Rgnef (p190RhoGEF) Knockout Inhibits RhoA Activity, Focal Adhesion Establishment, and Cell Motility Downstream of Integrins

p190RhoGEF (Rgnef) Promotes Colon Carcinoma Tumor Progression via Interaction with Focal Adhesion Kinase

(2011) Hong-Gang Yu et al.   CANCER RESEARCH

A Novel Spatiotemporal RhoC Activation Pathway Locally Regulates Cofilin Activity at Invadopodia

(2011) Jose Javier Bravo-Cordero et al.   CURRENT BIOLOGY

Targeting of the RhoGEF Ect2 to the Equatorial Membrane Controls Cleavage Furrow Formation during Cytokinesis

(2011) Kuan-Chung Su et al.   DEVELOPMENTAL CELL

RhoA GTPase Is Dispensable for Actomyosin Regulation but Is Essential for Mitosis in Primary Mouse Embryonic Fibroblasts

(2011) Jaime Melendez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RhoA and RhoC have distinct roles in migration and invasion by acting through different targets

(2011) Francisco M. Vega et al.   JOURNAL OF CELL BIOLOGY

RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

(2011) Ben Jackson et al.   MOLECULAR BIOLOGY OF THE CELL

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

(2011) Christophe Guilluy et al.   NATURE CELL BIOLOGY

Molecular Architecture and Function of Matrix Adhesions

(2011) B. Geiger et al.   Cold Spring Harbor Perspectives in Biology

Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration

(2010) Margaret L. Gardel et al.   Annual Review of Cell and Developmental Biology

Knock-in Mutation Reveals an Essential Role for Focal Adhesion Kinase Activity in Blood Vessel Morphogenesis and Cell Motility-Polarity but Not Cell Proliferation

(2010) Ssang-Taek Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Rho Guanine Nucleotide Exchange Factor AKAP13 (BRX) Is Essential for Cardiac Development in Mice

(2010) Chantal M. Mayers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility

(2009) Alok Tomar et al.   CURRENT OPINION IN CELL BIOLOGY

A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells

(2009) A. Tomar et al.   JOURNAL OF CELL SCIENCE

Guanine Nucleotide Exchange Factor-H1 Regulates Cell Migration via Localized Activation of RhoA at the Leading Edge

(2009) Perihan Nalbant et al.   MOLECULAR BIOLOGY OF THE CELL

PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

(2008) Yangmi Lim et al.   JOURNAL OF CELL BIOLOGY

Membrane recognition by phospholipid-binding domains

(2008) Mark A. Lemmon   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY