NLRC5 alleviated OGD/R-induced PC12-cell injury by inhibiting activation of the TLR4/MyD88/NF-κB pathway

Long non-coding RNA AK038897 aggravates cerebral ischemia/reperfusion injury via acting as a ceRNA for miR-26a-5p to target DAPK1

(2019) Rui Wei et al.   EXPERIMENTAL NEUROLOGY

NLRC5 negatively regulates LTA‐induced inflammation via TLR2/NF‐κB and participates in TLR2‐mediated allergic airway inflammation

(2019) Muzi Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Overexpression of miR‐224‐3p alleviates apoptosis from cerebral ischemia reperfusion injury by targeting FIP200

(2019) Yiming Deng et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

REDD1 knockdown protects H9c2 cells against myocardial ischemia/reperfusion injury through Akt/mTORC1/Nrf2 pathway-ameliorated oxidative stress: An in vitro study

(2019) Peng Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The neuroprotective effects of carvacrol on ischemia/reperfusion-induced hippocampal neuronal impairment by ferroptosis mitigation

(2019) Xueying Guan et al.   LIFE SCIENCES

Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro

(2019) Yichao Du et al.   Oxidative Medicine and Cellular Longevity

Knockdown of NLRC5 attenuates renal I/R injury in vitro through the activation of PI3K/Akt signaling pathway

(2018) Feng Han et al.   BIOMEDICINE & PHARMACOTHERAPY

Mitochondria in Ischemic Stroke: New Insight and Implications

(2018) Fan Liu et al.   Aging and Disease

Protective effects of dioscin against systemic inflammatory response syndromevia adjusting TLR2/MyD88/NF‑κb signal pathway

(2018) Xuerong Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Neuro-protective role of nanocapsulated curcumin against cerebral ischemia-reperfusion induced oxidative injury

(2018) Abhishek Mukherjee et al.   BRAIN RESEARCH

Salvianolic Acids for Injection (SAFI) suppresses inflammatory responses in activated microglia to attenuate brain damage in focal cerebral ischemia

(2017) Pengwei Zhuang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Eupatilin exerts neuroprotective effects in mice with transient focal cerebral ischemia by reducing microglial activation

(2017) Arjun Sapkota et al.   PLoS One

NLRC5 regulates TGF-β1-induced proliferation and activation of hepatic stellate cells during hepatic fibrosis

(2016) Tao Xu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Reversible ubiquitination shapes NLRC5 function and modulates NF-κB activation switch

(2015) Qingcai Meng et al.   JOURNAL OF CELL BIOLOGY

A feedforward loop of NLRC5 (de)ubiquitination keeps IKK–NF-κB in check

(2015) Yinling Hu   JOURNAL OF CELL BIOLOGY

Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70

(2015) Meng Qi et al.   PHARMACOLOGICAL RESEARCH

Unsolved Mysteries in NLR Biology

(2013) Christopher Lupfer et al.   Frontiers in Immunology

Lipid Peroxidative Damage on Cisplatin Exposure and Alterations in Antioxidant Defense System in Rat Kidneys: A Possible Protective Effect of Selenium

(2012) Branka I. Ognjanović et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

NLRC5 Negatively Regulates the NF-κB and Type I Interferon Signaling Pathways

(2010) Jun Cui et al.   CELL

NLRC5 Limits the Activation of Inflammatory Pathways

(2010) S. Benko et al.   JOURNAL OF IMMUNOLOGY

Stroke

(2008) Geoffrey A Donnan et al.   LANCET