Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice
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Title
Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice
Authors
Keywords
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Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-02-01
DOI
10.1038/srep40919
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Note: Only part of the references are listed.- Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells
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- (2016) J. B. Gifford et al. MOLECULAR CANCER THERAPEUTICS
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- (2016) Mayurbhai R. Patel et al. NANO LETTERS
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- (2015) Laurence Booth et al. JOURNAL OF CELLULAR PHYSIOLOGY
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- (2013) Katherine L Cook et al. Future Medicinal Chemistry
- Cancer Cells Resistant to Therapy Promote Cell Surface Relocalization of GRP78 Which Complexes with PI3K and Enhances PI(3,4,5)P3 Production
- (2013) Yi Zhang et al. PLoS One
- The Molecular Chaperone GRP78/BiP in the Development of Chemoresistance: Mechanism and Possible Treatment
- (2013) Corinna Roller et al. Frontiers in Pharmacology
- The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies
- (2012) B Luo et al. ONCOGENE
- Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting
- (2011) Min Ni et al. BIOCHEMICAL JOURNAL
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- Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78
- (2010) M. S. Gorbatyuk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders
- (2009) Miao Wang et al. ANTIOXIDANTS & REDOX SIGNALING
- GRP78: A Multifunctional Receptor on the Cell Surface
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- Critical Role of the Stress Chaperone GRP78/BiP in Tumor Proliferation, Survival, and Tumor Angiogenesis in Transgene-Induced Mammary Tumor Development
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- The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
- (2008) J Li et al. CELL DEATH AND DIFFERENTIATION
- Aging Impairs the Unfolded Protein Response to Sleep Deprivation and Leads to Proapoptotic Signaling
- (2008) N. Naidoo et al. JOURNAL OF NEUROSCIENCE
- Stress Chaperone GRP78/BiP Confers Chemoresistance to Tumor-Associated Endothelial Cells
- (2008) J. J. Virrey et al. MOLECULAR CANCER RESEARCH
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- (2008) Y. Fu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2007) Jonathan E. Nuss et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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