Thymic stromal lymphopoietin: its role and potential as a therapeutic target in asthma
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Thymic stromal lymphopoietin: its role and potential as a therapeutic target in asthma
Authors
Keywords
-
Journal
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume -, Issue -, Pages 1-16
Publisher
Informa UK Limited
Online
2020-06-22
DOI
10.1080/14728222.2020.1783242
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A thymic stromal lymphopoietin polymorphism may provide protection from asthma by altering gene expression
- (2020) Amy Moorehead et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Thymic stromal lymphopoietin epigenetically upregulates Fc receptor γ subunit–related receptors on antigen-presenting cells and induces TH2/TH17 polarization through dectin-2
- (2019) Yunsheng Liang et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Different endotypes and phenotypes drive the heterogeneity in severe asthma
- (2019) P. Jane McDowell et al. ALLERGY
- TSLP: from allergy to cancer
- (2019) Jonathan Corren et al. NATURE IMMUNOLOGY
- Aryl Hydrocarbon Receptor activation by diesel exhaust particles mediates epithelium-derived cytokines expression in severe allergic asthma
- (2018) Chih-Ming Weng et al. ALLERGY
- ILC2 frequency and activity are inhibited by glucocorticoid treatment via STAT pathway in patients with asthma
- (2018) Q.N Yu et al. ALLERGY
- The Expression of IL-33 and TSLP and Their Receptors in Asthmatic Airways Following Inhaled Allergen Challenge.
- (2018) Dhuha Al-Sajee et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Eosinophilic and Noneosinophilic Asthma
- (2018) Tara F. Carr et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Human Bronchial Epithelial Cell–derived Factors from Severe Asthmatic Subjects Stimulate Eosinophil Differentiation
- (2018) Brittany M. A. Salter et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Basophil Membrane Expression of Epithelial Cytokine Receptors in Patients with Severe Asthma
- (2018) Monica Boita et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Identification of MEK2 and CBX7 as Top Steroid Resistant Genes in Airway ILC2s and Lymphocytes from Asthma
- (2018) Kapil Sirohi et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Sputum autoantibodies in patients with severe eosinophilic asthma
- (2018) Manali Mukherjee et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Steroid resistance of airway type 2 innate lymphoid cells from patients with severe asthma: The role of thymic stromal lymphopoietin
- (2018) Sucai Liu et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Paucigranulocytic asthma: Uncoupling of airway obstruction from inflammation
- (2018) Omar Tliba et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Elevated Expression of IL-33 and TSLP in the Airways of Human Asthmatics In Vivo: A Potential Biomarker of Severe Refractory Disease
- (2018) Yan Li et al. JOURNAL OF IMMUNOLOGY
- Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma
- (2018) Mario Castro et al. NEW ENGLAND JOURNAL OF MEDICINE
- TSLP signaling in CD4+T cells programs a pathogenic T helper 2 cell state
- (2018) Yrina Rochman et al. Science Signaling
- Characterization of signaling pathways regulating the expression of pro-inflammatory long form thymic stromal lymphopoietin upon human metapneumovirus infection
- (2018) Youxian Li et al. Scientific Reports
- TSLP signaling in CD4+T cells programs a pathogenic T helper 2 cell state
- (2018) Yrina Rochman et al. Science Signaling
- Thymic Stromal Lymphopoietin Isoforms, Inflammatory Disorders, and Cancer
- (2018) Gilda Varricchi et al. Frontiers in Immunology
- Anti-IL-7 receptor α monoclonal antibody (GSK2618960) in healthy subjects - a randomised, double-blind placebo-controlled study
- (2018) Joanne Ellis et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Systematic literature review of the clinical, humanistic, and economic burden associated with asthma uncontrolled by GINA Steps 4 or 5 treatment
- (2018) Stephanie Chen et al. CURRENT MEDICAL RESEARCH AND OPINION
- Bronchial Allergen Challenge of Patients with Atopic Asthma Triggers an Alarmin (IL-33, TSLP, and IL-25) Response in the Airways Epithelium and Submucosa
- (2018) Wei Wang et al. JOURNAL OF IMMUNOLOGY
