Targeting lipid droplet lysophosphatidylcholine for cisplatin chemotherapy

An Updated Review of Lysophosphatidylcholine Metabolism in Human Diseases

(2019) Shi-Hui Law et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epithelial ovarian cancer: Evolution of management in the era of precision medicine

(2019) Stephanie Lheureux et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Increase Paclitaxel Sensitivity to Better Suppress Serous Epithelial Ovarian Cancer via Ablating Androgen Receptor/Aryl Hydrocarbon Receptor-ABCG2 Axis

(2019) Wei-Min Chung et al.   Cancers

Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages

(2019) Daniel J. Greenwood et al.   SCIENCE

Preclinical evaluation of exemestane as a novel chemotherapy for gastric cancer

(2019) Juan‐Cheng Yang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

LDLR-mediated lipidome–transcriptome reprogramming in cisplatin insensitivity

(2019) Wei-Chun Chang et al.   ENDOCRINE-RELATED CANCER

Phospholipid Remodeling and Cholesterol Availability Regulate Intestinal Stemness and Tumorigenesis

(2018) Bo Wang et al.   Cell Stem Cell

Modulation of Hepatic MRP3/ABCC3 by Xenobiotics and Pathophysiological Conditions: Role in Drug Pharmacokinetics.

(2018) Carolina I. Ghanem et al.   CURRENT MEDICINAL CHEMISTRY

Emerging role of lipid metabolism alterations in Cancer stem cells

(2018) Mei Yi et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance

(2018) Alexia Karen Cotte et al.   Nature Communications

Mitochondrial Acetyl-CoA Synthetase 3 is Biosignature of Gastric Cancer Progression

(2018) Wei-Chun Chang et al.   Cancer Medicine

Influence of PEG coating on the biodistribution and tumor accumulation of pH-sensitive liposomes

(2018) Shirleide Santos Nunes et al.   Drug Delivery and Translational Research

Active Targeting of Drugs and Bioactive Molecules via Oral Administration by Ligand-Conjugated Lipidic Nanocarriers: Recent Advances

(2018) A. B. Shreya et al.   AAPS PHARMSCITECH

Comprehensive review on how platinum- and taxane-based chemotherapy of ovarian cancer affects biology of normal cells

(2018) Justyna Mikuła-Pietrasik et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

From yeast to humans - roles of the Kennedy pathway for phosphatidylcholine synthesis

(2017) Christopher R. McMaster   FEBS LETTERS

ω-3 polyunsaturated fatty acids direct differentiation of the membrane phenotype in mesenchymal stem cells to potentiate osteogenesis

(2017) Kandice R. Levental et al.   Science Advances

Construction of Nanodroplet/Adiposome and Artificial Lipid Droplets

(2016) Yang Wang et al.   ACS Nano

Impaired biosynthesis of the non-bilayer lipids phosphatidylethanolamine or cardiolipin does not affect peroxisome biogenesis and proliferation in Saccharomyces cerevisiae

(2016) Adam Kawałek et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cisplatin resistance and opportunities for precision medicine

(2016) Lauren Amable   PHARMACOLOGICAL RESEARCH

Cholesterol import and steroidogenesis are biosignatures for gastric cancer patient survival

(2016) Wei-Chun Chang et al.   Oncotarget

Evaluation of Extrusion Technique for Nanosizing Liposomes

(2016) Sandy Ong et al.   Pharmaceutics

Quantitative evaluation of cellular uptake, DNA incorporation and adduct formation in cisplatin sensitive and resistant cell lines: Comparison of different Pt-containing drugs

(2015) M. Corte-Rodríguez et al.   BIOCHEMICAL PHARMACOLOGY

An automated shotgun lipidomics platform for high throughput, comprehensive, and quantitative analysis of blood plasma intact lipids

(2015) Michal A. Surma et al.   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

DriverDBv2: a database for human cancer driver gene research

(2015) I-Fang Chung et al.   NUCLEIC ACIDS RESEARCH

Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma

(2015) Fabienne Guillaumond et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Second-line chemotherapy in advanced biliary cancer: a systematic review

(2014) A. Lamarca et al.   ANNALS OF ONCOLOGY

Two different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage

(2014) Christine Moessinger et al.   BMC CELL BIOLOGY

Androgen receptor enhances cell adhesion and decreases cell migration via modulating β1-integrin-AKT signaling in hepatocellular carcinoma cells

(2014) Wen-Lung Ma et al.   CANCER LETTERS

Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors

(2013) Su Chul Jang et al.   ACS Nano

Microarray-based detection and expression analysis of ABC and SLC transporters in drug-resistant ovarian cancer cell lines

(2013) Radosław Januchowski et al.   BIOMEDICINE & PHARMACOTHERAPY

Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis

(2013) Maite Martínez-Uña et al.   HEPATOLOGY

DriverDB: an exome sequencing database for cancer driver gene identification

(2013) Wei-Chung Cheng et al.   NUCLEIC ACIDS RESEARCH

Resistance to DNA-damaging treatment in non-small cell lung cancer tumor-initiating cells involves reduced DNA-PK/ATM activation and diminished cell cycle arrest

(2013) L Lundholm et al.   Cell Death & Disease

Comparative studies of polyethylene glycol-modified liposomes prepared using different PEG-modification methods

(2012) Koji Nakamura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Membrane Transporters as Determinants of the Pharmacology of Platinum Anticancer Drugs

(2012) Johnson J. Liu et al.   CURRENT CANCER DRUG TARGETS

Hepatic androgen receptor suppresses hepatocellular carcinoma metastasis through modulation of cell migration and anoikis

(2012) Wen-Lung Ma et al.   HEPATOLOGY

Signaling in Control of Cell Growth and Metabolism

(2012) P. S. Ward et al.   Cold Spring Harbor Perspectives in Biology

Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-β production

(2011) Hitoshi Hasegawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human Lysophosphatidylcholine Acyltransferases 1 and 2 Are Located in Lipid Droplets Where They Catalyze the Formation of Phosphatidylcholine

(2011) Christine Moessinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane lipidome of an epithelial cell line

(2011) Julio L. Sampaio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression through reactive oxygen species generation and ERK1/2 activation in 3T3-L1 adipocytes

(2010) Akihiko Kuniyasu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

The Kennedy pathway-De novo synthesis of phosphatidylethanolamine and phosphatidylcholine

(2010) Federica Gibellini et al.   IUBMB LIFE

Phosphatidylethanolamine synthesized by three different pathways is supplied to peroxisomes of the yeast Saccharomyces cerevisiae

(2009) Sabine Rosenberger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Genetic Variants in Phosphatidylethanolamine N-methyltransferase and Methylenetetrahydrofolate Dehydrogenase Influence Biomarkers of Choline Metabolism When Folate Intake Is Restricted

(2009) Alexandre Ivanov et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Peroxisome dependency of alkyl-containing GPI-anchor biosynthesis in the endoplasmic reticulum

(2009) N. Kanzawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry

(2009) C. S. Ejsing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA