White matter alterations in Williams syndrome related to behavioral and motor impairments

Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelin alterations rescuable by a remyelinating drug

(2019) Boaz Barak et al.   NATURE NEUROSCIENCE

Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex

(2018) Ethan G. Hughes et al.   NATURE NEUROSCIENCE

A Different Brain: Anomalies of Functional and Structural Connections in Williams Syndrome

(2018) Chiara Gagliardi et al.   Frontiers in Neurology

The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development

(2018) Andrew T.N. Tebbenkamp et al.   CELL

Waves of Maturation and Senescence in Micro-structural MRI Markers of Human Cortical Myelination over the Lifespan

(2018) Håkon Grydeland et al.   CEREBRAL CORTEX

Changes in White Matter Microstructure Impact Cognition by Disrupting the Ability of Neural Assemblies to Synchronize

(2017) Sonya Bells et al.   JOURNAL OF NEUROSCIENCE

Effects of the mode of re-socialization after juvenile social isolation on medial prefrontal cortex myelination and function

(2017) Manabu Makinodan et al.   Scientific Reports

Surface-based morphometry reveals distinct cortical thickness and surface area profiles in Williams syndrome

(2016) Tamar Green et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Lesion remyelinating activity of GSK239512 versus placebo in patients with relapsing-remitting multiple sclerosis: a randomised, single-blind, phase II study

(2016) Caryl J. Schwartzbach et al.   JOURNAL OF NEUROLOGY

Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice

(2016) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Neurobiology of social behavior abnormalities in autism and Williams syndrome

(2016) Boaz Barak et al.   NATURE NEUROSCIENCE

Tamoxifen accelerates the repair of demyelinated lesions in the central nervous system

(2016) Ginez A. Gonzalez et al.   Scientific Reports

Non-steroidal anti-inflammatory drug indometacin enhances endogenous remyelination

(2015) Anna Preisner et al.   ACTA NEUROPATHOLOGICA

Altered white matter connectivity as a neural substrate for social impairment in Autism Spectrum Disorder

(2015) Stephanie H. Ameis et al.   CORTEX

Anti-Muscarinic Adjunct Therapy Accelerates Functional Human Oligodendrocyte Repair

(2015) K. Abiraman et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination

(2015) Jayshree Samanta et al.   NATURE

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

(2015) Fadi J. Najm et al.   NATURE

A new mechanism of nervous system plasticity: activity-dependent myelination

(2015) R. Douglas Fields   NATURE REVIEWS NEUROSCIENCE

SEMA4D compromises blood–brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease

(2015) Ernest S. Smith et al.   NEUROBIOLOGY OF DISEASE

Pivotal role of choline metabolites in remyelination

(2014) Thomas Skripuletz et al.   BRAIN

Dynamics of Oligodendrocyte Generation and Myelination in the Human Brain

(2014) Maggie S.Y. Yeung et al.   CELL

Myelin Formation and Remodeling

(2014) R. Douglas Fields   CELL

Progesterone and nestorone promote myelin regeneration in chronic demyelinating lesions of corpus callosum and cerebral cortex

(2014) Martine El-Etr et al.   GLIA

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

(2014) Feng Mei et al.   NATURE MEDICINE

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior

(2014) Yang Zhan et al.   NATURE NEUROSCIENCE

Motor skill learning requires active central myelination

(2014) I. A. McKenzie et al.   SCIENCE

Dynamic Regulation of Myelination in Health and Disease

(2014) Patrick Long et al.   JAMA Psychiatry

Altered Microstructure Within Social-Cognitive Brain Networks During Childhood in Williams Syndrome

(2013) Brian W. Haas et al.   CEREBRAL CORTEX

The role of myelin and oligodendrocytes in axonal energy metabolism

(2013) Aiman S Saab et al.   CURRENT OPINION IN NEUROBIOLOGY

A comparative study of the neuropsychiatric and neurocognitive phenotype in two microdeletion syndromes: Velocardiofacial (22q11.2 deletion) and Williams (7q11.23 deletion) syndromes

(2013) O. Zarchi et al.   EUROPEAN PSYCHIATRY

Systemic Lack of Canonical Histamine Receptor Signaling Results in Increased Resistance to Autoimmune Encephalomyelitis

(2013) N. Saligrama et al.   JOURNAL OF IMMUNOLOGY

Tocopherol Derivative TFA-12 Promotes Myelin Repair in Experimental Models of Multiple Sclerosis

(2013) B. Blanchard et al.   JOURNAL OF NEUROSCIENCE

Motor Skill Learning Induces Changes in White Matter Microstructure and Myelination

(2013) C. Sampaio-Baptista et al.   JOURNAL OF NEUROSCIENCE

A regenerative approach to the treatment of multiple sclerosis

(2013) Vishal A. Deshmukh et al.   NATURE

Estrogen receptor β ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis

(2013) Shalini Kumar et al.   NEUROBIOLOGY OF DISEASE

Regulation of conduction time along axons

(2013) A.H. Seidl   NEUROSCIENCE

Role of myelin plasticity in oscillations and synchrony of neuronal activity

(2013) S. Pajevic et al.   NEUROSCIENCE

PDGF is Required for Remyelination-Promoting IgM Stimulation of Oligodendrocyte Progenitor Cell Proliferation

