Tobacco, but Not Nicotine and Flavor-Less Electronic Cigarettes, Induces ACE2 and Immune Dysregulation

Hypomethylation of LINE-1 repeat elements and global loss of DNA hydroxymethylation in vapers and smokers

(2020) Andrew W. Caliri et al.   Epigenetics

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China

(2020) Zunyou Wu et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2

(2020) Guoshuai Cai et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients

(2020) Zhuo Zhou et al.   Cell Host & Microbe

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

(2020) Shuai Xia et al.   CELL RESEARCH

SARS ‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells

(2020) Soeren Lukassen et al.   EMBO JOURNAL

Active smoking is not associated with severity of coronavirus disease 2019 (COVID-19)

(2020) Giuseppe Lippi et al.   European Journal of Internal Medicine

COVID-19 and vaping: risk for increased susceptibility to SARS-CoV-2 infection?

(2020) Kielan Darcy McAlinden et al.   EUROPEAN RESPIRATORY JOURNAL

ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19

(2020) Janice M. Leung et al.   EUROPEAN RESPIRATORY JOURNAL

Smoking-Mediated Upregulation of the Androgen Pathway Leads to Increased SARS-CoV-2 Susceptibility

(2020) Jaideep Chakladar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The impact of COPD and smoking history on the severity of COVID‐19: A systemic review and meta‐analysis

(2020) Qianwen Zhao et al.   JOURNAL OF MEDICAL VIROLOGY

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells

(2020) Shutoku Matsuyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

COVID-19 and smoking: A systematic review of the evidence

(2020) Constantine Vardavas et al.   Tobacco Induced Diseases

Tobacco smoking and COVID-19 infection

(2020) Richard N van Zyl-Smit et al.   Lancet Respiratory Medicine

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

(2020) Nina Le Bert et al.   NATURE

Electronic vs Combustible Cigarette Effects on Inflammasome Component Release into Human Lung

(2019) MuChun Tsai et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Fourth generation e-cigarette vaping induces transient lung inflammation and gas exchanges disturbances: results from two randomized clinical trials

(2019) Martin Chaumont et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Gene Expression Alterations in the Bronchial Epithelium of e-Cigarette Users

(2019) Sean E. Corbett et al.   CHEST

Effects of Electronic Cigarette Constituents on the Human Lung: A Pilot Clinical Trial

(2019) Min-Ae Song et al.   Cancer Prevention Research

Human Endogenous Retroviruses and Type 1 Diabetes

(2019) Sandrine Levet et al.   Current Diabetes Reports

E-cigarette flavored pods induce inflammation, epithelial barrier dysfunction, and DNA damage in lung epithelial cells and monocytes

(2019) Thivanka Muthumalage et al.   Scientific Reports

E-Cigarette Use Causes a Unique Innate Immune Response in the Lung, Involving Increased Neutrophilic Activation and Altered Mucin Secretion

(2018) Boris Reidel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The effects of electronic cigarette vapour on the lung: direct comparison to tobacco smoke

(2018) Viktorija Reinikovaite et al.   EUROPEAN RESPIRATORY JOURNAL

Changes in Electronic Cigarette Use Among Adults in the United States, 2014-2016

(2018) Wei Bao et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Pro-inflammatory effects of e-cigarette vapour condensate on human alveolar macrophages

(2018) Aaron Scott et al.   THORAX

Regulation of NLRP3 Inflammasome by Phosphorylation

(2018) Nan Song et al.   Frontiers in Immunology

Notes from the Field: Use of Electronic Cigarettes and Any Tobacco Product Among Middle and High School Students — United States, 2011–2018

(2018) Karen A. Cullen et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

CXCL1 and CXCL2 Regulate NLRP3 Inflammasome Activation via G-Protein–Coupled Receptor CXCR2

(2017) Monoranjan Boro et al.   JOURNAL OF IMMUNOLOGY

p38δ MAPKHighlights

(2016) Kristiina Rajamäki et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines

(2016) Vicky Yu et al.   ORAL ONCOLOGY

Will chronic e-cigarette use cause lung disease?

(2015) Temperance R. Rowell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Are E-cigarettes a safe and good alternative to cigarette smoking?

(2015) Oren Rom et al.   Annals of the New York Academy of Sciences

Vapors Produced by Electronic Cigarettes and E-Juices with Flavorings Induce Toxicity, Oxidative Stress, and Inflammatory Response in Lung Epithelial Cells and in Mouse Lung

(2015) Chad A. Lerner et al.   PLoS One

Structural mechanisms of inflammasome assembly

(2014) Alvin Lu et al.   FEBS Journal

A systematic review of health effects of electronic cigarettes

(2014) Charlotta Pisinger et al.   PREVENTIVE MEDICINE

Altered T-bet Dominance in IFN- -Decoupled CD4+ T Cells with Attenuated Cytokine Storm and Preserved Memory in Influenza

(2013) A. Dutta et al.   JOURNAL OF IMMUNOLOGY

Breath biomarkers in diagnosis of pulmonary diseases

(2012) Meigui Zhou et al.   CLINICA CHIMICA ACTA

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Cigarette Smoking and Inflammation

(2011) J. Lee et al.   JOURNAL OF DENTAL RESEARCH

Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response

(2011) I. Glowacka et al.   JOURNAL OF VIROLOGY

Rapid Regulatory T-Cell Response Prevents Cytokine Storm in CD28 Superagonist Treated Mice

(2009) Tea Gogishvili et al.   PLoS One

Smoking and Chronic Obstructive Pulmonary Disease (COPD). Parallel Epidemics of the 21st Century

(2009) Rafael Laniado-Laborín   International Journal of Environmental Research and Public Health

A NOD2-NALP1 complex mediates caspase-1-dependent IL-1  secretion in response to Bacillus anthracis infection and muramyl dipeptide

(2008) L.-C. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tobacco use increases susceptibility to bacterial infection

(2008) Juhi Bagaitkar et al.   Tobacco Induced Diseases