FTY720 reactivates cryptococcal granulomas in mice through S1P receptor 3 on macrophages

Macrophage heterogeneity and plasticity in tuberculosis

(2019) Arshad Khan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Acylhydrazones as Antifungal Agents Targeting the Synthesis of Fungal Sphingolipids

(2018) Cristina Lazzarini et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Sphingosine-1-phosphate receptors and innate immunity

(2018) Arielle M. Bryan et al.   CELLULAR MICROBIOLOGY

Reactivation of dormant/latent fungal infection

(2018) Kevin Brunet et al.   JOURNAL OF INFECTION

The Role of Phospholipase C Signaling in Macrophage-Mediated Inflammatory Response

(2018) Liqian Zhu et al.   Journal of Immunology Research

Mechanisms of Cryptococcus neoformans-Mediated Host Damage

(2018) Arturo Casadevall et al.   Frontiers in Immunology

Sphingosine 1-phosphate receptor subtype 3 (S1P3) contributes to brain injury after transient focal cerebral ischemia via modulating microglial activation and their M1 polarization

(2018) Bhakta Prasad Gaire et al.   Journal of Neuroinflammation

Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy

(2018) Rui-zhen Sun et al.   Biomed Research International

S1P/S1PR3 axis promotes aerobic glycolysis by YAP/c-MYC/PGAM1 axis in osteosarcoma

(2018) Yifei Shen et al.   EBioMedicine

Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis

(2017) Radha Rajasingham et al.   LANCET INFECTIOUS DISEASES

Fingolimod Protects Against Ischemic White Matter Damage by Modulating Microglia Toward M2 Polarization via STAT3 Pathway

(2017) Chuan Qin et al.   STROKE

Differential S1P Receptor Profiles on M1- and M2-Polarized Macrophages Affect Macrophage Cytokine Production and Migration

(2017) Jan Müller et al.   Biomed Research International

The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration

(2016) Sofia Anastasiadou et al.   EXPERIMENTAL NEUROLOGY

Disseminated Cryptococcosis in a 63-year-old Patient with Multiple Sclerosis Treated with Fingolimod

(2016) Hiroyuki Seto et al.   INTERNAL MEDICINE

Immunologic mechanisms of fingolimod and the role of immunosenescence in the risk of cryptococcal infection: A case report and review of literature

(2016) Elena Grebenciucova et al.   Multiple Sclerosis and Related Disorders

Cryptococcal meningitis after fingolimod discontinuation in a patient with multiple sclerosis

(2016) Melanie D. Ward et al.   Multiple Sclerosis and Related Disorders

The Granuloma Response Controlling Cryptococcosis in Mice Depends on the Sphingosine Kinase 1–Sphingosine 1-Phosphate Pathway

(2015) Amir M. Farnoud et al.   INFECTION AND IMMUNITY

The Role of Cryptococcus in the Immune System of Pulmonary Cryptococcosis Patients

(2015) Jinlin Wang et al.   PLoS One

Introduction of Zinc-salt Fixation for Effective Detection of Immune Cell–related Markers by Immunohistochemistry

(2015) Hidetoshi Mori et al.   TOXICOLOGIC PATHOLOGY

Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin

(2015) Claudia Nussbaum et al.   Nature Communications

Novel Markers to Delineate Murine M1 and M2 Macrophages

(2015) Kyle A. Jablonski et al.   PLoS One

Cardiac and vascular effects of fingolimod: Mechanistic basis and clinical implications

(2014) John Camm et al.   AMERICAN HEART JOURNAL

An update on the biology of sphingosine 1-phosphate receptors

(2014) Victoria A. Blaho et al.   JOURNAL OF LIPID RESEARCH

Sphingolipid metabolites in inflammatory disease

(2014) Michael Maceyka et al.   NATURE

Intravascular staining for discrimination of vascular and tissue leukocytes

(2014) Kristin G Anderson et al.   Nature Protocols

Knock Out of S1P3 Receptor Signaling Attenuates Inflammation and Fibrosis in Bleomycin-Induced Lung Injury Mice Model

(2014) Ken Murakami et al.   PLoS One

Circulating Monocytes Are Reduced by Sphingosine-1-Phosphate Receptor Modulators Independently of S1P3

(2013) N. D. Lewis et al.   JOURNAL OF IMMUNOLOGY

Epidemiology of Cryptococcal Meningitis in the US: 1997–2009

(2013) Vasilios Pyrgos et al.   PLoS One

Discovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator

(2013) Shifeng Pan et al.   ACS Medicinal Chemistry Letters

The selective sphingosine 1-phosphate receptor modulator BAF312 redirects lymphocyte distribution and has species-specific effects on heart rate

(2012) P Gergely et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Brief History of IL-9

(2011) R. Goswami et al.   JOURNAL OF IMMUNOLOGY

Paradoxical roles of alveolar macrophages in the host response to Cryptococcus neoformans

(2011) Travis J. McQuiston et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Role of sphingosine-1-phosphate (S1P) and S1P receptor 2 in the phagocytosis of Cryptococcus neoformans by alveolar macrophages

(2011) T. McQuiston et al.   MICROBIOLOGY-SGM

Sphingosine 1-phosphate in coagulation and inflammation

(2011) Hideru Obinata et al.   Seminars in Immunopathology

Translational aspects of sphingosine 1-phosphate biology

(2011) Susan Pyne et al.   TRENDS IN MOLECULAR MEDICINE

Pulmonary Infection with an Interferon-γ-Producing Cryptococcus neoformans Strain Results in Classical Macrophage Activation and Protection

(2010) Sarah E. Hardison et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of Host Sphingosine Kinase 1 in the Lung Response against Cryptococcosis

(2010) T. McQuiston et al.   INFECTION AND IMMUNITY

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

(2010) Volker Brinkmann et al.   NATURE REVIEWS DRUG DISCOVERY

Role of Dendritic Cells and Alveolar Macrophages in Regulating Early Host Defense against Pulmonary Infection with Cryptococcus neoformans

(2009) J. J. Osterholzer et al.   INFECTION AND IMMUNITY

Selective activation of G alpha i mediated signalling of S1P3 by FTY720-phosphate

(2008) Sven-Christian Sensken et al.   CELLULAR SIGNALLING

Inheritance of Immune Polarization Patterns Is Linked to Resistance versus Susceptibility to Cryptococcus neoformans in a Mouse Model

(2008) G.-h. Chen et al.   INFECTION AND IMMUNITY

Evidence of a Role for Monocytes in Dissemination and Brain Invasion by Cryptococcus neoformans

(2008) C. Charlier et al.   INFECTION AND IMMUNITY