SIRT1 relieves Necrotizing Enterocolitis through inactivation of Hypoxia-inducible factor (HIF)-1a

Sirt1-hypoxia-inducible factor-1α interaction is a key mediator of tubulointerstitial damage in the aged kidney

(2019) Dong Ryeol Ryu et al.   AGING CELL

Activation of SIRT1 ameliorates LPS-induced lung injury in mice via decreasing endothelial tight junction permeability

(2018) Cuiping Fu et al.   ACTA PHARMACOLOGICA SINICA

Marked differences in tight junction composition and macromolecular permeability among different intestinal cell types

(2018) Sarah C. Pearce et al.   BMC BIOLOGY

Regulatory mechanisms of hypoxia-inducible factor 1 activity: Two decades of knowledge

(2018) Sho Koyasu et al.   CANCER SCIENCE

SIRT1 activation by resveratrol reduces brain edema and neuronal apoptosis in an experimental rat subarachnoid hemorrhage model

(2017) Cong Qian et al.   Molecular Medicine Reports

Intestinal tight junctions are severely altered in NEC preterm neonates

(2017) Amir Bein et al.   Pediatrics and Neonatology

LPS Induces Hyper-Permeability of Intestinal Epithelial Cells

(2016) Amir Bein et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Necrotizing enterocolitis: new insights into pathogenesis and mechanisms

(2016) Diego F. Niño et al.   Nature Reviews Gastroenterology & Hepatology

Protective Effects of Bifidobacterium on Intestinal Barrier Function in LPS-Induced Enterocyte Barrier Injury of Caco-2 Monolayers and in a Rat NEC Model

(2016) Xiang Ling et al.   PLoS One

Protective effects of baicalin on LPS-induced injury in intestinal epithelial cells and intercellular tight junctions

(2015) Jian Chen et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Increases in peripheral SIRT1: A new biological characteristic of asthma

(2015) Yajun Wang et al.   RESPIROLOGY

The relationship between serum hypoxia-inducible factor 1α and coronary artery calcification in asymptomatic type 2 diabetic patients

(2014) Gang Li et al.   Cardiovascular Diabetology

Sirtuin1: A Promising Serum Protein Marker for Early Detection of Alzheimer’s Disease

(2013) Rahul Kumar et al.   PLoS One

Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions

(2012) Alexander Laemmle et al.   PLoS One

Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma

(2012) TOMOMI ICHIKAWA et al.   RESPIROLOGY

Sirtuin 1 in lipid metabolism and obesity

(2011) Thaddeus T. Schug et al.   ANNALS OF MEDICINE

HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury

(2010) Rena Feinman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1α via upregulation of VHL in a colon cancer cell line

(2010) Kyeong Lee et al.   BIOCHEMICAL PHARMACOLOGY

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease

(2008) Carl Julien et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY