Nuclear myosins – roles for molecular transporters and anchors

Nuclear actin regulates inducible transcription by enhancing RNA polymerase II clustering

(2020) Mian Wei et al.   Science Advances

Cytoskeletal proteins in the cell nucleus: a special nuclear actin perspective

(2019) Piergiorgio Percipalle et al.   MOLECULAR BIOLOGY OF THE CELL

Competition between two high- and low-affinity protein-binding sites in myosin VI controls its cellular function.

(2019) Natalia Fili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear actin dynamics in gene expression and genome organization

(2019) Salla Kyheröinen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

GPCR-induced calcium transients trigger nuclear actin assembly for chromatin dynamics

(2019) Ying Wang et al.   Nature Communications

Unconventional Myosins: How Regulation Meets Function

(2019) Natalia Fili et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Application of the SSB biosensor to study in vitro transcription

(2018) Alexander Cook et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The response to DNA damage in heterochromatin domains

(2018) Anna Fortuny et al.   CHROMOSOMA

Myosin‐1C uses a novel phosphoinositide‐dependent pathway for nuclear localization

(2018) Ilja Nevzorov et al.   EMBO REPORTS

Human Papilloma Virus and Autophagy

(2018) Domenico Mattoscio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Role for Myosin Va in Human Cytomegalovirus Nuclear Egress

(2018) Adrian R. Wilkie et al.   JOURNAL OF VIROLOGY

Nuclear myosin 1 associates with papillomavirus E2 regulatory protein and influences viral replication

(2018) Eve Sankovski et al.   VIROLOGY

Nuclear myosin/actin-motored contact between homologous chromosomes is initiated by ATM kinase and homology-directed repair proteins at double-strand DNA breaks to suppress chromosome rearrangements

(2018) Viktoria N. Evdokimova et al.   Oncotarget

Myosin VI in the nucleus of neurosecretory PC12 cells: Stimulation-dependent nuclear translocation and interaction with nuclear proteins

(2018) Lukasz Majewski et al.   Nucleus

Myosin VI in the nucleus of neurosecretory PC12 cells: Stimulation-dependent nuclear translocation and interaction with nuclear proteins

(2018) Lukasz Majewski et al.   Nucleus

Nuclear F-actin and myosins drive relocalization of heterochromatic breaks

(2018) Christopher P. Caridi et al.   NATURE

Coordination of DNA single strand break repair

(2017) Rachel Abbotts et al.   FREE RADICAL BIOLOGY AND MEDICINE

F-actin organizes the nucleus

(2017) Henna M. Moore et al.   NATURE CELL BIOLOGY

Ca 2+ -Induced Rigidity Change of the Myosin VIIa IQ Motif-Single α Helix Lever Arm Extension

(2017) Jianchao Li et al.   STRUCTURE

Human papillomavirus type 8 E7 protein binds nuclear myosin 1c and downregulates the expression of pre-rRNA

(2017) Evelyn Oswald et al.   VIRUS GENES

NDP52 activates nuclear myosin VI to enhance RNA polymerase II transcription

(2017) Natalia Fili et al.   Nature Communications

DNA double-strand break repair: a tale of pathway choices

(2016) Jing Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Loss of cargo binding in the human myosin VI deafness mutant (R1166X) leads to increased actin filament binding

(2016) S. D. Arden et al.   BIOCHEMICAL JOURNAL

Calcium-regulated import of myosin IC into the nucleus

(2016) Ivan V. Maly et al.   Cytoskeleton

Actin, actin-binding proteins, and actin-related proteins in the nucleus

(2016) Ildikó Kristó et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain

(2016) Hans-Peter Wollscheid et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin

(2016) Ballachanda N Devaiah et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chromosome territory relocation during DNA repair requires nuclear myosin 1 recruitment to chromatin mediated by ϒ-H2AX signaling

(2016) Mugdha Kulashreshtha et al.   NUCLEIC ACIDS RESEARCH

Calmodulin in complex with the first IQ motif of myosin-5a functions as an intact calcium sensor

(2016) Mei Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Cargo Recognition by Unconventional Myosins in Cellular Trafficking

(2016) Jianchao Li et al.   TRAFFIC

How Myosin Generates Force on Actin Filaments

(2016) Anne Houdusse et al.   TRENDS IN BIOCHEMICAL SCIENCES

A Role for Nuclear F-Actin Induction in Human Cytomegalovirus Nuclear Egress

(2016) Adrian R. Wilkie et al.   mBio

Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain

(2016) Hans-Peter Wollscheid et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin

(2016) Ballachanda N Devaiah et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Myosins as fundamental components during tumorigenesis: diverse and indispensable

(2016) Yan-Ruide Li et al.   Oncotarget

Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation

(2015) Bader Almuzzaini et al.   BMC BIOLOGY

Nuclear actin and myosins in adenovirus infection

(2015) Beata Fuchsova et al.   EXPERIMENTAL CELL RESEARCH

Myosin VI regulates gene pairing and transcriptional pause release in T cells

(2015) Cornelia E. Zorca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-1/2 that promotes efficient DNA repair

