Intersection of TKS5 and FGD1/CDC42 signaling cascades directs the formation of invadopodia

Cellular self-organization: generating order from the abyss

(2020) Derek McCusker   MOLECULAR BIOLOGY OF THE CELL

A proximity-labeling proteomic approach to investigate invadopodia molecular landscape in breast cancer cells

(2020) Sylvie Thuault et al.   Scientific Reports

Direct measurement of vertical forces shows correlation between mechanical activity and proteolytic ability of invadopodia

(2020) E. Dalaka et al.   Science Advances

MT1-MMP directs force-producing proteolytic contacts that drive tumor cell invasion

(2019) Robin Ferrari et al.   Nature Communications

Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

(2019) Halil Bagci et al.   NATURE CELL BIOLOGY

EGF Regulates the Interaction of Tks4 with Src through Its SH2 and SH3 Domains

(2018) Metta Dülk et al.   BIOCHEMISTRY

Tks adaptor proteins at a glance

(2018) Priyanka Saini et al.   JOURNAL OF CELL SCIENCE

LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration

(2018) Elvira Infante et al.   Nature Communications

Divergent Matrix-Remodeling Strategies Distinguish Developmental from Neoplastic Mammary Epithelial Cell Invasion Programs

(2018) Tamar Y. Feinberg et al.   DEVELOPMENTAL CELL

FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis

(2018) Laura Chan Wah Hak et al.   NATURE CELL BIOLOGY

Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function

(2018) Alessia Castagnino et al.   ONCOGENE

Nucleus–Invadopodia Duo During Cancer Invasion

(2018) Robin Ferrari et al.   TRENDS IN CELL BIOLOGY

Tumor Cell Invadopodia: Invasive Protrusions that Orchestrate Metastasis

(2017) Robert J. Eddy et al.   TRENDS IN CELL BIOLOGY

Cellular and Molecular Mechanisms of MT1-MMP-Dependent Cancer Cell Invasion

(2016) Antonio Castro-Castro et al.   Annual Review of Cell and Developmental Biology

Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases

(2016) Suyong Choi et al.   NATURE CELL BIOLOGY

Frequency and amplitude control of cortical oscillations by phosphoinositide waves

(2016) Ding Xiong et al.   Nature Chemical Biology

Minireview: Role of genetic changes of faciogenital dysplasia protein 1 in human disease

(2016) Nancy G. Pedigo et al.   PHYSIOLOGICAL GENOMICS

The role of Tks adaptor proteins in invadopodia formation, growth and metastasis of melanoma

(2016) Shinji Iizuka et al.   Oncotarget

Spontaneous cell polarization: Feedback control of Cdc42 GTPase breaks cellular symmetry

(2015) Sophie G. Martin   BIOESSAYS

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

(2015) Marco Y. Hein et al.   CELL

Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network

(2015) Vira V. Artym et al.   JOURNAL OF CELL BIOLOGY

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer

(2015) C Lodillinsky et al.   ONCOGENE

The Invadopodia Scaffold Protein Tks5 Is Required for the Growth of Human Breast Cancer Cells In Vitro and In Vivo

(2015) Barbara Blouw et al.   PLoS One

Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42–Tuba pathway

(2014) Amélie Juin et al.   JOURNAL OF CELL BIOLOGY

Cdc42 and Tks5

(2014) Julie Di Martino et al.   Cell Adhesion & Migration

Invadopodia Are Required for Cancer Cell Extravasation and Are a Therapeutic Target for Metastasis

(2014) Hon S. Leong et al.   Cell Reports

Multiparametric Classification Links Tumor Microenvironments with Tumor Cell Phenotype

(2014) Bojana Gligorijevic et al.   PLOS BIOLOGY

Tks5 and SHIP2 Regulate Invadopodium Maturation, but Not Initiation, in Breast Carcinoma Cells

(2013) Ved P. Sharma et al.   CURRENT BIOLOGY

Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma

(2013) C. M.-C. Li et al.   GENES & DEVELOPMENT

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

(2013) Pedro Monteiro et al.   JOURNAL OF CELL BIOLOGY

Protein Interaction Network of the Mammalian Hippo Pathway Reveals Mechanisms of Kinase-Phosphatase Interactions

(2013) A. L. Couzens et al.   Science Signaling

N-WASP coordinates the delivery and F-actin–mediated capture of MT1-MMP at invasive pseudopods

(2012) Xinzi Yu et al.   JOURNAL OF CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Transducer of Cdc42-dependent actin assembly promotes breast cancer invasion and metastasis