- TSLP promotes asthmatic airway remodeling via p38-STAT3 signaling pathway in human lung fibroblast
- (2018) Liuzhao Cao et al. EXPERIMENTAL LUNG RESEARCH
- Dupilumab safety and efficacy in uncontrolled asthma: a systematic review and meta-analysis of randomized clinical trials
- (2018) Yazan Zayed et al. JOURNAL OF ASTHMA
- Exosomes from Thymic Stromal Lymphopoietin-Activated Dendritic Cells Promote Th2 Differentiation through the OX40 Ligand
- (2018) Li Huang et al. PATHOBIOLOGY
- Thymic stromal lymphopoietin and apocynin alter the expression of airway remodeling factors in human rhinovirus-infected cells
- (2017) Joanna Wieczfinska et al. IMMUNOBIOLOGY
- The significance of the levels of IL-4, IL-31 and TLSP in patients with asthma and/or rhinitis
- (2017) Ruonan Chai et al. Immunotherapy
- Proprotein convertases generate a highly functional heterodimeric form of thymic stromal lymphopoietin in humans
- (2017) Julie A. Poposki et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Long form of thymic stromal lymphopoietin of keratinocytes is induced by protein allergens
- (2017) Yasutaka Kuroda et al. Journal of Immunotoxicology
- Tezepelumab in Adults with Uncontrolled Asthma
- (2017) Jonathan Corren et al. NEW ENGLAND JOURNAL OF MEDICINE
- Characteristics associated with clinical severity and inflammatory phenotype of naturally occurring virus-induced exacerbations of asthma in adults
- (2017) Asger Bjerregaard et al. RESPIRATORY MEDICINE
- Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma
- (2017) Kenneth Verstraete et al. Nature Communications
- Impact of chronic rhinosinusitis on severe asthma patients
- (2017) Ta-Jen Lee et al. PLoS One
- Overlap of atopic, eosinophilic, and TH2-high asthma phenotypes in a general population with current asthma
- (2016) Trung N. Tran et al. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
- Increased expression of thymic stromal lymphopoietin in induced sputum from asthmatic children
- (2016) Anissa Berraïes et al. IMMUNOLOGY LETTERS
- Increased Levels of Interleukin-33 and Thymic Stromal Lymphopoietin in Exhaled Breath Condensate in Chronic Bronchial Asthma
- (2016) Joanna Glück et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia
- (2016) Steven G. Smith et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Thymic stromal lymphopoietin controls prostaglandin D 2 generation in patients with aspirin-exacerbated respiratory disease
- (2016) Kathleen M. Buchheit et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis
- (2016) Christoph S N Klose et al. NATURE IMMUNOLOGY
- Distinct roles of short and long thymic stromal lymphopoietin isoforms in house dust mite-induced asthmatic airway epithelial barrier disruption
- (2016) Hangming Dong et al. Scientific Reports
- TSLP production by dendritic cells is modulated by IL-1β and components of the endoplasmic reticulum stress response
- (2015) Matthew J. Elder et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Translational value of animal models of asthma: Challenges and promises
- (2015) Seil Sagar et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33
- (2015) Christina A. Christianson et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Thymic stromal lymphopoietin and IL-33 modulate migration of hematopoietic progenitor cells in patients with allergic asthma
- (2015) Steven G. Smith et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Coexpression of type 2 immune targets in sputum-derived epithelial and dendritic cells from asthmatic subjects
- (2015) Bertram Bleck et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Thymic stromal lymphopoietin activation of basophils in patients with allergic asthma is IL-3 dependent
- (2015) Brittany M. Salter et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Dichotomy of short and long thymic stromal lymphopoietin isoforms in inflammatory disorders of the bowel and skin
- (2015) Giulia Fornasa et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Correlation of TSLP, IL-33, and CD4 + CD25 + FOXP3 + T regulatory (Treg) in pediatric asthma
- (2015) Anil Chauhan et al. JOURNAL OF ASTHMA
- Myeloid dendritic cells are primed in allergic asthma for thymic stromal lymphopoietin-mediated induction of Th2 and Th9 responses
- (2014) A. Froidure et al. ALLERGY
- IL-17 in Severe Asthma. Where Do We Stand?
- (2014) Julie Chesné et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Infection with human rhinovirus 16 promotes enhanced IgE responsiveness in basophils of atopic asthmatics
- (2014) R. Agrawal et al. CLINICAL AND EXPERIMENTAL ALLERGY
- T cell-mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells
- (2014) C. C. K. Hui et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Activation of TRPV1 mediates thymic stromal lymphopoietin release via the Ca2+/NFAT pathway in airway epithelial cells
- (2014) Xinying Jia et al. FEBS LETTERS
- The Genetic Variants of Thymic Stromal Lymphopoietin Protein in Children with Asthma and Allergic Rhinitis
- (2014) Esra Birben et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Enhanced innate type 2 immune response in peripheral blood from patients with asthma
- (2014) Kathleen R. Bartemes et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Expression and Cellular Provenance of Thymic Stromal Lymphopoietin and Chemokines in Patients with Severe Asthma and Chronic Obstructive Pulmonary Disease
- (2014) S. Ying et al. JOURNAL OF IMMUNOLOGY
- Thymic stromal lymphopoietin (TSLP) secretion from human nasal epithelium is a function of TSLP genotype
- (2014) C C K Hui et al. Mucosal Immunology
- The short form of TSLP is constitutively translated in human keratinocytes and has characteristics of an antimicrobial peptide
- (2014) L Bjerkan et al. Mucosal Immunology
- Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses
- (2014) Gail M. Gauvreau et al. NEW ENGLAND JOURNAL OF MEDICINE
- Directional Secretory Response of Double Stranded RNA-Induced Thymic Stromal Lymphopoetin (TSLP) and CCL11/Eotaxin-1 in Human Asthmatic Airways
- (2014) Gustavo Nino et al. PLoS One
- Exploring the Effects of Omalizumab in Allergic Asthma
- (2013) Nicola A. Hanania et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Development and function of group 2 innate lymphoid cells
- (2013) Jennifer A Walker et al. CURRENT OPINION IN IMMUNOLOGY
- International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
- (2013) K. F. Chung et al. EUROPEAN RESPIRATORY JOURNAL
- TNF-α–mediated bronchial barrier disruption and regulation by src-family kinase activation
- (2013) Michelle A. Hardyman et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Thymic stromal lymphopoietin activity is increased in nasal polyps of patients with chronic rhinosinusitis
- (2013) Deepti R. Nagarkar et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis
- (2013) Wendy C. Moore et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Central Role of Cellular Senescence in TSLP-Induced Airway Remodeling in Asthma
- (2013) Jinxiang Wu et al. PLoS One
- Thymic Stromal Lymphopoietin Induces Migration in Human Airway Smooth Muscle Cells
- (2013) Naresh Singh Redhu et al. Scientific Reports
- Mast Cell-Activated Bone Marrow Mesenchymal Stromal Cells Regulate Proliferation and Lineage Commitment of CD34+ Progenitor Cells
- (2013) Zoulfia Allakhverdi et al. Frontiers in Immunology
- Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps
- (2012) M. Morshed et al. ALLERGY
- Elevated Epidermal Thymic Stromal Lymphopoietin Levels Establish an Antitumor Environment in the Skin
- (2012) Shadmehr Demehri et al. CANCER CELL
- Thymic stromal lymphopoietin promotes asthmatic airway remodelling in human lung fibroblast cells through STAT3 signalling pathway
- (2012) Jinxiang Wu et al. CELL BIOCHEMISTRY AND FUNCTION
- Toll-like receptors 2, 3 and 4 and thymic stromal lymphopoietin expression in fatal asthma
- (2012) D. S. Ferreira et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Functions of thymic stromal lymphopoietin in immunity and disease
- (2012) Yanlu Zhang et al. IMMUNOLOGIC RESEARCH
- Allergen Induces Dual Upregulation of TSLP Receptor on Circulating Basophils and Dendritic Cells in Atopic Dermatitis
- (2012) R. Agrawal et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Airway epithelial cells activate TH2 cytokine production in mast cells through IL-1 and thymic stromal lymphopoietin
- (2012) Deepti R. Nagarkar et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Long TSLP transcript expression and release of TSLP induced by TLR ligands and cytokines in human keratinocytes
- (2012) Yang Xie et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Asthma phenotypes: the evolution from clinical to molecular approaches
- (2012) Sally E Wenzel NATURE MEDICINE
- Mast Cell-Airway Smooth Muscle Crosstalk
- (2011) Davinder Kaur et al. CHEST
