Making Solid-Phase Peptide Synthesis Greener: A Review of the Literature

N-Butylpyrrolidinone as Alternative Solvent for Solid-Phase Peptide Synthesis

(2018) John Lopez et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Automatic procedures for the synthesis of difficult peptides using oxyma as activating reagent: A comparative study on the use of bases and on different deprotection and agitation conditions

(2018) A. Caporale et al.   PEPTIDES

Microwave-Assisted Green Solid-Phase Peptide Synthesis Using γ-Valerolactone (GVL) as Solvent

(2018) Ashish Kumar et al.   ACS Sustainable Chemistry & Engineering

Mechanochemical Synthesis of Dipeptides Using Mg-Al Hydrotalcite as Activating Agent under Solvent-Free Reaction Conditions

(2017) José M. Landeros et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Greener solvents for solid-phase synthesis

(2017) Stefan Lawrenson et al.   GREEN CHEMISTRY

The greening of peptide synthesis

(2017) Stefan B. Lawrenson et al.   GREEN CHEMISTRY

Re-evaluating the stability of COMU in different solvents

(2017) Ashish Kumar et al.   JOURNAL OF PEPTIDE SCIENCE

Antifreeze peptide pretreatment minimizes freeze-thaw damage to cherries: An in-depth investigation

(2017) Charles H.Z. Kong et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Green Solid-Phase Peptide Synthesis (GSPPS) 3. Green Solvents for Fmoc Removal in Peptide Chemistry

(2017) Yahya E. Jad et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Green solid-phase peptide synthesis 4. γ-Valerolactone and N -formylmorpholine as green solvents for solid phase peptide synthesis

(2017) Ashish Kumar et al.   TETRAHEDRON LETTERS

Butelase-Mediated Macrocyclization of d -Amino-Acid-Containing Peptides

(2016) Giang K. T. Nguyen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The road to the synthesis of “difficult peptides”

(2016) Marta Paradís-Bas et al.   CHEMICAL SOCIETY REVIEWS

Antimicrobial peptides (AMPs) as drug candidates: a patent review (2003–2015)

(2016) Paulina Kosikowska et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Butelase-mediated cyclization and ligation of peptides and proteins

(2016) Giang K T Nguyen et al.   Nature Protocols

2-Methyltetrahydrofuran and cyclopentyl methyl ether for green solid-phase peptide synthesis

(2015) Yahya E. Jad et al.   AMINO ACIDS

Antimicrobial Peptides with Potential for Biofilm Eradication: Synthesis and Structure Activity Relationship Studies of Battacin Peptides

(2015) Gayan Heruka De Zoysa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Butelase 1: A Versatile Ligase for Peptide and Protein Macrocyclization

(2015) Giang K. T. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Methods, setup and safe handling for anhydrous hydrogen fluoride cleavage in Boc solid-phase peptide synthesis

(2015) Markus Muttenthaler et al.   Nature Protocols

Peptide synthesis beyond DMF: THF and ACN as excellent and friendlier alternatives

(2015) Yahya E. Jad et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Amide and Peptide Bond Formation in Water at Room Temperature

(2015) Christopher M. Gabriel et al.   ORGANIC LETTERS

An efficient mechanochemical synthesis of amides and dipeptides using 2,4,6-trichloro-1,3,5-triazine and PPh3

(2015) Chuthamat Duangkamol et al.   RSC Advances

Aqueous microwave-assisted solid-phase peptide synthesis using Fmoc strategy. III: Racemization studies and water-based synthesis of histidine-containing peptides

(2014) Keiko Hojo et al.   AMINO ACIDS

Butelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesis

(2014) Giang K T Nguyen et al.   Nature Chemical Biology

High-Efficiency Solid Phase Peptide Synthesis (HE-SPPS)

(2014) Jonathan M. Collins et al.   ORGANIC LETTERS

Antimicrobial peptides againstPseudomonas syringaepv.actinidiaeandErwinia amylovora: Chemical synthesis, secondary structure, efficacy, and mechanistic investigations

(2013) Alan Cameron et al.   BIOPOLYMERS

American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Diagnosis and Treatment of Acromegaly-2011 Update

(2013) Laurence Katznelson et al.   Endocrine Practice

K-Oxyma: a Strong Acylation-Promoting, 2-CTC Resin-Friendly Coupling Additive

(2013) Prabhakar Cherkupally et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Antimicrobial peptides: new drugs for bad bugs?

(2013) Jonathan D Steckbeck et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Environmentally benign peptide synthesis using liquid-assisted ball-milling: application to the synthesis of Leu-enkephalin

(2013) Julien Bonnamour et al.   GREEN CHEMISTRY

COMU: scope and limitations of the latest innovation in peptide acyl transfer reagents

(2013) Ramon Subirós-Funosas et al.   JOURNAL OF PEPTIDE SCIENCE

Aqueous Microwave-Assisted Solid-Phase Peptide Synthesis Using Fmoc Strategy. II. Racemization Studies and Water Based Synthesis of Cysteine- Containing Peptides

(2013) Keiko Hojo et al.   PROTEIN AND PEPTIDE LETTERS

Efficient activity of magnesium–aluminium hydrotalcite in the synthesis of amides

(2013) José Antonio Morales-Serna et al.   RSC Advances

Solventless Synthesis of N-Protected Amino Acids in a Ball Mill

(2013) Laure Konnert et al.   ACS Sustainable Chemistry & Engineering

Controlled Solid Phase Peptide Bond Formation Using N-Carboxyanhydrides and PEG Resins in Water.

