Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer’s disease

Plasma P-tau181 in Alzheimer’s disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer’s dementia

(2020) Shorena Janelidze et al.   NATURE MEDICINE

Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration

(2020) Elisabeth H. Thijssen et al.   NATURE MEDICINE

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease

(2020) Nicolas R. Barthélemy et al.   NATURE MEDICINE

Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer’s disease

(2020) Shorena Janelidze et al.   Nature Communications

Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer’s disease and PET amyloid-positive patient identification

(2020) Nicolas R. Barthélemy et al.   Alzheimers Research & Therapy

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

(2019) Oliver Preische et al.   NATURE MEDICINE

The prognostic value of the Tau protein serum level in metastatic breast cancer patients and its correlation with brain metastases

(2019) Amélie Darlix et al.   BMC CANCER

Tau Phosphorylation Rates Measured by Mass Spectrometry Differ in the Intracellular Brain vs. Extracellular Cerebrospinal Fluid Compartments and Are Differentially Affected by Alzheimer’s Disease

(2019) Nicolas R. Barthélemy et al.   Frontiers in Aging Neuroscience

Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography

(2018) Michelle M. Mielke et al.   Alzheimers & Dementia

High performance plasma amyloid-β biomarkers for Alzheimer’s disease

(2018) Akinori Nakamura et al.   NATURE

Tau Kinetics in Neurons and the Human Central Nervous System

(2018) Chihiro Sato et al.   NEURON

Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer’s disease

(2018) Claudia Cicognola et al.   ACTA NEUROPATHOLOGICA

Increases of Plasma Levels of Glial Fibrillary Acidic Protein, Tau, and Amyloid β up to 90 Days after Traumatic Brain Injury

(2017) Tanya Bogoslovsky et al.   JOURNAL OF NEUROTRAUMA

Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer’s disease and down syndrome

(2017) Harutsugu Tatebe et al.   Molecular Neurodegeneration

Revisiting biomarker discovery by plasma proteomics

(2017) Philipp E Geyer et al.   Molecular Systems Biology

Review: Tau in biofluids - relation to pathology, imaging and clinical features

(2017) H. Zetterberg   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Association of Plasma Total Tau Level With Cognitive Decline and Risk of Mild Cognitive Impairment or Dementia in the Mayo Clinic Study on Aging

(2017) Michelle M. Mielke et al.   JAMA Neurology

Comparing Plasma Phospho Tau, Total Tau, and Phospho Tau–Total Tau Ratio as Acute and Chronic Traumatic Brain Injury Biomarkers

(2017) Richard Rubenstein et al.   JAMA Neurology

Increased levels of plasma total tau in adult Down syndrome

(2017) Takashi Kasai et al.   PLoS One

Tau Protein Quantification in Human Cerebrospinal Fluid by Targeted Mass Spectrometry at High Sequence Coverage Provides Insights into Its Primary Structure Heterogeneity

(2016) Nicolas R Barthélemy et al.   JOURNAL OF PROTEOME RESEARCH

Plasma tau in Alzheimer disease

(2016) Niklas Mattsson et al.   NEUROLOGY

Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases

(2016) Mehtap Bacioglu et al.   NEURON

Mass spectrometry follow-up of t181, s199, s202, t205, and T217 tau phosphorylation in cerebrospinal fluid from patients revealed a specific Alzheimer’s disease pattern

(2015) Nicolas Barthelemy et al.   Alzheimers & Dementia

Age and amyloid effects on human central nervous system amyloid-beta kinetics

(2015) Bruce W. Patterson et al.   ANNALS OF NEUROLOGY

Amyloid-β efflux from the central nervous system into the plasma

(2014) Kaleigh Filisa Roberts et al.   ANNALS OF NEUROLOGY

Longitudinal Change in CSF Biomarkers in Autosomal-Dominant Alzheimer's Disease

(2014) A. M. Fagan et al.   Science Translational Medicine

Olympic boxing is associated with elevated levels of the neuronal protein tau in plasma

(2013) Sanna Neselius et al.   BRAIN INJURY

Increased in Vivo Amyloid- 42 Production, Exchange, and Loss in Presenilin Mutation Carriers

(2013) R. Potter et al.   Science Translational Medicine

Plasma tau levels in Alzheimer's disease

(2013) Henrik Zetterberg et al.   Alzheimers Research & Therapy

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE