Cell-laden alginate hydrogels for the treatment of diabetes

Recent advances in genome editing of stem cells for drug discovery and therapeutic application

(2020) Jaesuk Lee et al.   PHARMACOLOGY & THERAPEUTICS

Type 1 diabetes—early life origins and changing epidemiology

(2020) Jill M Norris et al.   Lancet Diabetes & Endocrinology

Stem Cell Therapy for Diabetes: Beta Cells versus Pancreatic Progenitors

(2020) Bushra Memon et al.   Cells

Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure

(2020) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Long-term, targeted delivery of GDNF from encapsulated cells is neuroprotective and reduces seizures in the pilocarpine model of epilepsy

(2019) Giovanna Paolone et al.   JOURNAL OF NEUROSCIENCE

Mathematical predictions of oxygen availability in micro‐ and macro‐encapsulated human and porcine pancreatic islets

(2019) Rui Cao et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Polymeric Approaches to Reduce Tissue Responses Against Devices Applied for Islet-Cell Encapsulation

(2019) Shuixan Hu et al.   Frontiers in Bioengineering and Biotechnology

An Atmosphere‐Breathing Refillable Biphasic Device for Cell Replacement Therapy

(2019) Duo An et al.   ADVANCED MATERIALS

Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation

(2019) Qingsheng Liu et al.   Nature Communications

Cell encapsulation: Overcoming barriers in cell transplantation in diabetes and beyond

(2018) Marco Farina et al.   ADVANCED DRUG DELIVERY REVIEWS

Engineering a Clinically Translatable Bioartificial Pancreas to Treat Type I Diabetes

(2018) Gorka Orive et al.   TRENDS IN BIOTECHNOLOGY

Collagen type VI interaction improves human islet survival in immunoisolating microcapsules for treatment of diabetes

(2018) L. Alberto Llacua et al.   Islets

Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply

(2018) Yoav Evron et al.   Scientific Reports

Microencapsulated adult porcine islets transplanted intraperitoneally in streptozotocin-diabetic non-human primates

(2018) Susan A. Safley et al.   XENOTRANSPLANTATION

An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport

(2017) Shang Song et al.   LAB ON A CHIP

Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes

(2017) Barbara Ludwig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice

(2016) Arturo J Vegas et al.   NATURE MEDICINE

Clinical Benefit of Islet Xenotransplantation for the Treatment of Type 1 Diabetes

(2016) Shinichi Matsumoto et al.   EBioMedicine

The role of genetically engineered pigs in xenotransplantation research

(2015) David KC Cooper et al.   JOURNAL OF PATHOLOGY

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Encapsulation of porcine pancreatic islets within an immunoprotective capsule comprising methacrylated glycol chitosan and alginate

(2014) Anna Louise Hillberg et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Differentiated human stem cells resemble fetal, not adult, β cells

(2014) Sinisa Hrvatin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis and Phase Behavior of Poly(N-isopropylacrylamide)-b- Poly(L-Lysine Hydrochloride) and Poly(N-Isopropylacrylamide- co-Acrylamide)-b-Poly(L-Lysine Hydrochloride)

(2014) Milica Spasojević et al.   Materials

Microencapsulation of cells, including islets, within stable ultra-thin membranes of maleimide-conjugated PEG-lipid with multifunctional crosslinkers

(2013) Yuji Teramura et al.   BIOMATERIALS

Enhanced Oxygen Supply Improves Islet Viability in a New Bioartificial Pancreas

(2013) Uriel Barkai et al.   CELL TRANSPLANTATION

Insulin-producing Surrogate β-cells From Embryonic Stem Cells: Are We There Yet?

(2011) Ortwin Naujok et al.   MOLECULAR THERAPY

Bioartificial pancreas☆Microencapsulation and conformal coating of islet of Langerhans

(2010) Yuji Teramura et al.   ADVANCED DRUG DELIVERY REVIEWS

Treatment of insulin dependent diabetes mellitus with intravascular transplantation of pancreatic islet cells without immunosuppressive therapy

(2009) A Prochorov et al.   Advances in Medical Sciences