CXCL1 and CXCL2 Regulate NLRP3 Inflammasome Activation via G-Protein–Coupled Receptor CXCR2

Carrageenan-induced inflammation promotes ROS generation and neutrophil extracellular trap formation in a mouse model of peritonitis

(2016) Cristiane R. Barth et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

(2016) Yuan He et al.   NATURE

Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses

(2016) Monoranjan Boro et al.   Scientific Reports

The CCL2 chemokine is a negative regulator of autophagy and necrosis in luminal B breast cancer cells

(2015) Wei Bin Fang et al.   BREAST CANCER RESEARCH AND TREATMENT

Nicorandil inhibits neutrophil recruitment in carrageenan-induced experimental pleurisy in mice

(2015) Tamires C. Matsui et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

β-arrestin1 Is Critical for the Full Activation of NLRP3 and NLRC4 Inflammasomes

(2015) Kairui Mao et al.   JOURNAL OF IMMUNOLOGY

CXCR2 is essential for cerebral endothelial activation and leukocyte recruitment during neuroinflammation

(2015) Fengjiao Wu et al.   Journal of Neuroinflammation

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Integrin-linked Kinase Modulates Lipopolysaccharide- andHelicobacter pylori-induced Nuclear Factor κB-activated Tumor Necrosis Factor-α Production via Regulation of p65 Serine 536 Phosphorylation

(2014) Afsar U. Ahmed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCL1 Contributes to Host Defense in Polymicrobial Sepsis via Modulating T Cell and Neutrophil Functions

(2014) Liliang Jin et al.   JOURNAL OF IMMUNOLOGY

CCL2 Shapes Macrophage Polarization by GM-CSF and M-CSF: Identification of CCL2/CCR2-Dependent Gene Expression Profile

(2014) E. Sierra-Filardi et al.   JOURNAL OF IMMUNOLOGY

Activated PAR-2 Regulates Pancreatic Cancer Progression through ILK/HIF-α–Induced TGF-α Expression and MEK/VEGF-A–Mediated Angiogenesis

(2013) Li-Hsun Chang et al.   AMERICAN JOURNAL OF PATHOLOGY

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation

(2013) K. De Filippo et al.   BLOOD

The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation

(2013) Naeha Subramanian et al.   CELL

Mechanisms of NOD-like Receptor-Associated Inflammasome Activation

(2013) Haitao Wen et al.   IMMUNITY

Mitochondrial Reactive Oxygen Species Induces NLRP3-Dependent Lysosomal Damage and Inflammasome Activation

(2013) M. E. Heid et al.   JOURNAL OF IMMUNOLOGY

Mycobacteria-Infected Dendritic Cells Attract Neutrophils That Produce IL-10 and Specifically Shut Down Th17 CD4 T Cells through Their IL-10 Receptor

(2013) E. Doz et al.   JOURNAL OF IMMUNOLOGY

Role of Interleukin-32 in Helicobacter pylori-Induced Gastric Inflammation

(2012) Kosuke Sakitani et al.   INFECTION AND IMMUNITY

Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation

(2012) Christine Juliana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of NLRC4 is critical for inflammasome activation

(2012) Yan Qu et al.   NATURE

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

(2012) Geun-Shik Lee et al.   NATURE

Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors

(2012) Manuela Rossol et al.   Nature Communications

NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of gout

(2011) Flávio A. Amaral et al.   ARTHRITIS AND RHEUMATISM

The function of integrin-linked kinase in normal and activated stellate cells: implications for fibrogenesis in wound healing

(2011) Mahnoush S Shafiei et al.   LABORATORY INVESTIGATION

Protein Kinase D Signaling: Multiple Biological Functions in Health and Disease

(2011) Enrique Rozengurt   PHYSIOLOGY

ILK mediates LPS-induced vascular adhesion receptor expression and subsequent leucocyte trans-endothelial migration†

(2010) Sonsoles Hortelano et al.   CARDIOVASCULAR RESEARCH

The Chemokine Receptor CXCR2 Ligand KC (CXCL1) Mediates Neutrophil Recruitment and Is Critical for Development of Experimental Lyme Arthritis and Carditis

(2010) A. M. Ritzman et al.   INFECTION AND IMMUNITY

CXCL1 Regulates Pulmonary Host Defense to Klebsiella Infection via CXCL2, CXCL5, NF- B, and MAPKs

(2010) S. Cai et al.   JOURNAL OF IMMUNOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

IL-1 pathways in inflammation and human diseases

(2010) Cem Gabay et al.   Nature Reviews Rheumatology

IL-1β Processing in Host Defense: Beyond the Inflammasomes

(2010) Mihai G. Netea et al.   PLoS Pathogens

CCL5 Promotes Macrophage Recruitment and Survival in Human Adipose Tissue

(2009) Mayoura Keophiphath et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Integrin-linked kinase - essential roles in physiology and cancer biology

(2008) P. C. McDonald et al.   JOURNAL OF CELL SCIENCE

Expression and regulation of chemokines in mycobacterial infection

(2008) Patricia Méndez-Samperio   JOURNAL OF INFECTION

Interleukin-1β: a bridge between inflammation and excitotoxicity?

(2008) Birgit Fogal et al.   JOURNAL OF NEUROCHEMISTRY