- Function and mechanisms of TSLP/TSLPR complex in asthma and COPD
- (2011) N. S. Redhu et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Thymic stromal lymphopoietin is expressed and produced by caspase-1/NF-κB pathway in mast cells
- (2011) Phil-Dong Moon et al. CYTOKINE
- TSLP enhances the function of helper type 2 cells
- (2011) Masayuki Kitajima et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Human thymic stromal lymphopoietin enhances expression of CD80 in human CD14+ monocytes/macrophages
- (2011) Reiji Hirano et al. INFLAMMATION RESEARCH
- Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma
- (2011) Aarti Shikotra et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Thymic Stromal Lymphopoietin Is Produced by Dendritic Cells
- (2011) M. Kashyap et al. JOURNAL OF IMMUNOLOGY
- TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation
- (2011) Mark C. Siracusa et al. NATURE
- Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population
- (2011) Tomomitsu Hirota et al. NATURE GENETICS
- Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations
- (2011) Carole Ober et al. NATURE GENETICS
- TSLP polymorphisms are associated with asthma in a sex-specific fashion
- (2010) G. M. Hunninghake et al. ALLERGY
- Essential role of NF-κB and AP-1 transcription factors in TNF-α-induced TSLP expression in human airway smooth muscle cells
- (2010) Naresh Singh Redhu et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- β2-Adrenoceptor Agonists Enhance Cytokine-Induced Release of Thymic Stromal Lymphopoietin by Lung Tissue Cells
- (2010) Kyoko Futamura et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Thymic stromal lymphopoietin–induced human asthmatic airway epithelial cell proliferation through an IL-13–dependent pathway
- (2010) Abdelhabib Semlali et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Thymic Stromal Lymphopoietin in Cigarette Smoke-Exposed Human Airway Smooth Muscle
- (2010) D. F. Smelter et al. JOURNAL OF IMMUNOLOGY
- Thymic Stromal Lymphopoietin-Activated Plasmacytoid Dendritic Cells Induce the Generation of FOXP3+ Regulatory T Cells in Human Thymus
- (2010) S. Hanabuchi et al. JOURNAL OF IMMUNOLOGY
- Thymic Stromal Lymphopoietin Receptor-Mediated IL-6 and CC/CXC Chemokines Expression in Human Airway Smooth Muscle Cells: Role of MAPKs (ERK1/2, p38, and JNK) and STAT3 Pathways
- (2010) L. Shan et al. JOURNAL OF IMMUNOLOGY
- A Large-Scale, Consortium-Based Genomewide Association Study of Asthma
- (2010) Miriam F. Moffatt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Distinct Signal Codes Generate Dendritic Cell Functional Plasticity
- (2010) K. Arima et al. Science Signaling
- Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon- in bronchial epithelial cells from donors with asthma
- (2010) L. Uller et al. THORAX
- T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma
- (2009) Prescott G. Woodruff et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Thymic Stromal Lymphopoietin Induces Chemotactic and Prosurvival Effects in Eosinophils
- (2009) Chun K. Wong et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Fc RI-mediated thymic stromal lymphopoietin production by interleukin-4-primed human mast cells
- (2009) Y. Okayama et al. EUROPEAN RESPIRATORY JOURNAL
- A thymic stromal lymphopoietin gene variant is associated with asthma and airway hyperresponsiveness
- (2009) Jian-Qing He et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Thymic stromal lymphopoietin as a mediator of crosstalk between bronchial smooth muscles and mast cells
- (2009) Zoulfia Allakhverdi et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Consistency of sputum eosinophilia in difficult-to-treat asthma: A 5-year follow-up study
- (2009) Ilonka H. van Veen et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Functional Analysis of the Thymic Stromal Lymphopoietin Variants in Human Bronchial Epithelial Cells
- (2008) Michishige Harada et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Human TSLP and TLR3 ligands promote differentiation of Th17 cells with a central memory phenotype under Th2-polarizing conditions
- (2008) J. Tanaka et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Human TSLP directly enhances expansion of CD8+T cells
- (2008) T. Akamatsu et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- CD34+ hemopoietic progenitor cells are potent effectors of allergic inflammation
- (2008) Zoulfia Allakhverdi et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now