Mineralocorticoid receptor antagonist‐mediated cognitive improvement in a mouse model of Alzheimer's type: possible involvement of BDNF‐H 2 S‐Nrf2 signaling

Insights into the Therapeutic Potential of Glucocorticoid Receptor Modulators for Neurodegenerative Diseases

(2020) Alejandro F. De Nicola et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oral Administration of Alpha Linoleic Acid Rescues Aβ-Induced Glia-Mediated Neuroinflammation and Cognitive Dysfunction in C57BL/6N Mice

(2020) Waqar Ali et al.   Cells

Mineralocorticoid receptor antagonists in essential and resistant hypertension

(2019) Konstantinos P. Imprialos et al.   CURRENT PHARMACEUTICAL DESIGN

Comparative efficacy and safety of mineralocorticoid receptor antagonists in heart failure: a network meta-analysis of randomized controlled trials

(2019) Pingping Yang et al.   HEART FAILURE REVIEWS

Hydrogen Sulfide Ameliorates Cognitive Dysfunction in Formaldehyde-Exposed Rats: Involvement in the Upregulation of Brain-Derived Neurotrophic Factor

(2019) Xiang Li et al.   NEUROPSYCHOBIOLOGY

Glucocorticoid receptors signaling impairment potentiates amyloid‐β oligomers‐induced pathology in an acute model of Alzheimer’s disease

(2019) Geoffrey Canet et al.   FASEB JOURNAL

Inadequate Expression and Activation of Mineralocorticoid Receptor Aggravates Spatial Memory Impairment after Traumatic Brain Injury

(2019) Bin Zhang et al.   NEUROSCIENCE

Hydrogen sulfide improves spatial memory impairment via increases of BDNF expression and hippocampal neurogenesis following early postnatal alcohol exposure

(2019) Fahimeh Mohseni et al.   PHYSIOLOGY & BEHAVIOR

Early Stroke Induces Long-Term Impairment of Adult Neurogenesis Accompanied by Hippocampal-Mediated Cognitive Decline

(2019) Carolin Kathner-Schaffert et al.   Cells

Estrogen deficiency exacerbates Aβ-induced memory impairment through enhancement of neuroinflammation, amyloidogenesis and NF-ĸB activation in ovariectomized mice

(2018) Jaesuk Yun et al.   BRAIN BEHAVIOR AND IMMUNITY

Circadian control of BDNF-mediated Nrf2 activation in astrocytes protects dopaminergic neurons from ferroptosis

(2018) Tetsuro Ishii et al.   FREE RADICAL BIOLOGY AND MEDICINE

Evidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer’s disease

(2018) Priscilla Youssef et al.   Scientific Reports

Spironolactone Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Rats

(2018) Wenjuan Liu et al.   Journal of Diabetes Research

Alzheimer's disease

(2017) C. A. Lane et al.   EUROPEAN JOURNAL OF NEUROLOGY

Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance

(2017) Tsutomu Wada et al.   JOURNAL OF ENDOCRINOLOGY

Exercise and BDNF reduce Aβ production by enhancing α-secretase processing of APP

(2017) Saket M. Nigam et al.   JOURNAL OF NEUROCHEMISTRY

Mineralocorticoid receptor associates with pro-inflammatory bias in the hippocampus of spontaneously hypertensive rats

(2017) M. E. Brocca et al.   JOURNAL OF NEUROENDOCRINOLOGY

The role of BDNF in Alzheimer's disease

(2017) Heikki Tanila   NEUROBIOLOGY OF DISEASE

Brain mineralocorticoid receptor function in control of salt balance and stress-adaptation

(2017) Edo Ronald de Kloet et al.   PHYSIOLOGY & BEHAVIOR

Administration of bovine casein-derived peptide prevents cognitive decline in Alzheimer disease model mice

(2017) Li-Juan Min et al.   PLoS One

Potential therapeutic action of natural products from traditional Chinese medicine on Alzheimer's disease animal models targeting neurotrophic factors

