Nomilin targets the Keap1‐Nrf2 signalling and ameliorates the development of osteoarthritis

Therapeutic options for targeting inflammatory osteoarthritis pain

(2019) Philip G. Conaghan et al.   Nature Reviews Rheumatology

Osteoarthritis year in review 2018: genetics and epigenetics

(2018) M.A. Jeffries   OSTEOARTHRITIS AND CARTILAGE

Citrus nomilin down-regulates TNF-α-induced proliferation of aortic smooth muscle cells via apoptosis and inhibition of IκB

(2017) Jinhee Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Microbiome and Bone and Joint Disease

(2017) Christopher J. Hernandez   Current Rheumatology Reports

Kaempferol Alleviates the Interleukin-1β-Induced Inflammation in Rat Osteoarthritis Chondrocytes via Suppression of NF-κB

(2017) Zhengling Zhuang et al.   MEDICAL SCIENCE MONITOR

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Osteoarthritis: from pathogenic mechanisms and recent clinical developments to novel prospective therapeutic options

(2016) Claire Vinatier et al.   DRUG DISCOVERY TODAY

Paeonol Suppresses Neuroinflammatory Responses in LPS-Activated Microglia Cells

(2016) Li Xia He et al.   INFLAMMATION

ADAM and ADAMTS Family Proteins and Snake Venom Metalloproteinases: A Structural Overview

(2016) Soichi Takeda   Toxins

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

(2015) Joanna D. Wardyn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Molecular basis of the Keap1–Nrf2 system

(2015) Takafumi Suzuki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sulforaphane Attenuates Muscle Inflammation in Dystrophin-deficientmdxMice via NF-E2-related Factor 2 (Nrf2)-mediated Inhibition of NF-κB Signaling Pathway

(2015) Cheng-Cao Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoarthritis

(2015) S Glyn-Jones et al.   LANCET

Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis

(2015) Dawei Cai et al.   ARTHRITIS RESEARCH & THERAPY

Redox activation of Nrf2 & NF-κB: A double end sword?

(2013) Mabel Buelna-Chontal et al.   CELLULAR SIGNALLING

Nomilin inhibits tumor-specific angiogenesis by downregulating VEGF, NO and proinflammatory cytokine profile and also by inhibiting the activation of MMP-2 and MMP-9

(2011) Poyil Pratheeshkumar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

What's new in our understanding of the role of adipokines in rheumatic diseases?

(2011) Rodolfo Gómez et al.   Nature Reviews Rheumatology

Prevalence of symptomatic hip and knee osteoarthritis: a two-phase population-based survey1

(2011) F. Guillemin et al.   OSTEOARTHRITIS AND CARTILAGE

NF-κB Signaling: Multiple Angles to Target OA

(2010) Kenneth B. Marcu et al.   CURRENT DRUG TARGETS

Activation of calcium/calmodulin-dependent protein kinase IV and peroxisome proliferator-activated receptor γ coactivator-1α signaling pathway protects against neuronal injury and promotes mitochondrial biogenesis in the hippocampal CA1 subfield after tra

(2010) Shang-Der Chen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix

(2009) R.F. Loeser   OSTEOARTHRITIS AND CARTILAGE

A systems biology perspective on Nrf2-mediated antioxidant response

(2009) Qiang Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis

(2009) Constanze Csaki et al.   ARTHRITIS RESEARCH & THERAPY