Morroniside attenuates high glucose–induced BMSC dysfunction by regulating the Glo1/AGE/RAGE axis

RAGE Signaling in Skeletal Biology

(2019) Lilian I. Plotkin et al.   Current Osteoporosis Reports

Impaired Bone Regenerative Effect of Exosomes Derived from Bone Marrow Mesenchymal Stem Cells in Type 1 Diabetes

(2019) Yu Zhu et al.   Stem Cells Translational Medicine

Bone Morphogenetic Protein-6 Attenuates Type 1 Diabetes Mellitus-Associated Bone Loss

(2019) Jesse F. Wang et al.   Stem Cells Translational Medicine

Hesperetin ameliorates diabetic nephropathy in rats by activating Nrf2/ARE/glyoxalase 1 pathway

(2019) Ya-Jing Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Norepinephrine protects against apoptosis of mesenchymal stem cells induced by high glucose

(2019) Yanan Kong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Blockade of receptors of advanced glycation end products ameliorates diabetic osteogenesis of adipose-derived stem cells through DNA methylation and Wnt signalling pathway

(2018) Maorui Zhang et al.   CELL PROLIFERATION

Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes

(2018) Hema Kalyanaraman et al.   DIABETES

Irbesartan attenuates advanced glycation end products-mediated damage in diabetes-associated osteoporosis through the AGEs/RAGE pathway

(2018) Yan-Zhen Cheng et al.   LIFE SCIENCES

Corni Fructus: a review of chemical constituents and pharmacological activities

(2018) Yu Dong et al.   Chinese Medicine

Diagnosis and management of bone fragility in diabetes: an emerging challenge

(2018) S.L. Ferrari et al.   OSTEOPOROSIS INTERNATIONAL

Dysregulation of Nrf2/Keap1 Redox Pathway in Diabetes Affects Multipotency of Stromal Cells

(2018) Piul S. Rabbani et al.   DIABETES

Therapeutic options to reduce advanced glycation end products in patients with diabetes mellitus: A review

(2018) Philipp Jud et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Enhancement of bone regeneration with the accordion technique via HIF-1α/VEGF activation in a rat distraction osteogenesis model

(2017) Jia Xu et al.   Journal of Tissue Engineering and Regenerative Medicine

Combination of Morroniside and Diosgenin Prevents High Glucose-Induced Cardiomyocytes Apoptosis

(2017) Wen-Xia Pi et al.   MOLECULES

High glucose prevents osteogenic differentiation of mesenchymal stem cells via lncRNA AK028326/CXCL13 pathway

(2016) Boran Cao et al.   BIOMEDICINE & PHARMACOTHERAPY

Methylglyoxal-induced dicarbonyl stress in aging and disease: first steps towards glyoxalase 1-based treatments

(2016) N. Rabbani et al.   CLINICAL SCIENCE

Mechanisms of diabetes mellitus-induced bone fragility

(2016) Nicola Napoli et al.   Nature Reviews Endocrinology

Effect of morroniside on glomerular mesangial cells through AGE–RAGE pathway

(2016) Gaohong Lv et al.   Human Cell

Epidemiology of Skeletal Health in Type 1 Diabetes

(2016) David R. Weber et al.   Current Osteoporosis Reports

AGEs Induce Apoptosis in Rat Osteoblast Cells by Activating the Caspase-3 Signaling Pathway Under a High-Glucose Environment In Vitro

(2015) Jiaqiang Liu et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Type 1 Diabetes Is Associated With an Increased Risk of Fracture Across the Life Span: A Population-Based Cohort Study Using The Health Improvement Network (THIN)

(2015) David R. Weber et al.   DIABETES CARE

Type 1 diabetes and risk of fracture: meta-analysis and review of the literature

(2015) V. N. Shah et al.   DIABETIC MEDICINE

High glucose microenvironments inhibit the proliferation and migration of bone mesenchymal stem cells by activating GSK3β

(2015) Bo Zhang et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Comparative pharmacokinetics of the main compounds of Shanzhuyu extract after oral administration in normal and chronic kidney disease rats

(2015) Min Zhao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Diabetes and Its Effect on Bone and Fracture Healing

(2015) Hongli Jiao et al.   Current Osteoporosis Reports

Selective Therapeutic Effect of Cornus officinalis Fruits on the Damage of Different Organs in STZ-Induced Diabetic Rats

(2014) Yunkyung Han et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Advanced Glycation End Product 3 (AGE3) Suppresses the Mineralization of Mouse Stromal ST2 Cells and Human Mesenchymal Stem Cells by Increasing TGF-β Expression and Secretion

(2014) Masakazu Notsu et al.   ENDOCRINOLOGY

The effects of Liuwei Dihuang on canonical Wnt/β-catenin signaling pathway in osteoporosis

(2014) Bingjiang Xia et al.   JOURNAL OF ETHNOPHARMACOLOGY

AGEs induce caspase-mediated apoptosis of rat BMSCs via TNFα production and oxidative stress

(2013) Evgeny Weinberg et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Differential regulation of the apoptotic machinery during megakaryocyte differentiation and platelet production by inhibitor of apoptosis protein Livin

(2013) I Abd-Elrahman et al.   Cell Death & Disease

Evaluation of Morroniside, Iridoid Glycoside from Corni Fructus, on Diabetes-Induced Alterations such as Oxidative Stress, Inflammation, and Apoptosis in the Liver of Type 2 Diabetic db/db Mice

(2011) Chan Hum Park et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Neuroprotective effect of morroniside on focal cerebral ischemia in rats

(2010) Wen Wang et al.   BRAIN RESEARCH BULLETIN

Diabetes Induced Changes in Rat Mesenchymal Stem Cells

(2010) Alexandra Stolzing et al.   CELLS TISSUES ORGANS

The Beneficial Effects of Morroniside on the Inflammatory Response and Lipid Metabolism in the Liver of db/db Mice

(2009) Chan Hum Park et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Inhibition of osteoblastic bone formation by nuclear factor-κB

(2009) Jia Chang et al.   NATURE MEDICINE

HMGB1 Regulates RANKL-Induced Osteoclastogenesis in a Manner Dependent on RAGE

(2008) Zheng Zhou et al.   JOURNAL OF BONE AND MINERAL RESEARCH