(2016) Shuyong Wei   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Neuroprotective Effect of Fisetin Against Amyloid-Beta-Induced Cognitive/Synaptic Dysfunction, Neuroinflammation, and Neurodegeneration in Adult Mice

(2016) Ashfaq Ahmad et al.   MOLECULAR NEUROBIOLOGY

Schisantherin B ameliorates Aβ 1–42 -induced cognitive decline via restoration of GLT-1 in a mouse model of Alzheimer's disease

(2016) Mengjie Xu et al.   PHYSIOLOGY & BEHAVIOR

Mechanisms of Aβ Clearance and Degradation by Glial Cells

(2016) Miriam Ries et al.   Frontiers in Aging Neuroscience

Chronic Stress and Glucocorticoids: From Neuronal Plasticity to Neurodegeneration

(2016) Sheela Vyas et al.   NEURAL PLASTICITY

Effect of mineralocorticoid receptor blockade on hippocampal-dependent memory in adults with obesity

(2015) Lisa S. Rotenstein et al.   Obesity

Spironolactone treatment attenuates vascular dysfunction in type 2 diabetic mice by decreasing oxidative stress and restoring NO/GC signaling

(2015) Marcondes A. B. Silva et al.   Frontiers in Physiology

Brain-Derived Neurotrophic Factor in Alzheimer’s Disease: Risk, Mechanisms, and Therapy

(2014) Jing-Hui Song et al.   MOLECULAR NEUROBIOLOGY

Prenatal Alcohol Exposure Modifies Glucocorticoid Receptor Subcellular Distribution in the Medial Prefrontal Cortex and Impairs Frontal Cortex-Dependent Learning

(2014) Andrea M. Allan et al.   PLoS One

Mineralocorticoid Receptor Blockade Prevents Stress-Induced Modulation of Multiple Memory Systems in the Human Brain

(2013) Lars Schwabe et al.   BIOLOGICAL PSYCHIATRY

Mifepristone Alters Amyloid Precursor Protein Processing to Preclude Amyloid Beta and Also Reduces Tau Pathology

(2013) David Baglietto-Vargas et al.   BIOLOGICAL PSYCHIATRY

Effects of TrkB agonist 7,8-dihydroxyflavone on sensory gating deficits in mice after administration of methamphetamine

(2013) Qian Ren et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Rapid colorimetric determination of reduced and oxidized glutathione using an end point coupled enzymatic assay

(2012) Mario Cappiello et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Eplerenone Reduced Lesion Size in Early but Not Advanced Atherosclerosis in Apolipoprotein E–Deficient Mice

(2012) Ayelet Raz-Pasteur et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Glucocorticoids Facilitate Astrocytic Amyloid-β Peptide Deposition by Increasing the Expression of APP and BACE1 and Decreasing the Expression of Amyloid-β-Degrading Proteases

(2011) Yanyan Wang et al.   ENDOCRINOLOGY

Mineralocorticoid receptors in the brain and cardiovascular regulation: minority rule?

(2011) Elise P. Gomez-Sanchez   TRENDS IN ENDOCRINOLOGY AND METABOLISM

11β-Hydroxysteroid dehydrogenases and the brain: From zero to hero, a decade of progress

(2010) Caitlin S. Wyrwoll et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Both mineralocorticoid and glucocorticoid receptors regulate emotional memory in mice

(2010) Ming Zhou et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Mineralocorticoid Receptor Overexpression in Basolateral Amygdala Reduces Corticosterone Secretion and Anxiety

(2009) Rupshi Mitra et al.   BIOLOGICAL PSYCHIATRY

Corticosteroids Operate as a Switch between Memory Systems

(2009) Lars Schwabe et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Stress-induced changes in corticosteroid receptor expression in primate hippocampus and prefrontal cortex

(2008) Paresh D. Patel et al.   PSYCHONEUROENDOCRINOLOGY