Omega-3 Fatty Acid-Enriched Fish Oil and Selenium Combination Modulates Endoplasmic Reticulum Stress Response Elements and Reverses Acquired Gefitinib Resistance in HCC827 Lung Adenocarcinoma Cells

Protective Effect of Low Molecular Weight Seleno-Aminopolysaccharide on the Intestinal Mucosal Oxidative Damage

(2019) Zheng-Shun Wen et al.   Marine Drugs

Glucose-Regulated Protein 78 Signaling Regulates Hypoxia-Induced Epithelial–Mesenchymal Transition in A549 Cells

(2019) Ling-Ling Sun et al.   Frontiers in Oncology

ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining “stemness”

(2019) Patricia Dauer et al.   Cell Death & Disease

Overcoming acquired resistance of gefitinib in lung cancer cells without T790M by AZD9291 or Twist1 knockdown in vitro and in vivo

(2019) Zhongwei Liu et al.   ARCHIVES OF TOXICOLOGY

AXL degradation in combination with EGFR-TKI can delay and overcome acquired resistance in human non-small cell lung cancer cells

(2019) Donghwa Kim et al.   Cell Death & Disease

The EGFR Exon 19 Mutant L747-A750>P Exhibits Distinct Sensitivity to Tyrosine Kinase Inhibitors in Lung Adenocarcinoma

(2019) Anna Truini et al.   CLINICAL CANCER RESEARCH

Targeting the COX2/MET/TOPK signaling axis induces apoptosis in gefitinib-resistant NSCLC cells

(2019) Juanjuan Xiao et al.   Cell Death & Disease

EIF3D promotes sunitinib resistance of renal cell carcinoma by interacting with GRP78 and inhibiting its degradation

(2019) Hai Huang et al.   EBioMedicine

Overexpression of endoplasmic reticulum stress-related proteins, XBP1s and GRP78, predicts poor prognosis in pulmonary adenocarcinoma

(2018) Dohee Kwon et al.   LUNG CANCER

Heterozygosity of chaperone Grp78 reduces intestinal stem cell regeneration potential and protects against adenoma formation.

(2018) Jooske F van Lidth de Jeude et al.   CANCER RESEARCH

Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI

(2018) Chien-Hui Weng et al.   ONCOGENE

Effects of selenium on antioxidant enzymes and photosynthesis in the edible seaweed Gracilaria lemaneiformis

(2018) Qing Wang et al.   JOURNAL OF APPLIED PHYCOLOGY

Opposite Regulation of CHOP and GRP78 and Synergistic Apoptosis Induction by Selenium Yeast and Fish Oil via AMPK Activation in Lung Adenocarcinoma Cells

(2018) Ruey-Ho Kao et al.   Nutrients

The omega-3 polyunsaturated fatty acid docosahexaenoic acid inhibits proliferation and progression of non-small cell lung cancer cells through the reactive oxygen species-mediated inactivation of the PI3K /Akt pathway

(2017) Yuanqin Yin et al.   Lipids in Health and Disease

Selenium-Containing Polysaccharide-Protein Complex in Se-Enriched Ulva fasciata Induces Mitochondria-Mediated Apoptosis in A549 Human Lung Cancer Cells

(2017) Xian Sun et al.   Marine Drugs

GRP78 at the Centre of the Stage in Cancer and Neuroprotection

(2017) Caty Casas   Frontiers in Neuroscience

Endoplasmic reticulum stress signaling and chemotherapy resistance in solid cancers

(2017) T Avril et al.   Oncogenesis

Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice

(2017) Amy S. Lee et al.   Scientific Reports

Antibody Targeting GRP78 Enhances the Efficacy of Radiation Therapy in Human Glioblastoma and Non–Small Cell Lung Cancer Cell Lines and Tumor Models

(2016) David Y.A. Dadey et al.   CLINICAL CANCER RESEARCH

Autophagy inhibition facilitates erlotinib cytotoxicity in lung cancer cells through modulation of endoplasmic reticulum stress

