Cytoskeletal regulation of synaptogenesis in a model of human fetal brain development

Neuronal migration in the CNS during development and disease: insights from in vivo and in vitro models

(2019) Isabel Yasmin Buchsbaum et al.   DEVELOPMENT

Nestin in immature embryonic neurons affects axon growth cone morphology and Semaphorin3a sensitivity

(2019) C. J. Bott et al.   MOLECULAR BIOLOGY OF THE CELL

Human-Derived Brain Models: Windows Into Neuropsychiatric Disorders and Drug Therapies

(2019) Alexis Papariello et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

DiI‐mediated analysis of presynaptic and postsynaptic structures in human postmortem brain tissue

(2019) Sujan C. Das et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Autism-like social deficit generated by Dock4 deficiency is rescued by restoration of Rac1 activity and NMDA receptor function

(2019) Daji Guo et al.   MOLECULAR PSYCHIATRY

Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development

(2019) Cleber A. Trujillo et al.   Cell Stem Cell

High-throughput screen for compounds that modulate neurite growth of human induced pluripotent stem cell-derived neurons

(2018) Sean P. Sherman et al.   Disease Models & Mechanisms

Brain transcriptome databases: a user's guide

(2018) Jason M. Keil et al.   JOURNAL OF NEUROSCIENCE

Dendritic structural plasticity and neuropsychiatric disease

(2018) Marc P. Forrest et al.   NATURE REVIEWS NEUROSCIENCE

The effect of rho kinase inhibition on morphological and electrophysiological maturity in iPSC-derived neurons

(2018) Lise J. Harbom et al.   CELL AND TISSUE RESEARCH

Stem cell models of human synapse development and degeneration

(2018) Emily S. Wilson et al.   MOLECULAR BIOLOGY OF THE CELL

Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization

(2017) Brock Roberts et al.   MOLECULAR BIOLOGY OF THE CELL

Cell diversity and network dynamics in photosensitive human brain organoids

(2017) Giorgia Quadrato et al.   NATURE

Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons

(2017) Xiaoliang Xiang et al.   NEUROSCIENCE LETTERS

Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome

(2017) Alexander Pyronneau et al.   Science Signaling

Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome

(2017) Alexander Pyronneau et al.   Science Signaling

RhoGTPase Regulators Orchestrate Distinct Stages of Synaptic Development

(2017) Samuel Martin-Vilchez et al.   PLoS One

Multi-level characterization of balanced inhibitory-excitatory cortical neuron network derived from human pluripotent stem cells

(2017) Aishwarya G. Nadadhur et al.   PLoS One

Stem Cell Models of Human Brain Development

(2016) Iva Kelava et al.   Cell Stem Cell

Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways

(2016) Xiaoliang Xiang et al.   FEBS LETTERS

Spontaneous Neuronal Activity in Developing Neocortical Networks: From Single Cells to Large-Scale Interactions

(2016) Heiko J. Luhmann et al.   Frontiers in Neural Circuits

Non-muscle myosin II in disease: mechanisms and therapeutic opportunities

(2015) K. A. Newell-Litwa et al.   Disease Models & Mechanisms

ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity

(2015) Karen A. Newell-Litwa et al.   JOURNAL OF CELL BIOLOGY

Modulation of actin dynamics by Rac1 to target cognitive function

(2015) Maria V. Tejada-Simon   JOURNAL OF NEUROCHEMISTRY

Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database

(2015) Jinchen Li et al.   MOLECULAR PSYCHIATRY

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

(2015) Anca M Paşca et al.   NATURE METHODS

Prenatal Expression Patterns of Genes Associated With Neuropsychiatric Disorders

(2014) Rebecca Birnbaum et al.   AMERICAN JOURNAL OF PSYCHIATRY

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

Temporal Specification and Bilaterality of Human Neocortical Topographic Gene Expression

(2014) Mihovil Pletikos et al.   NEURON

The GABA excitatory/inhibitory developmental sequence: A personal journey

(2014) Y. Ben-Ari   NEUROSCIENCE

Electrical Compartmentalization in Dendritic Spines

(2013) Rafael Yuste   Annual Review of Neuroscience

Molecular mechanisms of dendrite stability

(2013) Anthony J. Koleske   NATURE REVIEWS NEUROSCIENCE

Simple buffers for 3D STORM microscopy

(2013) Nicolas Olivier et al.   Biomedical Optics Express

Modulation of dendritic spines and synaptic function by Rac1: A possible link to Fragile X syndrome pathology

(2011) Odelia Y.N. Bongmba et al.   BRAIN RESEARCH

Dysregulation of Rho GTPases in the αPix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and cognitive deficits

(2011) Ger J.A. Ramakers et al.   HUMAN MOLECULAR GENETICS

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Myosin IIB Activity and Phosphorylation Status Determines Dendritic Spine and Post-Synaptic Density Morphology

(2011) Jennifer L. Hodges et al.   PLoS One

Control of synapse development and plasticity by Rho GTPase regulatory proteins

(2011) Kimberley F. Tolias et al.   PROGRESS IN NEUROBIOLOGY

Actin in dendritic spines: connecting dynamics to function

(2010) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

(2009) Jeffrey J. Hutsler et al.   BRAIN RESEARCH

The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors

(2009) N. Nadif Kasri et al.   GENES & DEVELOPMENT

Molecular Architecture of Synaptic Actin Cytoskeleton in Hippocampal Neurons Reveals a Mechanism of Dendritic Spine Morphogenesis

(2009) Farida Korobova et al.   MOLECULAR BIOLOGY OF THE CELL

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Functional and Evolutionary Insights into Human Brain Development through Global Transcriptome Analysis

(2009) Matthew B. Johnson et al.   NEURON

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY