The aryl hydrocarbon receptor ligand ITE inhibits cell proliferation and migration and enhances sensitivity to drug‐resistance in hepatocellular carcinoma

The neuroprotective action of 3,3′-diindolylmethane against ischemia involves an inhibition of apoptosis and autophagy that depends on HDAC and AhR/CYP1A1 but not ERα/CYP19A1 signaling

(2019) J. Rzemieniec et al.   APOPTOSIS

Anti-tumor properties of methoxylated analogues of resveratrol in malignant MCF-7 but not in non-tumorigenic MCF-10A mammary epithelial cell lines

(2019) Annick D. van den Brand et al.   TOXICOLOGY

Outcomes and Quality of Life of Systemic Therapy in Advanced Hepatocellular Carcinoma

(2019) Kehua Zhou et al.   Cancers

Aryl hydrocarbon receptor (AHR): From selected human target genes and crosstalk with transcription factors to multiple AHR functions

(2019) Karl Walter Bock   BIOCHEMICAL PHARMACOLOGY

Aryl hydrocarbon receptor enhances the expression of miR-150-5p to suppress in prostate cancer progression by regulating MAP3K12

(2018) Jingsong Yu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

AhR ligand aminoflavone suppresses α6-integrin-Src-Akt signaling to attenuate tamoxifen resistance in breast cancer cells

(2018) Petreena S. Campbell et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Indole-3-carbinol induces G1 cell cycle arrest and apoptosis through aryl hydrocarbon receptor in THP-1 monocytic cell line

(2017) Saeed Mohammadi et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Aryl hydrocarbon receptor (AHR): “pioneer member” of the basic-helix/loop/helix per - Arnt - sim (bHLH/PAS) family of “sensors” of foreign and endogenous signals

(2017) Daniel W. Nebert   PROGRESS IN LIPID RESEARCH

Quantitative proteomics and phosphoproteomics on serial tumor biopsies from a sorafenib-treated HCC patient

(2016) Eva Dazert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt-mediated phosphorylation of Oct4 is associated with the proliferation of stem-like cancer cells

(2015) QING-WEI ZHAO et al.   ONCOLOGY REPORTS

Tryptophan derivatives regulate the transcription of Oct4 in stem-like cancer cells

(2015) Jie Cheng et al.   Nature Communications

MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway

(2015) Changjun He et al.   Oncotarget

Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cells

(2014) Joseph A Caruso et al.   CELL CYCLE

Inhibition of Akt Reverses the Acquired Resistance to Sorafenib by Switching Protective Autophagy to Autophagic Cell Death in Hepatocellular Carcinoma

(2014) B. Zhai et al.   MOLECULAR CANCER THERAPEUTICS

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) inhibits human ovarian cancer cell proliferation

(2014) Yan Li et al.   CELLULAR ONCOLOGY

An endogenous aryl hydrocarbon receptor ligand inhibits proliferation and migration of human ovarian cancer cells

(2013) Kai Wang et al.   CANCER LETTERS

3,3′-Diindolylmethane rapidly and selectively inhibits hepatocyte growth factor/c-Met signaling in breast cancer cells

(2013) Holly L. Nicastro et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Role of the Aryl Hydrocarbon Receptor in Carcinogenesis and Potential as a Drug Target

(2013) Stephen Safe et al.   TOXICOLOGICAL SCIENCES

Recent progress in understanding, diagnosing, and treating hepatocellular carcinoma

(2012) Mary Maluccio et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Long-term exposure to sorafenib of liver cancer cells induces resistance with epithelial-to-mesenchymal transition, increased invasion and risk of rebound growth

(2012) Hannah van Malenstein et al.   CANCER LETTERS

Malignant Transformation of Mammary Epithelial Cells by Ectopic Overexpression of the Aryl Hydrocarbon Receptor

(2012) J. Brooks et al.   CURRENT CANCER DRUG TARGETS

Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo

(2011) Huanjie Shao et al.   JOURNAL OF HEPATOLOGY

Activation of Phosphatidylinositol 3-Kinase/Akt Signaling Pathway Mediates Acquired Resistance to Sorafenib in Hepatocellular Carcinoma Cells

(2011) K.-F. Chen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Activation of the Aryl Hydrocarbon Receptor by TCDD Inhibits Mammary Tumor Metastasis in a Syngeneic Mouse Model of Breast Cancer

(2011) Tao Wang et al.   TOXICOLOGICAL SCIENCES

Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor

(2011) Michael S. Denison et al.   TOXICOLOGICAL SCIENCES

Aryl Hydrocarbon Receptor Functions as a Potent Coactivator of E2F1-Dependent Trascription Activity

(2010) Yuichi Watabe et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Molecular mechanisms of the physiological functions of the aryl hydrocarbon (dioxin) receptor, a multifunctional regulator that senses and responds to environmental stimuli

(2010) Yoshiaki FUJII-KURIYAMA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

(2010) F. J. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Aryl Hydrocarbon Receptor Functions as a Tumor Suppressor of Liver Carcinogenesis

(2009) Y. Fan et al.   CANCER RESEARCH

Activation of the Aryl-Hydrocarbon Receptor Inhibits Invasive and Metastatic Features of Human Breast Cancer Cells and Promotes Breast Cancer Cell Differentiation

(2009) Julie M. Hall et al.   MOLECULAR ENDOCRINOLOGY

Aryl Hydrocarbon Receptor Regulates Cell Cycle Progression in Human Breast Cancer Cells via a Functional Interaction with Cyclin-Dependent Kinase 4

(2009) M. A. Barhoover et al.   MOLECULAR PHARMACOLOGY