Opposing effects of antibiotics and germ-free status on neuropeptide systems involved in social behaviour and pain regulation

The role of the microbiome in the neurobiology of social behaviour

(2020) Amar Sarkar et al.   BIOLOGICAL REVIEWS

Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice

(2018) F. Guida et al.   BRAIN BEHAVIOR AND IMMUNITY

Antibiotic-induced dysbiosis effects on the murine gastrointestinal tract and their systemic repercussions

(2018) Caio Pupin Rosa et al.   LIFE SCIENCES

Why does the microbiome affect behaviour?

(2018) Katerina V.-A. Johnson et al.   NATURE REVIEWS MICROBIOLOGY

Opioid receptors: drivers to addiction?

(2018) Emmanuel Darcq et al.   NATURE REVIEWS NEUROSCIENCE

Postnatal colonization with human "infant-type" Bifidobacterium species alters behavior of adult gnotobiotic mice

(2018) Berkley Luk et al.   PLoS One

Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism

(2018) Amir Zarrinpar et al.   Nature Communications

Social interaction-induced activation of RNA splicing in the amygdala of microbiome-deficient mice

(2018) Roman M Stilling et al.   eLife

Microbiota influence the development of the brain and behaviors in C57BL/6J mice

(2018) Jing Lu et al.   PLoS One

A microbial signature of psychological distress in irritable bowel syndrome

(2018) Johannes Peter et al.   PSYCHOSOMATIC MEDICINE

Mouse Microbiota Models: Comparing Germ-Free Mice and Antibiotics Treatment as Tools for Modifying Gut Bacteria

(2018) Elizabeth A. Kennedy et al.   Frontiers in Physiology

Prefrontal cortical control of a brainstem social behavior circuit

(2017) Tamara B Franklin et al.   NATURE NEUROSCIENCE

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

Social connectedness, mental health and the adolescent brain

(2017) M. Lamblin et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides

(2017) Gilliard Lach et al.   Neurotherapeutics

The gut microbiota as a key regulator of visceral pain

(2017) Siobhain M. Oʼ Mahony et al.   PAIN

Variation in the β-endorphin, oxytocin, and dopamine receptor genes is associated with different dimensions of human sociality

(2017) Eiluned Pearce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

(2017) Sophie Leclercq et al.   Nature Communications

Sex-related alterations of gut microbiota composition in the BTBR mouse model of autism spectrum disorder

(2017) Lorena Coretti et al.   Scientific Reports

Bifidobacterium brevereduces apoptotic epithelial cell shedding in an exopolysaccharide and MyD88-dependent manner

(2017) K. R. Hughes et al.   Open Biology

Antibiotic Driven Changes in Gut Motility Suggest Direct Modulation of Enteric Nervous System

(2017) Thilini Delungahawatta et al.   Frontiers in Neuroscience

Antibiotics in the first year of life and subsequent neurocognitive outcomes

(2016) Rebecca F. Slykerman et al.   ACTA PAEDIATRICA

Moody microbes or fecal phrenology: what do we know about the microbiota-gut-brain axis?

(2016) Paul Forsythe et al.   BMC Medicine

Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication

(2016) Esther E. Fröhlich et al.   BRAIN BEHAVIOR AND IMMUNITY

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

The Central Nervous System and the Gut Microbiome

(2016) Gil Sharon et al.   CELL

The Host Shapes the Gut Microbiota via Fecal MicroRNA

(2016) Shirong Liu et al.   Cell Host & Microbe

Antibiotic-associated encephalopathy

(2016) Shamik Bhattacharyya et al.   NEUROLOGY

Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat

(2016) A.E. Hoban et al.   NEUROSCIENCE

Fetal, neonatal, and infant microbiome: Perturbations and subsequent effects on brain development and behavior

(2016) Rochellys Diaz Heijtz   Seminars in Fetal & Neonatal Medicine

Regulation of prefrontal cortex myelination by the microbiota

(2016) A E Hoban et al.   Translational Psychiatry

Pain tolerance predicts human social network size

(2016) Katerina V.-A. Johnson et al.   Scientific Reports

Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine

(2016) Drew D. Kiraly et al.   Scientific Reports

Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

(2015) Lieve Desbonnet et al.   BRAIN BEHAVIOR AND IMMUNITY

MyD88 Signaling in T Cells Directs IgA-Mediated Control of the Microbiota to Promote Health

(2015) Jason L. Kubinak et al.   Cell Host & Microbe

Control of Brain Development, Function, and Behavior by the Microbiome

(2015) Timothy R. Sampson et al.   Cell Host & Microbe

How informative is the mouse for human gut microbiota research?

