Evidence of Selection against Complex Mitotic-Origin Aneuploidy during Preimplantation Development

Tripolar mitosis in human cells and embryos: Occurrence, pathophysiology and medical implications

(2015) Beata Kalatova et al.   ACTA HISTOCHEMICA

Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates

(2015) Christian S Ottolini et al.   NATURE GENETICS

Common variants spanning PLK4 are associated with mitotic-origin aneuploidy in human embryos

(2015) R. C. McCoy et al.   SCIENCE

An unexpected finding: younger fathers have a higher risk for offspring with chromosomal aneuploidies

(2014) Bernhard Steiner et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Validation of multiple annealing and looping-based amplification cycle sequencing for 24-chromosome aneuploidy screening of cleavage-stage embryos

(2014) Jin Huang et al.   FERTILITY AND STERILITY

Blastulation rates decline in a linear fashion from euploid to aneuploid embryos with single versus multiple chromosomal errors

(2014) Mario Vega et al.   FERTILITY AND STERILITY

The origin, mechanisms, incidence and clinical consequences of chromosomal mosaicism in humans

(2014) Tyl H. Taylor et al.   HUMAN REPRODUCTION UPDATE

Aneuploidy across individual chromosomes at the embryonic level in trophectoderm biopsies: changes with patient age and chromosome structure

(2014) Jason M. Franasiak et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Genomic Imbalance in Products of Conception

(2014) Brynn Levy et al.   OBSTETRICS AND GYNECOLOGY

Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage

(2014) Judy FC Chow et al.   Reproductive Biology and Endocrinology

The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening

(2013) Jason M. Franasiak et al.   FERTILITY AND STERILITY

Blastocyst culture selects for euploid embryos: comparison of blastomere and trophectoderm biopsies

(2013) Alexis Adler et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Molecular origin of mitotic aneuploidies in preimplantation embryos

(2012) Eleni Mantikou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Multiple meiotic errors caused by predivision of chromatids in women of advanced maternal age undergoing in vitro fertilisation

(2012) Alan H Handyside et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Microarray analysis reveals abnormal chromosomal complements in over 70% of 14 normally developing human embryos

(2012) A. Mertzanidou et al.   HUMAN REPRODUCTION

Embryos whose polar bodies contain isolated reciprocal chromosome aneuploidy are almost always euploid

(2012) E. J. Forman et al.   HUMAN REPRODUCTION

Sequential comprehensive chromosome analysis on polar bodies, blastomeres and trophoblast: insights into female meiotic errors and chromosomal segregation in the preimplantation window of embryo development

(2012) A. Capalbo et al.   HUMAN REPRODUCTION

Chromoanagenesis and cancer: mechanisms and consequences of localized, complex chromosomal rearrangements

(2012) Andrew J Holland et al.   NATURE MEDICINE

Male infertility: Pathogenesis and clinical diagnosis

(2011) Csilla Krausz   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Is There a Paternal Age Effect for Aneuploidy?

(2011) K.G.L. Fonseka et al.   CYTOGENETIC AND GENOME RESEARCH

Aneuploidy in Human Spermatozoa

(2011) C. Templado et al.   CYTOGENETIC AND GENOME RESEARCH

Origins and rates of aneuploidy in human blastomeres

(2011) Matthew Rabinowitz et al.   FERTILITY AND STERILITY

Chromosomal mosaicism in human preimplantation embryos: a systematic review

(2011) Jannie van Echten-Arends et al.   HUMAN REPRODUCTION UPDATE

Prognostic value of triploid zygotes on intracytoplasmic sperm injection outcomes

(2011) Rita C. S. Figueira et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Comparison of aneuploidy frequencies between in vitro matured and unstimulated cycles oocytes by metaphase comparative genomic hybridization (mCGH)

(2011) Tahsin Yakut et al.   MOLECULAR BIOLOGY REPORTS

The genetic causes of male factor infertility: A review

(2010) Katherine L. O'Flynn O'Brien et al.   FERTILITY AND STERILITY

Comprehensive embryo analysis of advanced maternal age–related aneuploidies and mosaicism by short comparative genomic hybridization

(2010) Mariona Rius et al.   FERTILITY AND STERILITY

Preclinical validation of a microarray method for full molecular karyotyping of blastomeres in a 24-h protocol

(2010) D.S. Johnson et al.   HUMAN REPRODUCTION

The fate of the mosaic embryo: chromosomal constitution and development of Day 4, 5 and 8 human embryos

(2010) Margarida Avo Santos et al.   HUMAN REPRODUCTION

Increased responsiveness may be associated with tripronuclear embryos in both conventional in vitro fertilization and intracytoplasmic sperm injection cycles using gonadotropin-releasing hormone agonist long protocols: A self-matched observational study

(2010) Yong Jin Kim et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

SNP microarray-based 24 chromosome aneuploidy screening is significantly more consistent than FISH

(2010) N. R. Treff et al.   MOLECULAR HUMAN REPRODUCTION

Comprehensive analysis of karyotypic mosaicism between trophectoderm and inner cell mass

(2010) D.S. Johnson et al.   MOLECULAR HUMAN REPRODUCTION

Meiosis errors in over 20,000 oocytes studied in the practice of preimplantation aneuploidy testing

(2010) Anver Kuliev et al.   REPRODUCTIVE BIOMEDICINE ONLINE

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

Chromosome instability is common in human cleavage-stage embryos

(2009) Evelyne Vanneste et al.   NATURE MEDICINE

Preimplantation aneuploid embryos undergo self-correction in correlation with their developmental potential

(2008) Shiri Barbash-Hazan et al.   FERTILITY AND STERILITY

Chromosomal aneuploidy in embryos conceived with unstimulated cycle IVF

(2008) W. Verpoest et al.   HUMAN REPRODUCTION

Comprehensive molecular cytogenetic analysis of the human blastocyst stage

(2008) E. Fragouli et al.   HUMAN REPRODUCTION

Aneuploidy in the miscarriages of infertile women and the potential benefit of preimplanation genetic diagnosis

(2007) Ruth B. Lathi et al.   FERTILITY AND STERILITY