SAAFEC: Predicting the Effect of Single Point Mutations on Protein Folding Free Energy Using a Knowledge-Modified MM/PBSA Approach

Using DelPhi Capabilities to Mimic Protein’s Conformational Reorganization with Amino Acid Specific Dielectric Constants

(2016) Lin Wang et al.   Communications in Computational Physics

Impact of Rett Syndrome Mutations on MeCP2 MBD Stability

(2015) Tugba G. Kucukkal et al.   BIOCHEMISTRY

Structural and physico-chemical effects of disease and non-disease nsSNPs on proteins

(2015) Tugba G Kucukkal et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons

(2015) Melanie May et al.   HUMAN MOLECULAR GENETICS

On Human Disease-Causing Amino Acid Variants: Statistical Study of Sequence and Structural Patterns

(2015) Marharyta Petukh et al.   HUMAN MUTATION

Mutations in the KDM5C ARID Domain and Their Plausible Association with Syndromic Claes-Jensen-Type Disease

(2015) Yunhui Peng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Predicting Binding Free Energy Change Caused by Point Mutations with Knowledge-Modified MM/PBSA Method

(2015) Marharyta Petukh et al.   PLoS Computational Biology

Computational and Experimental Approaches to Reveal the Effects of Single Nucleotide Polymorphisms with Respect to Disease Diagnostics

(2014) Tugba Kucukkal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Y328C missense mutation in spermine synthase causes a mild form of Snyder–Robinson syndrome

(2013) Zhe Zhang et al.   HUMAN MOLECULAR GENETICS

A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation

(2013) Luigi Boccuto et al.   HUMAN MOLECULAR GENETICS

Understanding Molecular Effects of Naturally Occurring Genetic Differences

(2013) Emil Alexov et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular Mechanisms of Disease-Causing Missense Mutations

(2013) Shannon Stefl et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure-based prediction of the effects of a missense variant on protein stability

(2012) Yang Yang et al.   AMINO ACIDS

Predicting folding free energy changes upon single point mutations

(2012) Zhe Zhang et al.   BIOINFORMATICS

Analyzing Effects of Naturally Occurring Missense Mutations

(2012) Zhe Zhang et al.   Computational and Mathematical Methods in Medicine

An X-linked channelopathy with cardiomegaly due to a CLIC2 mutation enhancing ryanodine receptor channel activity

(2012) Kyoko Takano et al.   HUMAN MOLECULAR GENETICS

A graphical interface for the FoldX forcefield

(2011) J. Van Durme et al.   BIOINFORMATICS

PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality

(2011) Yves Dehouck et al.   BMC BIOINFORMATICS

Performance of mutation pathogenicity prediction methods on missense variants

(2011) Janita Thusberg et al.   HUMAN MUTATION

A Smoothed Backbone-Dependent Rotamer Library for Proteins Derived from Adaptive Kernel Density Estimates and Regressions

(2011) Maxim V. Shapovalov et al.   STRUCTURE

Computational analysis of missense mutations causing Snyder-Robinson syndrome

(2010) Zhe Zhang et al.   HUMAN MUTATION

Performance of protein stability predictors

(2010) Sofia Khan et al.   HUMAN MUTATION

High-Performance Scalable Molecular Dynamics Simulations of a Polarizable Force Field Based on Classical Drude Oscillators in NAMD

(2010) Wei Jiang et al.   Journal of Physical Chemistry Letters

Stability effects of mutations and protein evolvability

(2009) Nobuhiko Tokuriki et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Predicting free energy changes using structural ensembles

(2008) Alexander Benedix et al.   NATURE METHODS