGART

Photosensitization and Photocatalysis—Perspectives in Organic Synthesis

(2018) Clément Michelin et al.   ACS Catalysis

Photocatalysis in Organic Synthesis - Past, Present, and Future

(2017) Burkhard König   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Mechanochemical Synthesis of Dipeptides Using Mg-Al Hydrotalcite as Activating Agent under Solvent-Free Reaction Conditions

(2017) José M. Landeros et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Mechanochemistry for Organic Chemists: An Update

(2017) Davin Tan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Mechanoenzymatic peptide and amide bond formation

(2017) José G. Hernández et al.   GREEN CHEMISTRY

The greening of peptide synthesis

(2017) Stefan B. Lawrenson et al.   GREEN CHEMISTRY

Altering Product Selectivity by Mechanochemistry

(2017) José G. Hernández et al.   JOURNAL OF ORGANIC CHEMISTRY

Microwave-assisted solvent-free synthesis of novel benzoxazines: A faster and environmentally friendly route to the development of bio-based thermosetting resins

(2017) Jéssica R. Oliveira et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Mechanochemical Lignin-Mediated Strecker Reaction

(2017) Saumya Dabral et al.   MOLECULES

Improving the Catalytic Performance of (S)-Proline as Organocatalyst in Asymmetric Aldol Reactions in the Presence of Solvate Ionic Liquids: Involvement of a Supramolecular Aggregate

(2017) Arturo Obregón-Zúñiga et al.   ORGANIC LETTERS

Enantioselective Vinylogous Organocascade Reactions

(2016) Hamish B. Hepburn et al.   CHEMICAL RECORD

Synthesis of julolidine-containing nonlinear optical chromophores: Achieving excellent electro-optic activity by optimizing the bridges and acceptors

(2016) Fenggang Liu et al.   DYES AND PIGMENTS

Peptide Mechanosynthesis by Direct Coupling of N -Protected α-Amino Acids with Amino Esters

(2016) Vincent Porte et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Ugi 4-CR and Passerini 3-CR Adducts under Mechanochemical Activation

(2016) Luis A. Polindara-García et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A decade update on solvent and catalyst-free neat organic reactions: a step forward towards sustainability

(2016) Anirban Sarkar et al.   GREEN CHEMISTRY

α,α-Dicyanoolefins: versatile substrates in organocatalytic asymmetric transformations

(2016) Jasneet Kaur et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Substituted 1,2,3-Triazoles via Metal-Free Click Cycloaddition Reactions and Alternative Cyclization Methods

(2016) Svetlana Tsogoeva et al.   SYNTHESIS-STUTTGART

Asymmetric cycloaddition reactions catalyzed by bifunctional thiourea and squaramide organocatalysts: recent advances

(2016) Felix E. Held et al.   Catalysis Science & Technology

Mechanochemistry: A Force of Synthesis

(2016) Jean-Louis Do et al.   ACS Central Science

The Diarylprolinol Silyl Ethers: Ten Years After

(2015) Bjarke S. Donslund et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic activity of α,α-dipeptide derivatives of (S)-proline in the asymmetric aldol reaction in absence of solvent. Evidence for non-covalent π–π interactions in the transition state

(2015) Elizabeth Machuca et al.   TETRAHEDRON LETTERS

Structural features of N-benzylated-β-amino acid methyl esters essential for enantiodifferentiation by lipase B from Candida antarctica in hydrolytic reactions

(2015) Hiram Rangel et al.   TETRAHEDRON-ASYMMETRY

An efficient mechanochemical synthesis of amides and dipeptides using 2,4,6-trichloro-1,3,5-triazine and PPh3

(2015) Chuthamat Duangkamol et al.   RSC Advances

Synthesis and Evaluation of (S)-Proline-Containing α,β-Dipeptides as Organocatalysts in Solvent-Free Asymmetric Aldol Reactions Under Ball-Milling Conditions

(2014) Elizabeth Machuca et al.   Asian Journal of Organic Chemistry

The historical development of mechanochemistry

(2013) Laszlo Takacs   CHEMICAL SOCIETY REVIEWS

Solvent-Free and Catalysts-Free Chemistry: A Benign Pathway to Sustainability

(2013) Manoj B. Gawande et al.   ChemSusChem

Recent efforts directed to the development of more sustainable asymmetric organocatalysis

(2012) José G. Hernández et al.   CHEMICAL COMMUNICATIONS

Mechanochemistry: opportunities for new and cleaner synthesis

(2011) Stuart L. James et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric Aldol Reaction Organocatalyzed by (S)-Proline-Containing Dipeptides: Improved Stereoinduction under Solvent-Free Conditions

(2011) José G. Hernández et al.   JOURNAL OF ORGANIC CHEMISTRY

Efficient ball-mill procedure in the ‘green’ asymmetric aldol reaction organocatalyzed by (S)-proline-containing dipeptides in the presence of water

(2011) José G. Hernández et al.   TETRAHEDRON

Solvent-free asymmetric aldol reaction organocatalyzed by (S)-proline-containing thiodipeptides under ball-milling conditions

(2011) José G. Hernández et al.   TETRAHEDRON

Applications of biotransformations and biocatalysis to complexity generation in organic synthesis

(2009) Tomas Hudlicky et al.   CHEMICAL SOCIETY REVIEWS

Green Chemistry: Principles and Practice

(2009) Paul Anastas et al.   CHEMICAL SOCIETY REVIEWS

Enzyme engineering for enantioselectivity: from trial-and-error to rational design?

(2009) Linda G. Otten et al.   TRENDS IN BIOTECHNOLOGY

The advent and development of organocatalysis

(2008) David W. C. MacMillan   NATURE