Obesity-induced excess of 17-hydroxyprogesterone promotes hyperglycemia through activation of glucocorticoid receptor

Oxysterols and nuclear receptors

(2019) Liqian Ma et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

17α-Hydroxyprogesterone Caproate and the Risk of Glucose Intolerance in Pregnancy

(2019) Ahizechukwu C. Eke et al.   OBSTETRICS AND GYNECOLOGY

Progestogens for the prevention of preterm birth and risk of developing gestational diabetes mellitus: a meta-analysis

(2019) Vasilios Pergialiotis et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Dexamethasone-induced Krüppel-like factor 9 expression promotes hepatic gluconeogenesis and hyperglycemia

(2019) Anfang Cui et al.   JOURNAL OF CLINICAL INVESTIGATION

A General Introduction to Glucocorticoid Biology

(2019) Steven Timmermans et al.   Frontiers in Immunology

Nuclear Receptor LRH-1 Functions to Promote Castration-Resistant Growth of Prostate Cancer via Its Promotion of Intratumoral Androgen Biosynthesis

(2018) Lijia Xiao et al.   CANCER RESEARCH

The significance of cholesterol and its metabolite, 27-hydroxycholesterol in breast cancer

(2018) Erik R. Nelson   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Causal Association of Overall Obesity and Abdominal Obesity with Type 2 Diabetes: A Mendelian Randomization Analysis

(2018) Tao Wang et al.   Obesity

Therapeutic Mechanisms of Glucocorticoids

(2018) Jolien Vandewalle et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Adipocyte Glucocorticoid Receptor Deficiency Promotes Adipose Tissue Expandability and Improves the Metabolic Profile Under Corticosterone Exposure

(2018) Héloïse Dalle et al.   DIABETES

Nutrient-sensing nuclear receptors PPARα and FXR control liver energy balance

(2017) Geoffrey A. Preidis et al.   JOURNAL OF CLINICAL INVESTIGATION

The glucocorticoid receptor: cause of or cure for obesity?

(2016) Kezia John et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Serum Dehydroepiandrosterone Sulfate and Risk for Type 2 Diabetes in Older Men and Women: The Pro.V.A Study

(2016) Nicola Veronese et al.   Canadian Journal of Diabetes

Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition

(2016) Kristina M. Mueller et al.   DIABETES

Impaired pancreatic beta cell compensatory function is the main cause of type 2 diabetes in individuals with high genetic risk: a 9 year prospective cohort study in the Chinese population

(2016) Jing Yan et al.   DIABETOLOGIA

Serum dehydroepiandrosterone levels are associated with lower risk of type 2 diabetes: the Rotterdam Study

(2016) Adela Brahimaj et al.   DIABETOLOGIA

Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation

(2016) Sandip K. Bose et al.   ENDOCRINOLOGY

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

(2016) Alexandra Montagner et al.   GUT

The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux

(2016) Varman T. Samuel et al.   JOURNAL OF CLINICAL INVESTIGATION

Common variants in or near ZNRF1, COLEC12, SCYL1BP1 and API5 are associated with diabetic retinopathy in Chinese patients with type 2 diabetes

(2015) Danfeng Peng et al.   DIABETOLOGIA

Hepatic estrogen receptor α improves hepatosteatosis through upregulation of small heterodimer partner

(2015) Xiaolin Wang et al.   JOURNAL OF HEPATOLOGY

11β-Hydroxysteroid dehydrogenase 1: Regeneration of active glucocorticoids is only part of the story

(2015) Alex Odermatt et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer

(2015) Zhenfei Li et al.   NATURE

Safety, efficacy and weight effect of two 11β-HSD1 inhibitors in metformin-treated patients with type 2 diabetes

(2014) T. Heise et al.   DIABETES OBESITY & METABOLISM

Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα

(2014) Yan Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of 17α-Hydroxyprogesterone Caproate on Glucose Intolerance in Pregnancy

(2014) Thaddeus P. Waters et al.   OBSTETRICS AND GYNECOLOGY

Cortisol, obesity, and the metabolic syndrome: A cross-sectional study of obese subjects and review of the literature

(2013) S.B. Abraham et al.   Obesity

Selective Insulin and Leptin Resistance in Metabolic Disorders

(2012) A. Christine Könner et al.   Cell Metabolism

Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy

(2012) Charles J. Ryan et al.   NEW ENGLAND JOURNAL OF MEDICINE

DAX1 suppresses FXR transactivity as a novel co-repressor

(2011) Jin Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants

(2011) Elahe A. Mostaghel et al.   CLINICAL CANCER RESEARCH

Abiraterone Acetate

(2011) Lily P.H. Yang   DRUGS

Abiraterone and Increased Survival in Metastatic Prostate Cancer

(2011) Johann S. de Bono et al.   NEW ENGLAND JOURNAL OF MEDICINE

17 α-Hydroxyprogesterone Caproate (Makena™)

(2011) Emma D. Deeks   PEDIATRIC DRUGS

Regulation of Hepatic Gluconeogenesis by an ER-Bound Transcription Factor, CREBH

(2010) Min-Woo Lee et al.   Cell Metabolism

Elevated Fasting Plasma Cortisol Is Associated with Ischemic Heart Disease and Its Risk Factors in People with Type 2 Diabetes: The Edinburgh Type 2 Diabetes Study

(2010) Rebecca M. Reynolds et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis

(2010) Sayeepriyadarshini Anakk et al.   JOURNAL OF CLINICAL INVESTIGATION

LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice

(2010) Rucha Patel et al.   JOURNAL OF CLINICAL INVESTIGATION

G protein-coupled receptor 48 upregulates estrogen receptor   expression via cAMP/PKA signaling in the male reproductive tract

(2009) X.-Y. Li et al.   DEVELOPMENT

The Glucocorticoid Receptor Controls Hepatic Dyslipidemia through Hes1

(2008) Ulrike Lemke et al.   Cell Metabolism

Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

(2007) Jie Zhou et al.   GASTROENTEROLOGY