Astragaloside IV alleviates mouse slow transit constipation by modulating gut microbiota profile and promoting butyric acid generation

Extract from Astragalus membranaceus inhibit breast cancer cells proliferation via PI3K/AKT/mTOR signaling pathway

(2018) Ruijuan Zhou et al.   BMC Complementary and Alternative Medicine

Human gut microbiome: hopes, threats and promises

(2018) Patrice D Cani   GUT

OUP accepted manuscript

(2018)   Gastroenterology Report

Astragaloside IV reversed the autophagy and oxidative stress induced by the intestinal microbiota of AIS in mice

(2018) Nan Xu et al.   JOURNAL OF MICROBIOLOGY

Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome

(2018) Arnau Vich Vila et al.   Science Translational Medicine

Astragaloside IV from Astragalus membranaceus ameliorates renal interstitial fibrosis by inhibiting inflammation via TLR4/NF-кB in vivo and in vitro

(2017) Xiangjun Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Astragaloside IV inhibits breast cancer cell invasion by suppressing Vav3 mediated Rac1/MAPK signaling

(2017) Ke Jiang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Bifidobacterium adolescentis Exerts Strain-Specific Effects on Constipation Induced by Loperamide in BALB/c Mice

(2017) Linlin Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Astragalus membranaceus-Polysaccharides Ameliorates Obesity, Hepatic Steatosis, Neuroinflammation and Cognition Impairment without Affecting Amyloid Deposition in Metabolically Stressed APPswe/PS1dE9 Mice

(2017) Yung-Cheng Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant

(2017) Ning Wang et al.   Oxidative Medicine and Cellular Longevity

Vascular protective effects of Astragalus membranaceus and its main constituents in rats with chronic hyperhomocysteinemia

(2017) Li-Hong Qiu et al.   Experimental and Therapeutic Medicine

Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic

(2017) Ping Liu et al.   Aging and Disease

Astragaloside-IV prevents acute kidney injury and inflammation by normalizing muscular mitochondrial function associated with a nitric oxide protective mechanism in crush syndrome rats

(2017) Isamu Murata et al.   Annals of Intensive Care

Chronic constipation

(2017) Michael Camilleri et al.   Nature Reviews Disease Primers

Unveiling the gut microbiota composition and functionality associated with constipation through metagenomic analyses

(2017) Leonardo Mancabelli et al.   Scientific Reports

Effects of taurine on gut microbiota and metabolism in mice

(2016) Haining Yu et al.   AMINO ACIDS

Research review on the pharmacological effects of astragaloside IV

(2016) Lei Li et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

(2016) Thibaut Duparc et al.   GUT

Gut microbial and short-chain fatty acid profiles in adults with chronic constipation before and after treatment with lubiprostone

(2015) Dae-Wook Kang et al.   ANAEROBE

The gut microbiome in health and in disease

(2015) Andrew B. Shreiner et al.   CURRENT OPINION IN GASTROENTEROLOGY

Understanding the Pathogenesis of Slow-Transit Constipation: One Step Forward

(2015) Hanlin L. Wang   DIGESTIVE DISEASES AND SCIENCES

Effect ofLactobacillus plantarumNCU116 on loperamide-induced constipation in mice

(2015) Chuan Li et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Disposition of Astragaloside IV via Enterohepatic Circulation Is Affected by the Activity of the Intestinal Microbiome

(2015) Yi Jin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Risk of developing colorectal cancer and benign colorectal neoplasm in patients with chronic constipation

(2014) A. Guérin et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The PTEN/PI3K/Akt signaling pathway mediates HMGB1-induced cell proliferation by regulating the NF-κB/cyclin D1 pathway in mouse mesangial cells

(2014) Xiao-Juan Feng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Astragalus saponins modulates colon cancer development by regulating calpain-mediated glucose-regulated protein expression

(2014) Yue Wang et al.   BMC Complementary and Alternative Medicine

NF-κB Inhibitory Activity of Sucrose Fatty Acid Esters and Related Constituents from Astragalus membranaceus

(2013) Wei Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Diagnosis and treatment of chronic constipation - a European perspective

(2011) J. Tack et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Hydrogen Sulfide, a Gaseous Transmitter, Stimulates Proliferation of Interstitial Cells of Cajal via Phosphorylation of AKT Protein Kinase

(2010) Ying Huang et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract

(2009) Pedro J. Gomez-Pinilla et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Loss of intramuscular and submuscular interstitial cells of Cajal and associated enteric nerves is related to decreased gastric emptying in streptozotocin-induced diabetes

(2009) x-y. wang et al.   NEUROGASTROENTEROLOGY AND MOTILITY