Gentamicin-Induced Acute Kidney Injury in an Animal Model Involves Programmed Necrosis of the Collecting Duct

Integrin-Linked Kinase Deficiency in Collecting Duct Principal Cell Promotes Necroptosis of Principal Cell and Contributes to Kidney Inflammation and Fibrosis

(2019) Ming Huang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lethal (3) malignant brain tumor-like 2 (L3MBTL2) protein protects against kidney injury by inhibiting the DNA damage–p53–apoptosis pathway in renal tubular cells

(2018) Huihui Huang et al.   KIDNEY INTERNATIONAL

RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism

(2018) Wenjing Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reducing Inflammatory Cytokine Production from Renal Collecting Duct Cells by Inhibiting GATA2 Ameliorates Acute Kidney Injury

(2017) Lei Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

Re-characterization of the Glomerulopathy in CD2AP Deficient Mice by High-Resolution Helium Ion Scanning Microscopy

(2017) Kenji Tsuji et al.   Scientific Reports

Regulated necrosis: disease relevance and therapeutic opportunities

(2016) Marcus Conrad et al.   NATURE REVIEWS DRUG DISCOVERY

Acute kidney injury and chronic kidney disease: From the laboratory to the clinic

(2016) David A. Ferenbach et al.   Nephrologie & Therapeutique

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

(2016) Yasushi Ito et al.   SCIENCE

Necroptosis in acute kidney injury: a shedding light

(2016) S Wang et al.   Cell Death & Disease

A Role for Tubular Necroptosis in Cisplatin-Induced AKI

(2015) Y. Xu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice

(2015) José Belizário et al.   MEDIATORS OF INFLAMMATION

ASC in Renal Collecting Duct Epithelial Cells Contributes to Inflammation and Injury after Unilateral Ureteral Obstruction

(2014) Takanori Komada et al.   AMERICAN JOURNAL OF PATHOLOGY

RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction

(2014) Mark Luedde et al.   CARDIOVASCULAR RESEARCH

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Regulated Cell Death in AKI

(2014) A. Linkermann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Necroptosis

(2014) Andreas Linkermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synchronized renal tubular cell death involves ferroptosis

(2014) Andreas Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Necroptosis in health and diseases

(2014) Wen Zhou et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

RIP3: a molecular switch for necrosis and inflammation

(2013) K. Moriwaki et al.   GENES & DEVELOPMENT

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death

(2013) Dimitry Ofengeim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase

(2012) A Degterev et al.   CELL DEATH AND DIFFERENTIATION

Rip1 (Receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

(2012) Andreas Linkermann et al.   KIDNEY INTERNATIONAL

Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice

(2011) Katsuhito Fujiu et al.   JOURNAL OF CLINICAL INVESTIGATION

Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway

(2010) Ana I. Morales et al.   KIDNEY INTERNATIONAL

New insights into the mechanism of aminoglycoside nephrotoxicity: an integrative point of view

(2010) Jose M. Lopez-Novoa et al.   KIDNEY INTERNATIONAL

Gentamicin-induced nephrotoxicity: Do we have a promising therapeutic approach to blunt it?

(2010) Pitchai Balakumar et al.   PHARMACOLOGICAL RESEARCH

An Integrative Overview on the Mechanisms Underlying the Renal Tubular Cytotoxicity of Gentamicin

(2010) Y. Quiros et al.   TOXICOLOGICAL SCIENCES

Light-Microscopic Immunocytochemistry for Gentamicin and Its Use for Studying Uptake of the Drug in Kidney

(2009) K. Fujiwara et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats

(2009) Srinivasan Kalayarasan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Deletion of the Met receptor in the collecting duct decreases renal repair following ureteral obstruction

(2009) Hong Ma et al.   KIDNEY INTERNATIONAL

Gentamicin-associated acute kidney injury

(2009) N. M. Selby et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Mechanisms of Renal Apoptosis in Health and Disease

(2008) A. B. Sanz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology