Genetics of migraine aura: an update

Mitochondrial genome-wide association study of migraine – the HUNT Study

(2020) Sigrid Børte et al.   CEPHALALGIA

Migraine With Aura as Early Disease Marker in Hereditary Dutch-Type Cerebral Amyloid Angiopathy

(2020) Emma A. Koemans et al.   STROKE

Benefits and limitations of genome-wide association studies

(2019) Vivian Tam et al.   NATURE REVIEWS GENETICS

Advances in genetics of migraine

(2019) Heidi G. Sutherland et al.   JOURNAL OF HEADACHE AND PAIN

Genetic mouse models of migraine

(2019) Daniela Pietrobon et al.   JOURNAL OF HEADACHE AND PAIN

A causal role for TRESK loss of function in migraine mechanisms

(2019) Philippa Pettingill et al.   BRAIN

Increased Mortality and Vascular Phenotype in a Knock-In Mouse Model of Retinal Vasculopathy With Cerebral Leukoencephalopathy and Systemic Manifestations

(2019) Inge A. Mulder et al.   STROKE

First FHM3 mouse model shows spontaneous cortical spreading depolarizations

(2019) Nico A. Jansen et al.   Annals of Clinical and Translational Neurology

Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine

(2018) Zachary F. Gerring et al.   BMC GENOMICS

The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families

(2018) Marjo Eveliina Hiekkala et al.   CEPHALALGIA

Linking migraine frequency with family history of migraine

(2018) Nadine Pelzer et al.   CEPHALALGIA

Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition

(2018)   CEPHALALGIA

Clinical spectrum of hemiplegic migraine and chances of finding a pathogenic mutation

(2018) Nadine Pelzer et al.   NEUROLOGY

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

(2018) Padhraig Gormley et al.   NEURON

Analysis of shared heritability in common disorders of the brain

(2018) et al.   SCIENCE

RVCL-S and CADASIL display distinct impaired vascular function

(2018) Irene de Boer et al.   NEUROLOGY

Systemic features of retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations: a monogenic small vessel disease

(2018) N. Pelzer et al.   JOURNAL OF INTERNAL MEDICINE

Mitochondrial genetic medicine

(2018) Douglas C. Wallace   NATURE GENETICS

PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats

(2018) Juan Mo et al.   NEUROBIOLOGY OF DISEASE

Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK

(2018) Perrine Royal et al.   NEURON

A genetic risk score is differentially associated with migraine with and without aura

(2017) Claudia Pisanu et al.   HUMAN GENETICS

Migrainomics — identifying brain and genetic markers of migraine

(2017) Dale R. Nyholt et al.   Nature Reviews Neurology

Impaired K+ binding to glial glutamate transporter EAAT1 in migraine

(2017) Peter Kovermann et al.   Scientific Reports

Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations

(2016) Anine H. Stam et al.   BRAIN

Animal models of monogenic migraine

(2016) Shih-Pin Chen et al.   CEPHALALGIA

Prevalence and characteristics of migraine in CADASIL

(2016) Stephanie Guey et al.   CEPHALALGIA

Defective glutamate and K+clearance by cortical astrocytes in familial hemiplegic migraine type 2

(2016) Clizia Capuani et al.   EMBO Molecular Medicine

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

(2016) Padhraig Gormley et al.   NATURE GENETICS

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model

(2016) Pernille Bøttger et al.   Scientific Reports

Systematic re-evaluation of genes from candidate gene association studies in migraine using a large genome-wide association data set

(2015) Boukje de Vries et al.   CEPHALALGIA

Gene-based pleiotropy across migraine with aura and migraine without aura patient groups

(2015) Huiying Zhao et al.   CEPHALALGIA

Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation

(2015) Maroof Hasan et al.   IMMUNITY

Migraine pathophysiology: lessons from mouse models and human genetics

(2015) Michel D Ferrari et al.   LANCET NEUROLOGY

ClinVar: public archive of interpretations of clinically relevant variants

(2015) Melissa J. Landrum et al.   NUCLEIC ACIDS RESEARCH

Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies

(2014) Dale R Nyholt et al.   CEPHALALGIA

Nonmigraine-associated TRESK K+ channel variant C110R does not increase the excitability of trigeminal ganglion neurons

(2014) Zhaohua Guo et al.   JOURNAL OF NEUROPHYSIOLOGY

Mechanism underlying unaltered cortical inhibitory synaptic transmission in contrast with enhanced excitatory transmission in CaV2.1 knockin migraine mice

(2014) Dania Vecchia et al.   NEUROBIOLOGY OF DISEASE

PRRT2 and hemiplegic migraine: A complex association

(2014) N. Pelzer et al.   NEUROLOGY

Epigenetic mechanisms in migraine: a promising avenue?

