Mechanistic Insights of Astrocyte-Mediated Hyperactive Autophagy and Loss of Motor Neuron Function in SOD1L39R Linked Amyotrophic Lateral Sclerosis
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mechanistic Insights of Astrocyte-Mediated Hyperactive Autophagy and Loss of Motor Neuron Function in SOD1L39R Linked Amyotrophic Lateral Sclerosis
Authors
Keywords
-
Journal
MOLECULAR NEUROBIOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-07-16
DOI
10.1007/s12035-020-02006-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1
- (2019) Judith M. Silverman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease
- (2019) Angelique di Domenico et al. Stem Cell Reports
- Tracking a Fast-Moving Disease: Longitudinal Markers, Monitoring, and Clinical Trial Endpoints in ALS
- (2019) Rangariroyashe Hannah Chipika et al. Frontiers in Neurology
- Modeling vanishing white matter disease with patient‐derived induced pluripotent stem cells reveals astrocytic dysfunction
- (2019) Ling Zhou et al. CNS Neuroscience & Therapeutics
- Context and Complexity: How Ionic Conductances Interact to Control Neuronal Firing
- (2019) Bruce Bean BIOPHYSICAL JOURNAL
- Mitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation
- (2019) Brittany L. Baechler et al. Autophagy
- Generation and characterization of a human induced pluripotent stem cell (iPSC) line (HEBHMUi001-A) from a sporadic Parkinson's disease patient
- (2019) Jun Ma et al. Stem Cell Research
- Structural Properties and Interaction Partners of Familial ALS-Associated SOD1 Mutants
- (2019) Jisen Huai et al. Frontiers in Neurology
- Dysregulated autophagy as a new aspect of the molecular pathogenesis of Krabbe disease
- (2019) Ambra Del Grosso et al. NEUROBIOLOGY OF DISEASE
- C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis
- (2019) Qiang Shao et al. Autophagy
- Autophagy Induction as a Therapeutic Strategy for Neurodegenerative Diseases
- (2019) Alvin Djajadikerta et al. JOURNAL OF MOLECULAR BIOLOGY
- Mechanisms of protein toxicity in neurodegenerative diseases
- (2018) Chang Geon Chung et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- SOD1 in Amyotrophic Lateral Sclerosis: “Ambivalent” Behavior Connected to the Disease
- (2018) Orietta Pansarasa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cerebrospinal Fluid from Patients with Sporadic Amyotrophic Lateral Sclerosis Induces Degeneration of Motor Neurons Derived from Human Embryonic Stem Cells
- (2018) Rajendrarao Sumitha et al. MOLECULAR NEUROBIOLOGY
- Inflammation, Immunity and ALS: Etiology and Pathology
- (2018) Miles Lyon et al. MUSCLE & NERVE
- Generation of defined neural populations from pluripotent stem cells
- (2018) Sarah F. McComish et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy
- (2018) Giacomo Frati et al. Cell Death & Disease
- The roles and mechanisms of G3BP1 in tumour promotion
- (2018) Cong-Hui Zhang et al. JOURNAL OF DRUG TARGETING
- Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs
- (2018) Manoj Kumar Jaiswal MEDICINAL RESEARCH REVIEWS
- EzColocalization: An ImageJ plugin for visualizing and measuring colocalization in cells and organisms
- (2018) Weston Stauffer et al. Scientific Reports
- Risk factors in Swedish young men for amyotrophic lateral sclerosis in adulthood
- (2017) Maria Åberg et al. JOURNAL OF NEUROLOGY
- Electrophysiological and Pathological Characterization of the Period of Heightened Vulnerability to Repetitive Injury in an in Vitro Stretch Model
- (2017) Gwen B. Effgen et al. JOURNAL OF NEUROTRAUMA
- Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms
- (2017) Martin Madill et al. Molecular Brain
- ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics
- (2016) Jozsef Gal et al. ACTA NEUROPATHOLOGICA
- NewIn VitroModels to Study Amyotrophic Lateral Sclerosis
- (2016) Monika Myszczynska et al. BRAIN PATHOLOGY
- Stress granules at the intersection of autophagy and ALS
- (2016) Zachary Monahan et al. BRAIN RESEARCH
- A central role for calcineurin in protein misfolding neurodegenerative diseases
- (2016) Syed Zahid Ali Shah et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Potential Links between Cytoskeletal Disturbances and Electroneurophysiological Dysfunctions Induced in the Central Nervous System by Inorganic Nanoparticles
- (2016) Yiyuan Kang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Impaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron Degeneration
- (2016) Brittany M. Edens et al. Frontiers in Cellular Neuroscience
- Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS
- (2016) Junghee Lee et al. Experimental Neurobiology
- Sequential activation of microglia and astrocyte cytokine expression precedes increased iba-1 or GFAP immunoreactivity following systemic immune challenge
- (2015) Diana M. Norden et al. GLIA
- Derivation of Adult Human Fibroblasts and their Direct Conversion into Expandable Neural Progenitor Cells
- (2015) Sandra Meyer et al. Jove-Journal of Visualized Experiments
- Human Astrocytes: Secretome Profiles of Cytokines and Chemokines
- (2014) Sung S. Choi et al. PLoS One
- The Biogenesis of Lysosomes and Lysosome-Related Organelles
- (2014) J. P. Luzio et al. Cold Spring Harbor Perspectives in Biology
- Mutant Copper-Zinc Superoxide Dismutase (SOD1) Induces Protein Secretion Pathway Alterations and Exosome Release in Astrocytes
- (2013) Manuela Basso et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions
- (2012) Jeanette Beers et al. Nature Protocols
- Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks
- (2012) Yichen Shi et al. Nature Protocols
- Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells
- (2012) N. Egawa et al. Science Translational Medicine
- An Efficient Nonviral Method to Generate Integration-Free Human-Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells
- (2012) Keisuke Okita et al. STEM CELLS
- Directed differentiation of functional astroglial subtypes from human pluripotent stem cells
- (2011) Robert Krencik et al. Nature Protocols
- Physical fitness, but not muscle strength, is a risk factor for death in amyotrophic lateral sclerosis at an early age
- (2010) Peter Mattsson et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Evidence of endoplasmic reticular stress in the spinal motor neurons exposed to CSF from sporadic amyotrophic lateral sclerosis patients
- (2010) K. Vijayalakshmi et al. NEUROBIOLOGY OF DISEASE
- Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
- (2010) B.-Y. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cerebrospinal Fluid from sporadic Amyotrophic Lateral Sclerosis patients induces degeneration of a cultured motor neuron cell line
- (2009) K. Vijayalakshmi et al. BRAIN RESEARCH
- Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells
- (2008) Maria C.N. Marchetto et al. Cell Stem Cell
- Human Embryonic Stem Cell-Derived Motor Neurons Are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation
- (2008) Francesco Paolo Di Giorgio et al. Cell Stem Cell
- ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
- (2008) H. Nishitoh et al. GENES & DEVELOPMENT
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now