In-silico analysis to identify the role of MEN1 missense mutations in breast cancer

Evaluation of performance of leading algorithms for variant pathogenicity predictions and designing a combinatory predictor method: application to Rett syndrome variants

(2019) Satishkumar Ranganathan Ganakammal et al.   PeerJ

CADD: predicting the deleteriousness of variants throughout the human genome

(2018) Philipp Rentzsch et al.   NUCLEIC ACIDS RESEARCH

COSMIC: the Catalogue Of Somatic Mutations In Cancer

(2018) John G Tate et al.   NUCLEIC ACIDS RESEARCH

SDM: a server for predicting effects of mutations on protein stability

(2017) Arun Prasad Pandurangan et al.   NUCLEIC ACIDS RESEARCH

Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer

(2017) Koen M.A. Dreijerink et al.   Cell Reports

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

(2016) Nilah M. Ioannidis et al.   AMERICAN JOURNAL OF HUMAN GENETICS

SAAMBE: Webserver to Predict the Charge of Binding Free Energy Caused by Amino Acids Mutations

(2016) Marharyta Petukh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SAAFEC: Predicting the Effect of Single Point Mutations on Protein Folding Free Energy Using a Knowledge-Modified MM/PBSA Approach

(2016) Ivan Getov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A spectral approach integrating functional genomic annotations for coding and noncoding variants

(2016) Iuliana Ionita-Laza et al.   NATURE GENETICS

MutaBind estimates and interprets the effects of sequence variants on protein–protein interactions

(2016) Minghui Li et al.   NUCLEIC ACIDS RESEARCH

VariSNP, A Benchmark Database for Variations From dbSNP

(2015) Gerard C.P. Schaafsma et al.   HUMAN MUTATION

Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies

(2015) C. Dong et al.   HUMAN MOLECULAR GENETICS

ZDOCK server: interactive docking prediction of protein-protein complexes and symmetric multimers

(2014) B. G. Pierce et al.   BIOINFORMATICS

Raloxifene inhibits menin-dependent estrogen receptor activation in breast cancer cells

(2014) H. Imachi et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Breast-Cancer Predisposition in Multiple Endocrine Neoplasia Type 1

(2014) Koen M.A. Dreijerink et al.   NEW ENGLAND JOURNAL OF MEDICINE

DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach

(2014) D. E. V. Pires et al.   NUCLEIC ACIDS RESEARCH

UniProt: a hub for protein information

(2014)   NUCLEIC ACIDS RESEARCH

mCSM: predicting the effects of mutations in proteins using graph-based signatures

(2013) Douglas E. V. Pires et al.   BIOINFORMATICS

Identifying Mendelian disease genes with the Variant Effect Scoring Tool

(2013) Hannah Carter et al.   BMC GENOMICS

BeAtMuSiC: prediction of changes in protein–protein binding affinity on mutations

(2013) Yves Dehouck et al.   NUCLEIC ACIDS RESEARCH

Menin: a scaffold protein that controls gene expression and cell signaling

(2013) Smita Matkar et al.   TRENDS IN BIOCHEMICAL SCIENCES

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

Menin, a product of the MENI gene, binds to estrogen receptor to enhance its activity in breast cancer cells: possibility of a novel predictive factor for tamoxifen resistance

(2009) Hitomi Imachi et al.   BREAST CANCER RESEARCH AND TREATMENT

Identification of deleterious mutations within three human genomes

(2009) S. Chun et al.   GENOME RESEARCH

Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the gene

(2007) Manuel C. Lemos et al.   HUMAN MUTATION