Tolerogenic dendritic cells impede priming of naïve CD8+T cells and deplete memory CD8+T cells

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients

(2011) N. Giannoukakis et al.   DIABETES CARE

Foxp3+ Regulatory T Cells Impede the Priming of Protective CD8+ T Cells

(2011) J. M. Ertelt et al.   JOURNAL OF IMMUNOLOGY

Transfer of Regulatory Properties from Tolerogenic to Proinflammatory Dendritic Cells via Induced Autoreactive Regulatory T Cells

(2011) F. S. Kleijwegt et al.   JOURNAL OF IMMUNOLOGY

Differential Protein Pathways in 1,25-Dihydroxyvitamin D3 and Dexamethasone Modulated Tolerogenic Human Dendritic Cells

(2011) Gabriela Bomfim Ferreira et al.   JOURNAL OF PROTEOME RESEARCH

New hope for immune intervention therapy in type 1 diabetes

(2011) Bart O Roep   LANCET

Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial

(2011) Tihamer Orban et al.   LANCET

Regulatory T Cells and IL-10 Independently Counterregulate Cytotoxic T Lymphocyte Responses Induced by Transcutaneous Immunization

(2011) Pamela Stein et al.   PLoS One

Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass

(2010) B. Keymeulen et al.   DIABETOLOGIA

UV irradiation of immunized mice induces type 1 regulatory T cells that suppress tumor antigen specific cytotoxic T lymphocyte responses

(2010) Masaaki Toda et al.   INTERNATIONAL JOURNAL OF CANCER

Critical Role for TNF in the Induction of Human Antigen-Specific Regulatory T Cells by Tolerogenic Dendritic Cells

(2010) F. S. Kleijwegt et al.   JOURNAL OF IMMUNOLOGY

Induction of Treg by monocyte-derived DC modulated by vitamin D3or dexamethasone: Differential role for PD-L1

(2009) Wendy W. J. Unger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antigen-specific Treg impair CD8+T-cell priming by blocking early T-cell expansion

(2009) Pascal Chappert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TLR Triggering on Tolerogenic Dendritic Cells Results in TLR2 Up-Regulation and a Reduced Proinflammatory Immune Program

(2009) S. Chamorro et al.   JOURNAL OF IMMUNOLOGY

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulatory T-Cell Suppression of CD8+ T-Cell-Mediated Graft-Versus-Host Reaction Requires Their Presence During Priming

(2009) Xiao-Nong Wang et al.   TRANSPLANTATION

Analysis of islet inflammation in human type 1 diabetes

(2008) A. Willcox et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes

(2008) Johnny Ludvigsson et al.   NEW ENGLAND JOURNAL OF MEDICINE