(2013) Else Eising et al.   BMC Medicine

Studies on the Pathophysiology and Genetic Basis of Migraine

(2013) Claudia Gasparini et al.   CURRENT GENOMICS

PRRT2mutations and paroxysmal disorders

(2013) A. Méneret et al.   EUROPEAN JOURNAL OF NEUROLOGY

Role ofPRRT2in common paroxysmal neurological disorders: a gene with remarkable pleiotropy

(2013) Sarah E Heron et al.   JOURNAL OF MEDICAL GENETICS

Functional Analysis of a Migraine-Associated TRESK K+ Channel Mutation

(2013) P. Liu et al.   JOURNAL OF NEUROSCIENCE

Genome-wide meta-analysis identifies new susceptibility loci for migraine

(2013) Verneri Anttila et al.   NATURE GENETICS

Nonfunctional NaV1.1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects

(2013) S. Cestele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Casein Kinase I  Mutations in Familial Migraine and Advanced Sleep Phase

(2013) K. C. Brennan et al.   Science Translational Medicine

Calcium channels and migraine

(2012) Daniela Pietrobon   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Familial hemiplegic migraine type 1 mutations W1684R and V1696I alter G protein-mediated regulation of CaV2.1 voltage-gated calcium channels

(2012) Edgar Garza-López et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Familial and Sporadic Hemiplegic Migraine: Diagnosis and Treatment

(2012) Nadine Pelzer et al.   Current Treatment Options in Neurology

A possible role for mitochondrial dysfunction in migraine

(2012) S. Stuart et al.   MOLECULAR GENETICS AND GENOMICS

PRRT2 mutations in familial infantile seizures, paroxysmal dyskinesia, and hemiplegic migraine

(2012) C. Marini et al.   NEUROLOGY

Functional analysis of missense variants in the TRESK (KCNK18) K+ channel

(2012) Isabelle Andres-Enguix et al.   Scientific Reports

COL4A2 Mutations Impair COL4A1 and COL4A2 Secretion and Cause Hemorrhagic Stroke

(2011) Marion Jeanne et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Trigger factors for familial hemiplegic migraine

(2011) Jakob Møller Hansen et al.   CEPHALALGIA

Validation of the web-based LUMINA questionnaire for recruiting large cohorts of migraineurs

(2011) WPJ van Oosterhout et al.   CEPHALALGIA

Migraine: Role of the TRESK two-pore potassium channel

(2011) Ronald G. Lafrenière et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Increased Susceptibility to Cortical Spreading Depression in the Mouse Model of Familial Hemiplegic Migraine Type 2

(2011) Loredana Leo et al.   PLoS Genetics

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression

(2010) Katharina Eikermann-Haerter et al.   ANNALS OF NEUROLOGY

Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1

(2010) Verneri Anttila et al.   NATURE GENETICS

A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura

(2010) Ronald G Lafrenière et al.   NATURE MEDICINE

Defective membrane expression of the Na+-HCO3- cotransporter NBCe1 is associated with familial migraine

(2010) M. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

COL4A1 Mutations as a Monogenic Cause of Cerebral Small Vessel Disease

(2010) Silvia Lanfranconi et al.   STROKE

High cortical spreading depression susceptibility and migraine-associated symptoms in Cav2.1 S218L mice

(2009) Arn M. J. M. van den Maagdenberg et al.   ANNALS OF NEUROLOGY

Two Common Mitochondrial DNA Polymorphisms are Highly Associated with Migraine Headache and Cyclic Vomiting Syndrome

(2009) EA Zaki et al.   CEPHALALGIA

Enhanced Excitatory Transmission at Cortical Synapses as the Basis for Facilitated Spreading Depression in CaV2.1 Knockin Migraine Mice

(2009) Angelita Tottene et al.   NEURON

The hemiplegic migraine-associated Y1245C mutation in CACNA1A results in a gain of channel function due to its effect on the voltage sensor and G-protein-mediated inhibition

(2009) Selma A. Serra et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Cumulative Lifetime Migraine Incidence in Women and Men

(2008) WF Stewart et al.   CEPHALALGIA

A high-density association screen of 155 ion transport genes for involvement with common migraine

(2008) Dale R. Nyholt et al.   HUMAN MOLECULAR GENETICS

Diverse Functional Consequences of Mutations in the Na+/K+-ATPase α2-Subunit Causing Familial Hemiplegic Migraine Type 2

(2008) Neslihan N. Tavraz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Self-Limited Hyperexcitability: Functional Effect of a Familial Hemiplegic Migraine Mutation of the Nav1.1 (SCN1A) Na+ Channel

(2008) S. Cestele et al.   JOURNAL OF NEUROSCIENCE

The S218L familial hemiplegic migraine mutation promotes deinhibition of Cav2.1 calcium channels during direct G-protein regulation

(2008) Norbert Weiss et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY