SDM: a server for predicting effects of mutations on protein stability

mCSM–NA: predicting the effects of mutations on protein–nucleic acids interactions

(2017) Douglas E.V. Pires et al.   NUCLEIC ACIDS RESEARCH

Familial STAG2 germline mutation defines a new human cohesinopathy

(2017) Fernanda C. Soardi et al.   npj Genomic Medicine

SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity

(2017) Ruth T. Casey et al.   Molecular Genetics & Genomic Medicine

Computational approaches for predicting mutant protein stability

(2016) Shweta Kulshreshtha et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Next generation sequencing: implications in personalized medicine and pharmacogenomics

(2016) Bahareh Rabbani et al.   Molecular BioSystems

mCSM-AB: a web server for predicting antibody–antigen affinity changes upon mutation with graph-based signatures

(2016) Douglas E.V. Pires et al.   NUCLEIC ACIDS RESEARCH

Variation in Human Cytochrome P-450 Drug-Metabolism Genes: A Gateway to the Understanding of Plasmodium vivax Relapses

(2016) Ana Carolina Rios Silvino et al.   PLoS One

mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance

(2016) Douglas E. V. Pires et al.   Scientific Reports

Ubiquitin-Dependent Modification of Skeletal Muscle by the Parasitic Nematode, Trichinella spiralis

(2016) Rhiannon R. White et al.   PLoS Pathogens

In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity

(2016) Douglas E. V. Pires et al.   Scientific Reports

INPS: predicting the impact of non-synonymous variations on protein stability from sequence

(2015) Piero Fariselli et al.   BIOINFORMATICS

MAESTRO - multi agent stability prediction upon point mutations

(2015) Josef Laimer et al.   BMC BIOINFORMATICS

Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’ in Italy

(2015) Martina Nemethova et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Network effects of disease mutations

(2015) Darren J. Burgess   NATURE REVIEWS GENETICS

Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma

(2015) M. Jafri et al.   Cancer Discovery

CHOPIN: a web resource for the structural and functional proteome of Mycobacterium tuberculosis

(2015) Bernardo Ochoa-Montaño et al.   Database-The Journal of Biological Databases and Curation

Platinum: a database of experimentally measured effects of mutations on structurally defined protein–ligand complexes

(2014) Douglas E.V. Pires et al.   NUCLEIC ACIDS RESEARCH

DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach

(2014) D. E. V. Pires et al.   NUCLEIC ACIDS RESEARCH

mCSM: predicting the effects of mutations in proteins using graph-based signatures

(2013) Douglas E. V. Pires et al.   BIOINFORMATICS

Depth: a web server to compute depth, cavity sizes, detect potential small-molecule ligand-binding cavities and predict the pKa of ionizable residues in proteins

(2013) Kuan Pern Tan et al.   NUCLEIC ACIDS RESEARCH

Protein stability by number: high-throughput and statistical approaches to one of protein science's most difficult problems

(2011) Thomas J Magliery et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

SDM--a server for predicting effects of mutations on protein stability and malfunction

(2011) C. L. Worth et al.   NUCLEIC ACIDS RESEARCH

Prots: A fragment based protein thermo-stability potential

(2011) Yunqi Li et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Sequence feature-based prediction of protein stability changes upon amino acid substitutions

(2010) Shaolei Teng et al.   BMC GENOMICS

Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins

(2010) Sungsam Gong et al.   PLoS One

Environment-specific amino acid substitution tables: Tertiary templates and prediction of protein folds

(2010) John Overington et al.   PROTEIN SCIENCE

Role of conformational sampling in computing mutation-induced changes in protein structure and stability

(2010) Elizabeth H. Kellogg et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Ulla: a program for calculating environment-specific amino acid substitution tables

(2009) Semin Lee et al.   BIOINFORMATICS

Fast and accurate predictions of protein stability changes upon mutations using statistical potentials and neural networks: PoPMuSiC-2.0

(2009) Yves Dehouck et al.   BIOINFORMATICS

CREDO: A Protein-Ligand Interaction Database for Drug Discovery

(2009) Adrian Schreyer et al.   Chemical Biology & Drug Design

Accurate prediction of stability changes in protein mutants by combining machine learning with structure based computational mutagenesis

(2008) M. Masso et al.   BIOINFORMATICS

Satisfaction of hydrogen-bonding potential influences the conservation of polar sidechains

(2008) Catherine L. Worth et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS