Journal
STEM CELL RESEARCH
Volume 36, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.scr.2019.101417
Keywords
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Funding
- Hebei Medical University
- Natural Science Foundation of China [81801278]
- China Scholarship Council [201608130015]
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We generated a human induced pluripotent stem cell (iPSC) line from the skin fibroblasts of a 62-year-old female patient clinically diagnosed with sporadic Parkinson's disease (PD). The generated iPSCs maintained their normal karyotype, expressed pluripotency stem cell markers, and were demonstrated to be capable of differentiating into cells representative of the three embryonic germ layers. The generated line could be used for PD modeling in order to understand the mechanisms that influence the disorder.
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