SHP‐1 ameliorates nonalcoholic steatohepatitis by inhibiting proinflammatory cytokine production

Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease

(2018) Juan Pablo Arab et al.   Annual Review of Pathology-Mechanisms of Disease

SHP-1 acts as a Tumor Suppressor in Hepatocarcinogenesis and HCC Progression

(2018) Liang-Zhi Wen et al.   CANCER RESEARCH

Non-alcoholic steatohepatitis pathogenesis: sublethal hepatocyte injury as a driver of liver inflammation

(2018) Samar H Ibrahim et al.   GUT

The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1

(2018) Chen-Hong Ding et al.   Molecular Cancer

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Triggering and resolution of inflammation in NASH

(2018) Susanne Schuster et al.   Nature Reviews Gastroenterology & Hepatology

Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver disease to hepatocarcinoma: Current and innovative therapeutic approaches

(2018) Antonella Borrelli et al.   Redox Biology

Of mice and men and NASH

(2018) David A. Brenner   HEPATOLOGY

Preclinical Models for Studying NASH-Driven HCC: How Useful Are They?

(2018) Mark A. Febbraio et al.   Cell Metabolism

Mouse models of nonalcoholic steatohepatitis Towards optimization of their relevance to human NASH

(2018) Geoff Farrell et al.   HEPATOLOGY

The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

(2018) Konstantin Kazankov et al.   Nature Reviews Gastroenterology & Hepatology

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

(2017) Naga Chalasani et al.   HEPATOLOGY

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

(2017) Zobair Younossi et al.   Nature Reviews Gastroenterology & Hepatology

Animal Models of Nonalcoholic Fatty Liver Disease—A Starter’s Guide

(2017) Mikhaïl Van Herck et al.   Nutrients

Hepatocyte SHP-1 is a Critical Modulator of Inflammation During Endotoxemia

(2017) Anupam Adhikari et al.   Scientific Reports

Lipocalin-2 mediates non-alcoholic steatohepatitis by promoting neutrophil-macrophage crosstalk via the induction of CXCR2

(2016) Dewei Ye et al.   JOURNAL OF HEPATOLOGY

An HNF1α-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatocytes and hepatic stellate cells

(2015) Hui Qian et al.   CELL RESEARCH

From NAFLD to NASH and HCC: Pathogenetic Mechanisms and Therapeutic Insights

(2013) Samuele De Minicis et al.   CURRENT PHARMACEUTICAL DESIGN

Hepatocyte-specificPtpn6deletion promotes hepatic lipid accretion, but reduces NAFLD in diet-induced obesity: Potential role of PPARγ

(2013) Elaine Xu et al.   HEPATOLOGY

Sophocarpine alleviates hepatocyte steatosis through activating AMPK signaling pathway

(2013) Chun-Yan Song et al.   TOXICOLOGY IN VITRO

The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology and the American Gastroenterological Association

(2012) Naga Chalasani et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Hepatocyte-Specific Ptpn6 Deletion Protects From Obesity-Linked Hepatic Insulin Resistance

(2012) E. Xu et al.   DIABETES

Inhibition of the Protein Tyrosine Phosphatase SHP-1 Increases Glucose Uptake in Skeletal Muscle Cells by Augmenting Insulin Receptor Signaling and GLUT4 Expression

(2011) Sébastien Bergeron et al.   ENDOCRINOLOGY

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

(2010) Eek Joong Park et al.   CELL

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Epidemiology of non-alcoholic fatty liver disease in China

(2008) Jian-Gao Fan et al.   JOURNAL OF HEPATOLOGY

Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1

(2008) Huazhang An et al.   NATURE IMMUNOLOGY