Inclusion Formation and Toxicity of the ALS Protein RGNEF and Its Association with the Microtubule Network

A Systematic and Comprehensive Review on Disease-Causing Genes in Amyotrophic Lateral Sclerosis

(2020) E. Srinivasan et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Rgnef promotes ovarian tumor progression and confers protection from oxidative stress

(2019) Elizabeth G. Kleinschmidt et al.   ONCOGENE

Axonal transport and neurological disease

(2019) James N. Sleigh et al.   Nature Reviews Neurology

TDP-43 aggregation inside micronuclei reveals a potential mechanism for protein inclusion formation in ALS

(2019) Cristian A. Droppelmann et al.   Scientific Reports

A matter of balance

(2018) Aaron D Gitler et al.   eLife

A novel overlapping NLS/NES region within the PH domain of Rho Guanine Nucleotide Exchange Factor (RGNEF) regulates its nuclear-cytoplasmic localization

(2018) Michael V. Tavolieri et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

ALS Yeast Models—Past Success Stories and New Opportunities

(2018) Sonja E. Di Gregorio et al.   Frontiers in Molecular Neuroscience

Rho guanine nucleotide exchange factor (RGNEF) is a prosurvival factor under stress conditions

(2017) Kevin Cheung et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Amyotrophic lateral sclerosis

(2017) Orla Hardiman et al.   Nature Reviews Disease Primers

Protein folding alterations in amyotrophic lateral sclerosis

(2016) Sonam Parakh et al.   BRAIN RESEARCH

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Gastrin-stimulated Gα13Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells

(2015) Miriam Masià-Balagué et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuropathology of Amyotrophic Lateral Sclerosis and Its Variants

(2015) Shahram Saberi et al.   NEUROLOGIC CLINICS

Colchicine—Update on mechanisms of action and therapeutic uses

(2015) Ying Ying Leung et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Carbon source dependent promoters in yeasts

(2014) Katrin Weinhandl et al.   Microbial Cell Factories

Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS

(2014) Bradley N. Smith et al.   NEURON

The emerging role of guanine nucleotide exchange factors in ALS and other neurodegenerative diseases

(2014) Cristian A. Droppelmann et al.   Frontiers in Cellular Neuroscience

ARHGEF28 gene exon 6/intron 6 junction mutations in Chinese amyotrophic lateral sclerosis cohort

(2014) Yan Ma et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Harnessing the power of yeast to unravel the molecular basis of neurodegeneration

(2013) Sandra Tenreiro et al.   JOURNAL OF NEUROCHEMISTRY

Genetics of amyotrophic lateral sclerosis: an update

(2013) Sheng Chen et al.   Molecular Neurodegeneration

Detection of a novel frameshift mutation and regions with homozygosis within ARHGEF28 gene in familial amyotrophic lateral sclerosis

(2013) Cristian A. Droppelmann et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Co-aggregation of RNA binding proteins in ALS spinal motor neurons: evidence of a common pathogenic mechanism

(2012) Brian A. Keller et al.   ACTA NEUROPATHOLOGICA

Rho guanine nucleotide exchange factor is an NFL mRNA destabilizing factor that forms cytoplasmic inclusions in amyotrophic lateral sclerosis

(2012) Cristian A. Droppelmann et al.   NEUROBIOLOGY OF AGING

Rgnef (p190RhoGEF) Knockout Inhibits RhoA Activity, Focal Adhesion Establishment, and Cell Motility Downstream of Integrins

(2012) Nichol L. G. Miller et al.   PLoS One

Modeling ALS and FTLD proteinopathies in yeast: An efficient approach for studying protein aggregation and toxicity

(2012) Dmitry Kryndushkin et al.   Prion

p190RhoGEF (Rgnef) Promotes Colon Carcinoma Tumor Progression via Interaction with Focal Adhesion Kinase

(2011) Hong-Gang Yu et al.   CANCER RESEARCH

RNA-binding proteins with prion-like domains in ALS and FTLD-U

(2011) Aaron D. Gitler et al.   Prion

The Role of Environmental Exposures in Neurodegeneration and Neurodegenerative Diseases

(2011) Jason R. Cannon et al.   TOXICOLOGICAL SCIENCES

Human low molecular weight neurofilament (NFL) mRNA interacts with a predicted p190RhoGEF homologue (RGNEF) in humans

(2010) Kathryn Volkening et al.   Amyotrophic Lateral Sclerosis

Simple is good: yeast models of neurodegeneration

(2010) Sandra Tenreiro et al.   FEMS YEAST RESEARCH

Neurodegenerative diseases: Lessons from genome-wide screens in small model organisms

(2009) Tjakko J. van Ham et al.   EMBO Molecular Medicine

Protein Misfolding and Neurodegeneration

(2008) Claudio Soto et al.   ARCHIVES OF NEUROLOGY

Split-Ubiquitin and the Split-Protein Sensors: Chessman for the Endgame

(2008) Judith Müller et al.   CHEMBIOCHEM