Obesity-induced excess of 17-hydroxyprogesterone promotes hyperglycemia through activation of glucocorticoid receptor
出版年份 2020 全文链接
标题
Obesity-induced excess of 17-hydroxyprogesterone promotes hyperglycemia through activation of glucocorticoid receptor
作者
关键词
-
出版物
JOURNAL OF CLINICAL INVESTIGATION
Volume 130, Issue 7, Pages 3791-3804
出版商
American Society for Clinical Investigation
发表日期
2020-06-08
DOI
10.1172/jci134485
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Oxysterols and nuclear receptors
- (2019) Liqian Ma et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- 17α-Hydroxyprogesterone Caproate and the Risk of Glucose Intolerance in Pregnancy
- (2019) Ahizechukwu C. Eke et al. OBSTETRICS AND GYNECOLOGY
- Progestogens for the prevention of preterm birth and risk of developing gestational diabetes mellitus: a meta-analysis
- (2019) Vasilios Pergialiotis et al. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Dexamethasone-induced Krüppel-like factor 9 expression promotes hepatic gluconeogenesis and hyperglycemia
- (2019) Anfang Cui et al. JOURNAL OF CLINICAL INVESTIGATION
- A General Introduction to Glucocorticoid Biology
- (2019) Steven Timmermans et al. Frontiers in Immunology
- Nuclear Receptor LRH-1 Functions to Promote Castration-Resistant Growth of Prostate Cancer via Its Promotion of Intratumoral Androgen Biosynthesis
- (2018) Lijia Xiao et al. CANCER RESEARCH
- The significance of cholesterol and its metabolite, 27-hydroxycholesterol in breast cancer
- (2018) Erik R. Nelson MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Causal Association of Overall Obesity and Abdominal Obesity with Type 2 Diabetes: A Mendelian Randomization Analysis
- (2018) Tao Wang et al. Obesity
- Therapeutic Mechanisms of Glucocorticoids
- (2018) Jolien Vandewalle et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Adipocyte Glucocorticoid Receptor Deficiency Promotes Adipose Tissue Expandability and Improves the Metabolic Profile Under Corticosterone Exposure
- (2018) Héloïse Dalle et al. DIABETES
- Nutrient-sensing nuclear receptors PPARα and FXR control liver energy balance
- (2017) Geoffrey A. Preidis et al. JOURNAL OF CLINICAL INVESTIGATION
- The glucocorticoid receptor: cause of or cure for obesity?
- (2016) Kezia John et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Serum Dehydroepiandrosterone Sulfate and Risk for Type 2 Diabetes in Older Men and Women: The Pro.V.A Study
- (2016) Nicola Veronese et al. Canadian Journal of Diabetes
- Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition
- (2016) Kristina M. Mueller et al. DIABETES
- Impaired pancreatic beta cell compensatory function is the main cause of type 2 diabetes in individuals with high genetic risk: a 9 year prospective cohort study in the Chinese population
- (2016) Jing Yan et al. DIABETOLOGIA
- Serum dehydroepiandrosterone levels are associated with lower risk of type 2 diabetes: the Rotterdam Study
- (2016) Adela Brahimaj et al. DIABETOLOGIA
- Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation
- (2016) Sandip K. Bose et al. ENDOCRINOLOGY
- Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD
- (2016) Alexandra Montagner et al. GUT
- The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux
- (2016) Varman T. Samuel et al. JOURNAL OF CLINICAL INVESTIGATION
- Common variants in or near ZNRF1, COLEC12, SCYL1BP1 and API5 are associated with diabetic retinopathy in Chinese patients with type 2 diabetes
- (2015) Danfeng Peng et al. DIABETOLOGIA
- Hepatic estrogen receptor α improves hepatosteatosis through upregulation of small heterodimer partner
- (2015) Xiaolin Wang et al. JOURNAL OF HEPATOLOGY
- 11β-Hydroxysteroid dehydrogenase 1: Regeneration of active glucocorticoids is only part of the story
- (2015) Alex Odermatt et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer
- (2015) Zhenfei Li et al. NATURE
- Safety, efficacy and weight effect of two 11β-HSD1 inhibitors in metformin-treated patients with type 2 diabetes
- (2014) T. Heise et al. DIABETES OBESITY & METABOLISM
- Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα
- (2014) Yan Lu et al. JOURNAL OF CLINICAL INVESTIGATION
- Effect of 17α-Hydroxyprogesterone Caproate on Glucose Intolerance in Pregnancy
- (2014) Thaddeus P. Waters et al. OBSTETRICS AND GYNECOLOGY
- Cortisol, obesity, and the metabolic syndrome: A cross-sectional study of obese subjects and review of the literature
- (2013) S.B. Abraham et al. Obesity
- Selective Insulin and Leptin Resistance in Metabolic Disorders
- (2012) A. Christine Könner et al. Cell Metabolism
- Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy
- (2012) Charles J. Ryan et al. NEW ENGLAND JOURNAL OF MEDICINE
- DAX1 suppresses FXR transactivity as a novel co-repressor
- (2011) Jin Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants
- (2011) Elahe A. Mostaghel et al. CLINICAL CANCER RESEARCH
- Abiraterone Acetate
- (2011) Lily P.H. Yang DRUGS
- Abiraterone and Increased Survival in Metastatic Prostate Cancer
- (2011) Johann S. de Bono et al. NEW ENGLAND JOURNAL OF MEDICINE
- 17 α-Hydroxyprogesterone Caproate (Makena™)
- (2011) Emma D. Deeks PEDIATRIC DRUGS
- Regulation of Hepatic Gluconeogenesis by an ER-Bound Transcription Factor, CREBH
- (2010) Min-Woo Lee et al. Cell Metabolism
- Elevated Fasting Plasma Cortisol Is Associated with Ischemic Heart Disease and Its Risk Factors in People with Type 2 Diabetes: The Edinburgh Type 2 Diabetes Study
- (2010) Rebecca M. Reynolds et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis
- (2010) Sayeepriyadarshini Anakk et al. JOURNAL OF CLINICAL INVESTIGATION
- LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice
- (2010) Rucha Patel et al. JOURNAL OF CLINICAL INVESTIGATION
- G protein-coupled receptor 48 upregulates estrogen receptor expression via cAMP/PKA signaling in the male reproductive tract
- (2009) X.-Y. Li et al. DEVELOPMENT
- The Glucocorticoid Receptor Controls Hepatic Dyslipidemia through Hes1
- (2008) Ulrike Lemke et al. Cell Metabolism
- Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis
- (2007) Jie Zhou et al. GASTROENTEROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now