(2013) Rossella De Marco et al.   ACS Sustainable Chemistry & Engineering

Evaluation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N,N-dimethylformamide

(2012) Donna S. MacMillan et al.   GREEN CHEMISTRY

Evaluation of COMU as a coupling reagent for in situ neutralization Boc solid phase peptide synthesis

(2012) Claudia U. Hjørringgaard et al.   JOURNAL OF PEPTIDE SCIENCE

Aqueous Microwave-Assisted Solid-Phase Peptide Synthesis Using Fmoc Strategy: In-Water Synthesis of "Difficult Sequences"

(2012) Keiko Hojo et al.   PROTEIN AND PEPTIDE LETTERS

Sortase A-catalyzed peptide cyclization for the synthesis of macrocyclic peptides and glycopeptides

(2011) Zhimeng Wu et al.   CHEMICAL COMMUNICATIONS

Peptide Coupling Reagents, More than a Letter Soup

(2011) Ayman El-Faham et al.   CHEMICAL REVIEWS

Development of a method for environmentally friendly chemical peptide synthesis in water using water-dispersible amino acid nanoparticles

(2011) Keiko Hojo et al.   Chemistry Central Journal

TPGS-750-M: A Second-Generation Amphiphile for Metal-Catalyzed Cross-Couplings in Water at Room Temperature

(2011) Bruce H. Lipshutz et al.   JOURNAL OF ORGANIC CHEMISTRY

Peptide synthesis ‘in water’ by a solution-phase method using water-dispersible nanoparticle Boc-amino acid

(2011) Keiko Hojo et al.   JOURNAL OF PEPTIDE SCIENCE

Efficient solid-phase synthesis of cyclic RGD peptides under controlled microwave heating

(2011) Keiichi Yamada et al.   TETRAHEDRON LETTERS

Chemoenzymatic synthesis of glycosylphosphatidylinositol-anchored glycopeptides

(2010) Zhimeng Wu et al.   CHEMICAL COMMUNICATIONS

Dimethylformamide metabolism following self-harm using a veterinary euthanasia product

(2010) Philippe Hantson et al.   CLINICAL TOXICOLOGY

Green Synthesis of α,β- and β,β-Dipeptides under Solvent-Free Conditions

(2010) José G. Hernández et al.   JOURNAL OF ORGANIC CHEMISTRY

ChemMatrix® for complex peptides and combinatorial chemistry

(2010) Yésica García-Ramos et al.   JOURNAL OF PEPTIDE SCIENCE

Sortase A-Catalyzed Transpeptidation of Glycosylphosphatidylinositol Derivatives for Chemoenzymatic Synthesis of GPI-Anchored Proteins

(2010) Zhimeng Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tissue Dissociation Enzyme Neutral Protease Assessment

(2010) A.G. Breite et al.   TRANSPLANTATION PROCEEDINGS

Solvent-Free Synthesis of Peptides

(2009) Valérie Declerck et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

COMU: A Safer and More Effective Replacement for Benzotriazole-Based Uronium Coupling Reagents

(2009) Ayman El-Faham et al.   CHEMISTRY-A EUROPEAN JOURNAL

Oxyma: An Efficient Additive for Peptide Synthesis to Replace the Benzotriazole-Based HOBt and HOAt with a Lower Risk of Explosion[1]

(2009) Ramon Subirós-Funosas et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Straight Path to Circular Proteins

(2009) John M. Antos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins

(2009) Gerardo A. Acosta et al.   JOURNAL OF PEPTIDE SCIENCE

COMU: A third generation of uronium-type coupling reagents

(2009) Ayman El-Faham et al.   JOURNAL OF PEPTIDE SCIENCE

Peptide Synthesis in Aqueous Environments: The Role of Extreme Conditions on Peptide Bond Formation and Peptide Hydrolysis

(2009) Eduard Schreiner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sortase-Catalyzed Peptide−Glycosylphosphatidylinositol Analogue Ligation

(2009) Xueqing Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Solid-Phase Peptide Synthesis in Water Using Microwave-Assisted Heating

(2009) Athanassios S. Galanis et al.   ORGANIC LETTERS

Microwave irradiation and COMU: a potent combination for solid-phase peptide synthesis

(2009) Ramon Subiros-Funosas et al.   TETRAHEDRON LETTERS

Enzymatic synthesis of peptides on a solid support

(2008) Rose Haddoub et al.   ORGANIC & BIOMOLECULAR CHEMISTRY