(2012) H Chander et al.   ONCOGENE

Network Analysis of the Focal Adhesion to Invadopodia Transition Identifies a PI3K-PKC  Invasive Signaling Axis

(2012) D. Hoshino et al.   Science Signaling

Synergistic BAR–NPF interactions in actin-driven membrane remodeling

(2012) Shiro Suetsugu et al.   TRENDS IN CELL BIOLOGY

Adhesion rings surround invadopodia and promote maturation

(2012) K. M. Branch et al.   Biology Open

Degrading Devices: Invadosomes in Proteolytic Cell Invasion

(2011) Stefan Linder et al.   Annual Review of Cell and Developmental Biology

Sensing and Modulation of Invadopodia across a Wide Range of Rigidities

(2011) Aron Parekh et al.   BIOPHYSICAL JOURNAL

Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis

(2011) Mark A. Eckert et al.   CANCER CELL

An EGFR-Src-Arg-Cortactin Pathway Mediates Functional Maturation of Invadopodia and Breast Cancer Cell Invasion

(2011) C. C. Mader et al.   CANCER RESEARCH

Cancer Cell-Associated MT1-MMP Promotes Blood Vessel Invasion and Distant Metastasis in Triple-Negative Mammary Tumors

(2011) J. Y. Perentes et al.   CANCER RESEARCH

Requirement for FBP17 in Invadopodia Formation by Invasive Bladder Tumor Cells

(2011) Hayato Yamamoto et al.   JOURNAL OF UROLOGY

The Aarskog-Scott Syndrome Protein Fgd1 Regulates Podosome Formation and Extracellular Matrix Remodeling in Transforming Growth Factor  -Stimulated Aortic Endothelial Cells

(2011) T. Daubon et al.   MOLECULAR AND CELLULAR BIOLOGY

Physiological type I collagen organization induces the formation of a novel class of linear invadosomes

(2011) Amélie Juin et al.   MOLECULAR BIOLOGY OF THE CELL

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

(2011) Danielle A. Murphy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Homolog of the Five SH3-Domain Protein (HOFI/SH3PXD2B) Regulates Lamellipodia Formation and Cell Spreading

(2011) Árpád Lányi et al.   PLoS One

MassChroQ: A versatile tool for mass spectrometry quantification

(2011) Benoît Valot et al.   PROTEOMICS

Cdc42-Interacting Protein 4 Promotes Breast Cancer Cell Invasion and Formation of Invadopodia through Activation of N-WASp

(2010) C. S. Pichot et al.   CANCER RESEARCH

MT1-MMP Is Required for Myeloid Cell Fusion via Regulation of Rac1 Signaling

(2010) Pilar Gonzalo et al.   DEVELOPMENTAL CELL

Cancer Dissemination—Lessons from Leukocytes

(2010) Chris D. Madsen et al.   DEVELOPMENTAL CELL

Faciogenital Dysplasia Protein Fgd1 Regulates Invadopodia Biogenesis and Extracellular Matrix Degradation and Is Up-regulated in Prostate and Breast Cancer

(2009) I. Ayala et al.   CANCER RESEARCH

Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation

(2009) Matthew Oser et al.   JOURNAL OF CELL BIOLOGY

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

(2009) Farideh Sabeh et al.   JOURNAL OF CELL BIOLOGY

Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation

(2009) S. S. Stylli et al.   JOURNAL OF CELL SCIENCE

The Novel Adaptor Protein Tks4 (SH3PXD2B) Is Required for Functional Podosome Formation

(2009) Matthew D. Buschman et al.   MOLECULAR BIOLOGY OF THE CELL

N-WASP and cortactin are involved in invadopodium-dependent chemotaxis to EGF in breast tumor cells

(2009) Vera DesMarais et al.   CELL MOTILITY AND THE CYTOSKELETON

Characterisation of breast cancer cell lines and establishment of a novel isogenic subclone to study migration, invasion and tumourigenicity

(2008) Linda Hughes et al.   CLINICAL & EXPERIMENTAL METASTASIS

Sequential signals toward podosome formation in NIH-src cells

(2008) Tsukasa Oikawa et al.   JOURNAL OF CELL BIOLOGY

The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA

(2008) Mika Sakurai-Yageta et al.   JOURNAL OF CELL BIOLOGY

Breaching the basement membrane: who, when and how?

(2008) R. Grant Rowe et al.   TRENDS IN CELL BIOLOGY