(2013) Jens O. Watzlawik et al.   PLoS One

Prostacyclin promotes oligodendrocyte precursor recruitment and remyelination after spinal cord demyelination

(2013) C Takahashi et al.   Cell Death & Disease

Diosgenin promotes oligodendrocyte progenitor cell differentiation through estrogen receptor-mediated ERK1/2 activation to accelerate remyelination

(2012) Lin Xiao et al.   GLIA

Quetiapine prevents oligodendrocyte and myelin loss and promotes maturation of oligodendrocyte progenitors in the hippocampus of global cerebral ischemia mice

(2012) Xiaoying Bi et al.   JOURNAL OF NEUROCHEMISTRY

Plasticity in gray and white: neuroimaging changes in brain structure during learning

(2012) Robert J Zatorre et al.   NATURE NEUROSCIENCE

Impaired adult myelination in the prefrontal cortex of socially isolated mice

(2012) Jia Liu et al.   NATURE NEUROSCIENCE

A Critical Period for Social Experience-Dependent Oligodendrocyte Maturation and Myelination

(2012) M. Makinodan et al.   SCIENCE

Phenotypic psychiatric characterization of children with Williams syndrome and response of those with ADHD to methylphenidate treatment

(2011) Tamar Green et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Olesoxime accelerates myelination and promotes repair in models of demyelination

(2011) Karine Magalon et al.   ANNALS OF NEUROLOGY

Preliminary evidence of abnormal white matter related to the fusiform gyrus in Williams syndrome: a diffusion tensor imaging tractography study

(2011) B. W. Haas et al.   GENES BRAIN AND BEHAVIOR

Language and sociability: insights from Williams syndrome

(2011) Inna Fishman et al.   Journal of Neurodevelopmental Disorders

Alterations in diffusion properties of white matter in Williams syndrome

(2011) Lori R. Arlinghaus et al.   MAGNETIC RESONANCE IMAGING

White matter integrity deficits in prefrontal–amygdala pathways in Williams syndrome

(2011) Suzanne N. Avery et al.   NEUROIMAGE

Control of Local Protein Synthesis and Initial Events in Myelination by Action Potentials

(2011) H. Wake et al.   SCIENCE

The Williams syndrome: objective definition and diagnosis

(2010) M. Preus   CLINICAL GENETICS

Personality characteristics and behaviour problems in individuals of different ages with Williams syndrome

(2010) Angela Gosch et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Myelination in the human hippocampal formation from midgestation to adulthood

(2010) Hajnalka Ábrahám et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Myelination and support of axonal integrity by glia

(2010) Klaus-Armin Nave   NATURE

Retinoid X receptor gamma signaling accelerates CNS remyelination

(2010) Jeffrey K Huang et al.   NATURE NEUROSCIENCE

Myelination and the trophic support of long axons

(2010) Klaus-Armin Nave   NATURE REVIEWS NEUROSCIENCE

White-matter abnormalities in Tourette syndrome extend beyond motor pathways

(2010) Irene Neuner et al.   NEUROIMAGE

Williams–Beuren Syndrome

(2010) Barbara R. Pober   NEW ENGLAND JOURNAL OF MEDICINE

Cuprizone Demyelination of the Corpus Callosum in Mice Correlates with Altered Social Interaction and Impaired Bilateral Sensorimotor Coordination

(2009) Norah Hibbits et al.   ASN Neuro

Preliminary Evidence of White Matter Abnormality in the Uncinate Fasciculus in Generalized Social Anxiety Disorder

(2009) K. Luan Phan et al.   BIOLOGICAL PSYCHIATRY

White matter microstructural differences linked to left perisylvian language network in children with dyslexia

(2009) Sheryl L. Rimrodt et al.   CORTEX

Overlap With the Autism Spectrum in Young Children With Williams Syndrome

(2009) Bonita P. Klein-Tasman et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Training induces changes in white-matter architecture

(2009) Jan Scholz et al.   NATURE NEUROSCIENCE

What Is the Optimal Value of the g-Ratio for Myelinated Fibers in the Rat CNS? A Theoretical Approach

(2009) Taylor Chomiak et al.   PLoS One

Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate

(2009) V. Skihar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association between cerebral shape and social use of language in Williams syndrome

(2008) Doron Gothelf et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Brain structural differences associated with the behavioural phenotype in children with Williams syndrome

(2008) Linda E. Campbell et al.   BRAIN RESEARCH

Thyroid hormones promote differentiation of oligodendrocyte progenitor cells and improve remyelination after cuprizone-induced demyelination

(2008) P.G. Franco et al.   EXPERIMENTAL NEUROLOGY

Recovery from Chronic Demyelination by Thyroid Hormone Therapy: Myelinogenesis Induction and Assessment by Diffusion Tensor Magnetic Resonance Imaging

(2008) L.-A. Harsan et al.   JOURNAL OF NEUROSCIENCE

Reduced white matter integrity in attention-deficit hyperactivity disorder

(2008) Liberty S. Hamilton et al.   NEUROREPORT

White matter in learning, cognition and psychiatric disorders

(2008) R. Douglas Fields   TRENDS IN NEUROSCIENCES