(2015) Brittany J Belin et al.   eLife

Myosin-Va and Dynamic Actin Oppose Microtubules to Drive Long-Range Organelle Transport

(2014) Richard D. Evans et al.   CURRENT BIOLOGY

The F-act's of nuclear actin

(2014) Michael J Hendzel   CURRENT OPINION IN CELL BIOLOGY

Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis

(2014) Jessica L. Ouderkirk et al.   Cytoskeleton

Nuclear actin filaments recruit cofilin and actin-related protein 3, and their formation is connected with a mitotic block

(2014) Alžběta Kalendová et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Structure of myosin-1c tail bound to calmodulin provides insights into calcium-mediated conformational coupling

(2014) Qing Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Myosin 16 levels fluctuate during the cell cycle and are downregulated in response to DNA replication stress

(2013) Richard S. Cameron et al.   Cytoskeleton

Identification of signals that facilitate isoform specific nucleolar localization of myosin IC

(2013) Ryan S. Schwab et al.   EXPERIMENTAL CELL RESEARCH

To be or not to be assembled: progressing into nuclear actin filaments

(2013) Robert Grosse et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mouse Nuclear Myosin I Knock-Out Shows Interchangeability and Redundancy of Myosin Isoforms in the Cell Nucleus

(2013) Tomáš Venit et al.   PLoS One

Nucleotide Excision Repair in Eukaryotes

(2013) O. D. Scharer   Cold Spring Harbor Perspectives in Biology

A myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells

(2013) T C Izidoro-Toledo et al.   Cell Death & Disease

Nuclear Myosin 1c Facilitates the Chromatin Modifications Required to Activate rRNA Gene Transcription and Cell Cycle Progression

(2013) Aishe Sarshad et al.   PLoS Genetics

Chromosome territories reposition during DNA damage-repair response

(2013) Ishita S Mehta et al.   GENOME BIOLOGY

Identification and characterization of a novel myosin Ic isoform that localizes to the nucleus

(2012) Ivanna Ihnatovych et al.   Cytoskeleton

Kinetic properties and small-molecule inhibition of human myosin-6

(2012) Sarah M. Heissler et al.   FEBS LETTERS

Nuclear actin and myosins at a glance

(2012) P. de Lanerolle   JOURNAL OF CELL SCIENCE

The myosin superfamily at a glance

(2012) M. A. Hartman et al.   JOURNAL OF CELL SCIENCE

Specific Nuclear Localizing Sequence Directs Two Myosin Isoforms to the Cell Nucleus in Calmodulin-Sensitive Manner

(2012) Rastislav Dzijak et al.   PLoS One

Myosin IC generates power over a range of loads via a new tension-sensing mechanism

(2012) M. J. Greenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Principles of Unconventional Myosin Function and Targeting

(2011) M. Amanda Hartman et al.   Annual Review of Cell and Developmental Biology

Chromatin remodelling in mammalian cells by ISWI-type complexes - where, when and why?

(2011) Fabian Erdel et al.   FEBS Journal

Nuclear actin and myosins: Life without filaments

(2011) Primal de Lanerolle et al.   NATURE CELL BIOLOGY

The Chromatin Remodelling Complex B-WICH Changes the Chromatin Structure and Recruits Histone Acetyl-Transferases to Active rRNA Genes

(2011) Anna Vintermist et al.   PLoS One

Kinetic Analysis Reveals Differences in the Binding Mechanism of Calmodulin and Calmodulin-like Protein to the IQ Motifs of Myosin-10

(2010) Ariel J. Caride et al.   BIOCHEMISTRY

Transcription-dependent rearrangements of actin and nuclear myosin I in the nucleolus

(2010) V. V. Philimonenko et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Myosin VI Is Differentially Regulated by DNA Damage in p53- and Cell Type-dependent Manners

(2010) Seong Jun Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Robust Mechanosensing and Tension Generation by Myosin VI

(2010) Peiying Chuan et al.   JOURNAL OF MOLECULAR BIOLOGY

DNA Damage Response

(2010) G. Giglia-Mari et al.   Cold Spring Harbor Perspectives in Biology

Chromosome Territories

(2010) T. Cremer et al.   Cold Spring Harbor Perspectives in Biology

Activation of Estrogen-Responsive Genes Does Not Require Their Nuclear Co-Localization

(2010) Silvia Kocanova et al.   PLoS Genetics

Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts

(2010) Ishita S Mehta et al.   GENOME BIOLOGY

Nuclear Myosin II Regulates the Assembly of Preinitiation Complex for ICAM-1 Gene Transcription

(2009) Qingjie Li et al.   GASTROENTEROLOGY

Myosin VI is a modulator of androgen-dependent gene expression

(2009) Vaarala   ONCOLOGY REPORTS

Unconventional myosin traffic in cells reveals a selective actin cytoskeleton

(2009) C. M. Brawley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of cell membrane tension by myosin-I

(2009) R. Nambiar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myosin-10 and actin filaments are essential for mitotic spindle function

(2008) Sarah Woolner et al.   JOURNAL OF CELL BIOLOGY

Calcium sensitivity of the cross-bridge cycle of Myo1c, the adaptation motor in the inner ear

(2008) N. Adamek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules

(2008) Q. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA