Modeling of Frontotemporal Dementia Using iPSC Technology

MAPT mutations, tauopathy, and mechanisms of neurodegeneration

(2019) Kevin H. Strang et al.   LABORATORY INVESTIGATION

Genetics and molecular mechanisms of frontotemporal lobar degeneration: an update and future avenues

(2019) Ferrari Raffaele et al.   NEUROBIOLOGY OF AGING

Analysis of Frontotemporal Dementia, Amyotrophic Lateral Sclerosis, and Other Dementia-Related Genes in 107 Korean Patients with Frontotemporal Dementia

(2018) Eun-Joo Kim et al.   NEUROBIOLOGY OF AGING

Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice

(2018) Sander Beel et al.   Molecular Neurodegeneration

Progranulin-mediated deficiency of cathepsin D results in FTD and NCL-like phenotypes in neurons derived from FTD patients

(2017) Clarissa Valdez et al.   HUMAN MOLECULAR GENETICS

Current Advances and Limitations in Modeling ALS/FTD in a Dish Using Induced Pluripotent Stem Cells

(2017) Wenting Guo et al.   Frontiers in Neuroscience

Analyses MAPT, GRN, and C9orf72 mutations in Chinese patients with frontotemporal dementia

(2016) Min Tang et al.   NEUROBIOLOGY OF AGING

C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Demen

(2016) Ruxandra Dafinca et al.   STEM CELLS

High-Throughput Toxicity and Phenotypic Screening of 3D Human Neural Progenitor Cell Cultures on a Microarray Chip Platform

(2016) Gregory J. Nierode et al.   Stem Cell Reports

Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients withMAPTmutations

(2015) Mariangela Iovino et al.   BRAIN

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

Frontotemporal dementia

(2015) Jee Bang et al.   LANCET

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

(2015) Brian D. Freibaum et al.   NATURE

Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein

(2015) Marc Ehrlich et al.   Stem Cell Reports

Restoration of Progranulin Expression Rescues Cortical Neuron Generation in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia

(2015) Susanna Raitano et al.   Stem Cell Reports

Frontotemporal Lobar Degeneration: A Clinical Approach

(2014) Elissaios Karageorgiou et al.   SEMINARS IN NEUROLOGY

Clinical and genetic analysis of MAPT, GRN, and C9orf72 genes in Korean patients with frontotemporal dementia

(2013) Eun-Joo Kim et al.   NEUROBIOLOGY OF AGING

Genetic Correction of Tauopathy Phenotypes in Neurons Derived from Human Induced Pluripotent Stem Cells

(2013) Helen Fong et al.   Stem Cell Reports

TDP-43: gumming up neurons through protein–protein and protein–RNA interactions

(2012) Emanuele Buratti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects

(2012) Sandra Almeida et al.   Cell Reports

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

(2011) Katya Rascovsky et al.   BRAIN

Alzheimers Disease: Pathological Mechanisms and Recent Insights

(2011) Dana M. Niedowicz et al.   Current Neuropharmacology

TDP-43 and FUS: a nuclear affair

(2011) Dorothee Dormann et al.   TRENDS IN NEUROSCIENCES

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

(2010) C. Lagier-Tourenne et al.   HUMAN MOLECULAR GENETICS

Seoul Neuropsychological Screening Battery-Dementia Version (SNSB-D): A Useful Tool for Assessing and Monitoring Cognitive Impairments in Dementia Patients

(2010) Hyun-Jung Ahn et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia

(2010) Ian RA Mackenzie et al.   LANCET NEUROLOGY

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

(2008) Mototsugu Eiraku et al.   Cell Stem Cell