Reversible control of biomaterial properties for dynamically tuning cell behavior

Programming Stimuli-Responsive Behavior into Biomaterials

(2019) Barry A. Badeau et al.   Annual Review of Biomedical Engineering

Bioactive site-specifically modified proteins for 4D patterning of gel biomaterials

(2019) Jared A. Shadish et al.   NATURE MATERIALS

Redox Biology in Neurological Function, Dysfunction, and Aging

(2018) Rodrigo Franco et al.   ANTIOXIDANTS & REDOX SIGNALING

Reversible Control of Network Properties in Azobenzene-Containing Hyaluronic Acid-Based Hydrogels

(2018) Adrianne M. Rosales et al.   BIOCONJUGATE CHEMISTRY

Reversibly tuning hydrogel stiffness through photocontrolled dynamic covalent crosslinks

(2018) Joseph V. Accardo et al.   Chemical Science

A Reversible and Repeatable Thiol–Ene Bioconjugation for Dynamic Patterning of Signaling Proteins in Hydrogels

(2018) Joseph C. Grim et al.   ACS Central Science

Reversible Chemo-Topographic Control of Adhesion in Polydopamine Nanomembranes

(2018) Po-Ju Chiang et al.   MACROMOLECULAR MATERIALS AND ENGINEERING

In Situ Imprinting of Topographic Landscapes at the Cell–Substrate Interface

(2018) Derek S. Hernandez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reversible self-assembly of superstructured networks

(2018) Ronit Freeman et al.   SCIENCE

Spatially and temporally controlled hydrogels for tissue engineering

(2017) Jeroen Leijten et al.   MATERIALS SCIENCE & ENGINEERING R-REPORTS

Mechanical forces direct stem cell behaviour in development and regeneration

(2017) Kyle H. Vining et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dynamically tunable cell culture platforms for tissue engineering and mechanobiology

(2017) Koichiro Uto et al.   PROGRESS IN POLYMER SCIENCE

Instructing cells with programmable peptide DNA hybrids

(2017) Ronit Freeman et al.   Nature Communications

Spatio-Temporal Control of Dynamic Topographic Patterns on Azopolymers for Cell Culture Applications

(2016) Carmela Rianna et al.   ADVANCED FUNCTIONAL MATERIALS

Intracellular Ca 2+ signaling and Ca 2+ microdomains in the control of cell survival, apoptosis and autophagy

(2016) Rita M.L. La Rovere et al.   CELL CALCIUM

Matrix stiffening promotes a tumor vasculature phenotype

(2016) Francois Bordeleau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temporal Modulation of Stem Cell Activity Using Magnetoactive Hydrogels

(2016) Amr A. Abdeen et al.   Advanced Healthcare Materials

Stiffening hydrogels for investigating the dynamics of hepatic stellate cell mechanotransduction during myofibroblast activation

(2016) Steven R. Caliari et al.   Scientific Reports

Reversible Holographic Patterns on Azopolymers for Guiding Cell Adhesion and Orientation

(2015) Carmela Rianna et al.   ACS Applied Materials & Interfaces

Photoresponsive Elastic Properties of Azobenzene-Containing Poly(ethylene-glycol)-Based Hydrogels

(2015) Adrianne M. Rosales et al.   BIOMACROMOLECULES

Lithography-free fabrication of reconfigurable substrate topography for contact guidance

(2015) Pitirat Pholpabu et al.   BIOMATERIALS

Dynamic stiffening of poly(ethylene glycol)-based hydrogels to direct valvular interstitial cell phenotype in a three-dimensional environment

(2015) Kelly M. Mabry et al.   BIOMATERIALS

A photoreversible protein-patterning approach for guiding stem cell fate in three-dimensional gels

(2015) Cole A. DeForest et al.   NATURE MATERIALS

Dynamic phototuning of 3D hydrogel stiffness

(2015) Ryan S. Stowers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rationally Designed Dynamic Protein Hydrogels with Reversibly Tunable Mechanical Properties

(2014) Na Kong et al.   ADVANCED FUNCTIONAL MATERIALS

Photo-Click Living Strategy for Controlled, Reversible Exchange of Biochemical Ligands