(2016) ZHONGLIANG WANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

A Comparison of Fish Oil Sources for Parenteral Lipid Emulsions in a Murine Model

(2016) Gillian L. Fell et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Expression of GRP78, Master Regulator of the Unfolded Protein Response, Increases Chemoresistance in Pancreatic Ductal Adenocarcinoma

(2016) J. B. Gifford et al.   MOLECULAR CANCER THERAPEUTICS

Omega-3 Fatty Acids and Cancer Cell Cytotoxicity: Implications for Multi-Targeted Cancer Therapy

(2016) Donatella D’Eliseo et al.   Journal of Clinical Medicine

EGFR-independent autophagy induction with gefitinib and enhancement of its cytotoxic effect by targeting autophagy with clarithromycin in non-small cell lung cancer cells

(2015) Shohei Sugita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DUSP1 Expression Induced by HDAC1 Inhibition Mediates Gefitinib Sensitivity in Non-Small Cell Lung Cancers

(2015) Y.-C. Lin et al.   CLINICAL CANCER RESEARCH

Role of GRP78 in promoting therapeutic-resistant breast cancer

(2015) Katherine L Cook et al.   Future Medicinal Chemistry

Overexpressed GRP78 affects EMT and cell-matrix adhesion via autocrine TGF-β/Smad2/3 signaling

(2015) Lichao Zhang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The 2015 World Health Organization Classification of Lung Tumors

(2015) William D. Travis et al.   Journal of Thoracic Oncology

Hsp27 Inhibition with OGX-427 Sensitizes Non-Small Cell Lung Cancer Cells to Erlotinib and Chemotherapy

(2015) B. Lelj-Garolla et al.   MOLECULAR CANCER THERAPEUTICS

Cancer chemoprevention research with selenium in the post-SELECT era: Promises and challenges

(2015) Junxuan Lü et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

GRP78 confers the resistance to 5-FU by activating the c-Src/LSF/TS Axis in hepatocellular carcinoma

(2015) Yan-jiao Gu et al.   Oncotarget

Docosahexaenoic Acid Induces Cell Death in Human Non-Small Cell Lung Cancer Cells by Repressing mTOR via AMPK Activation and PI3K/Akt Inhibition

(2015) Nayeong Kim et al.   Biomed Research International

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Selenium enhances antioxidant activity and photosynthesis in Ulva fasciata

(2014) Yu Zhong et al.   JOURNAL OF APPLIED PHYCOLOGY

Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell-like Properties in Cancer Cells

(2013) K. Shien et al.   CANCER RESEARCH

Fish oil omega-3 fatty acids and cardio-metabolic health, alone or with statins

(2013) Anne Marie Minihane   EUROPEAN JOURNAL OF CLINICAL NUTRITION

β-Catenin overexpression is associated with gefitinib resistance in non-small cell lung cancer cells

(2013) Xia Fang et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop

(2013) K E Ware et al.   Oncogenesis

DHA induces apoptosis by altering the expression and cellular location of GRP78 in colon cancer cell lines

(2012) Elena Fasano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

(2012) Zhenfeng Zhang et al.   NATURE GENETICS

Supplementation with fish oil increases first-line chemotherapy efficacy in patients with advanced nonsmall cell lung cancer

(2011) Rachel A. Murphy et al.   CANCER

Current knowledge in species-related bioavailability of selenium in food

(2011) Celine Thiry et al.   FOOD CHEMISTRY

Targeting Endoplasmic Reticulum Stress and Akt with OSU-03012 and Gefitinib or Erlotinib to Overcome Resistance to Epidermal Growth Factor Receptor Inhibitors

(2008) Y.-C. Wang et al.   CANCER RESEARCH

DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis

(2008) Caroline Hild Jakobsen et al.   JOURNAL OF LIPID RESEARCH