(2014) Navakanth R. Gandavarapu et al.   ADVANCED MATERIALS

Materials as stem cell regulators

(2014) William L. Murphy et al.   NATURE MATERIALS

Hydrogel scaffolds as in vitro models to study fibroblast activation in wound healing and disease

(2014) Megan E. Smithmyer et al.   Biomaterials Science

Dynamic Display of Bioactivity through Host-Guest Chemistry

(2013) Job Boekhoven et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic and reversible surface topography influences cell morphology

(2013) Jennifer D. Kiang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

The Wound Healing Process: An Overview of the Cellular and Molecular Mechanisms

(2013) T Velnar et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

In situ cell manipulation through enzymatic hydrogel photopatterning

(2013) Katarzyna A. Mosiewicz et al.   NATURE MATERIALS

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Designing Cell-Compatible Hydrogels for Biomedical Applications

(2012) D. Seliktar   SCIENCE

Non-covalent interactions

(2012) Ibon Alkorta et al.   Computational and Theoretical Chemistry

Stem Cell Response to Spatially and Temporally Displayed and Reversible Surface Topography

(2012) Murat Guvendiren et al.   Advanced Healthcare Materials

Dynamic Topographical Control of Mesenchymal Stem Cells by Culture on Responsive Poly(ϵ-caprolactone) Surfaces

(2011) Duy M. Le et al.   ADVANCED MATERIALS

Photoreversible Patterning of Biomolecules within Click-Based Hydrogels

(2011) Cole A. DeForest et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering spatial control of multiple differentiation fates within a stem cell population

(2011) Elmer D.F. Ker et al.   BIOMATERIALS

Biomedical applications of biodegradable polymers

(2011) Bret D. Ulery et al.   JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS

Redox-Switchable Surface for Controlling Peptide Structure

(2011) Brian M. Lamb et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative Evaluation of Mechanosensing of Cells on Dynamically Tunable Hydrogels

(2011) Hiroshi Y. Yoshikawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoscale tissue engineering: spatial control over cell-materials interactions

(2011) Ian Wheeldon et al.   NANOTECHNOLOGY

Cytocompatible click-based hydrogels with dynamically tunable properties through orthogonal photoconjugation and photocleavage reactions

(2011) Cole A. DeForest et al.   Nature Chemistry

Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2

(2010) J. Patterson et al.   BIOMATERIALS

Hyaluronic acid hydrogels with controlled degradation properties for oriented bone regeneration

(2010) Jennifer Patterson et al.   BIOMATERIALS

Spatiotemporal controlled delivery of nanoparticles to injured vasculature

(2010) J. M. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanotopographical Control of Stem Cell Differentiation

(2010) Laura E. McNamara et al.   Journal of Tissue Engineering

Dynamic Hydrogels: Switching of 3D Microenvironments Using Two-Component Naturally Derived Extracellular Matrices

(2009) Brian M. Gillette et al.   ADVANCED MATERIALS

Using Azobenzene-Embedded Self-Assembled Monolayers To Photochemically Control Cell Adhesion Reversibly

(2009) Dingbin Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering Substrate Topography at the Micro- and Nanoscale to Control Cell Function

(2009) Christopher J. Bettinger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stimuli-responsive interfaces and systems for the control of protein–surface and cell–surface interactions

(2009) Martin A. Cole et al.   BIOMATERIALS

The relationship between fibroblast growth and the dynamic stiffnesses of a DNA crosslinked hydrogel

(2009) Frank X. Jiang et al.   BIOMATERIALS

The extracellular matrix in development and morphogenesis: A dynamic view

(2009) Tania Rozario et al.   DEVELOPMENTAL BIOLOGY

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

(2009) April M. Kloxin et al.   SCIENCE

Protein-Based Hydrogels with Tunable Dynamic Responses

(2008) Zhijie Sui et al.   ADVANCED FUNCTIONAL MATERIALS

Directing osteogenic and myogenic differentiation of MSCs: interplay of stiffness and adhesive ligand presentation

(2008) Andrew S. Rowlands et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanotransduction in development: a growing role for contractility

(2008) Michele A. Wozniak et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Conformational changes of calmodulin upon Ca2+ binding studied with a microfluidic mixer

(2008) H. Y. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlled drug delivery in tissue engineering

(2007) Marco Biondi et al.   ADVANCED DRUG DELIVERY REVIEWS