(2015) T. L. A. Nguyen et al.   Disease Models & Mechanisms

Adult attachment style is associated with cerebral μ-opioid receptor availability in humans

(2015) Lauri Nummenmaa et al.   HUMAN BRAIN MAPPING

Antibiotic Exposure and the Risk for Depression, Anxiety, or Psychosis

(2015) Ido Lurie et al.   JOURNAL OF CLINICAL PSYCHIATRY

It still hurts: altered endogenous opioid activity in the brain during social rejection and acceptance in major depressive disorder

(2015) D T Hsu et al.   MOLECULAR PSYCHIATRY

Stress and opioids: Role of opioids in modulating stress-related behavior and effect of stress on morphine conditioned place preference

(2015) Anjana Bali et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Same Exposure but Two Radically Different Responses to Antibiotics: Resilience of the Salivary Microbiome versus Long-Term Microbial Shifts in Feces

(2015) E. Zaura et al.   mBio

Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system

(2015) Antonis Koussounadis et al.   Scientific Reports

Lactobacillus fermentumNS9 restores the antibiotic induced physiological and psychological abnormalities in rats

(2015) T. Wang et al.   Beneficial Microbes

Oxytocin regulates gastrointestinal motility, inflammation, macromolecular permeability, and mucosal maintenance in mice

(2014) Martha G. Welch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Antibiotics and the gut microbiota

(2014) Sheetal R. Modi et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamic Interactions Between Plasma IL-1 Family Cytokines and Central Endogenous Opioid Neurotransmitter Function in Humans

(2014) Alan R Prossin et al.   NEUROPSYCHOPHARMACOLOGY

Autistic-Like Syndrome in Mu Opioid Receptor Null Mice is Relieved by Facilitated mGluR4 Activity

(2014) Jérôme AJ Becker et al.   NEUROPSYCHOPHARMACOLOGY

Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats

(2014) S.M. O’Mahony et al.   NEUROSCIENCE

Differential Expressions of the Alternatively Spliced Variant mRNAs of the µ Opioid Receptor Gene, OPRM1, in Brain Regions of Four Inbred Mouse Strains

(2014) Jin Xu et al.   PLoS One

Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats

(2014) Michèle Crumeyrolle-Arias et al.   PSYCHONEUROENDOCRINOLOGY

The neuroanatomical distribution of oxytocin receptor binding and mRNA in the male rhesus macaque (Macaca mulatta)

(2014) Sara M. Freeman et al.   PSYCHONEUROENDOCRINOLOGY

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

State-dependent μ-opioid modulation of social motivation

(2014) Guro E. Loseth et al.   Frontiers in Behavioral Neuroscience

Correction: High-order social interactions in groups of mice

(2014) Yair Shemesh et al.   eLife

Region Specific Up-Regulation of Oxytocin Receptors in the Opioid Oprm1−/− Mouse Model of Autism

(2014) Valentina Gigliucci et al.   Frontiers in Pediatrics

Microbiota signalling through MyD88 is necessary for a systemic neutrophilic inflammatory response

(2013) Dipti Karmarkar et al.   IMMUNOLOGY

Nondigestible oligosaccharides exert nonprebiotic effects on intestinal epithelial cells enhancing the immune response via activation of TLR4-NFκB

(2013) Mercedes Ortega-González et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Microbiota is essential for social development in the mouse

(2013) L Desbonnet et al.   MOLECULAR PSYCHIATRY

Response of the μ-opioid system to social rejection and acceptance

(2013) D T Hsu et al.   MOLECULAR PSYCHIATRY

Innate immune recognition of the microbiota promotes host-microbial symbiosis

(2013) Hiutung Chu et al.   NATURE IMMUNOLOGY

Microbial Symbionts Accelerate Wound Healing via the Neuropeptide Hormone Oxytocin

(2013) Theofilos Poutahidis et al.   PLoS One

Elevated serotonin and 5-HIAA in the brainstem and lower serotonin turnover in the prefrontal cortex of suicides

(2013) Helene Bach et al.   SYNAPSE

The Relative Contribution of Proximal 5′ Flanking Sequence and Microsatellite Variation on Brain Vasopressin 1a Receptor (Avpr1a) Gene Expression and Behavior

(2013) Zoe R. Donaldson et al.   PLoS Genetics

Mu-Opioid Receptors and Dietary Protein Stimulate a Gut-Brain Neural Circuitry Limiting Food Intake

(2012) Celine Duraffourd et al.   CELL

The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

(2012) G Clarke et al.   MOLECULAR PSYCHIATRY

The animal and human neuroendocrinology of social cognition, motivation and behavior

(2012) Cade McCall et al.   NATURE NEUROSCIENCE

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

(2012) Christine Vogel et al.   NATURE REVIEWS GENETICS

The interplay between the intestinal microbiota and the brain

(2012) Stephen M. Collins et al.   NATURE REVIEWS MICROBIOLOGY

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

Trends of Outpatient Prescription Drug Utilization in US Children, 2002-2010

(2012) G. Chai et al.   PEDIATRICS

Vasopressin V1a and V1b Receptors: From Molecules to Physiological Systems

(2012) Taka-aki Koshimizu et al.   PHYSIOLOGICAL REVIEWS

Role of the mu-opioid receptor in opioid modulation of immune function

(2011) Jana Ninković et al.   AMINO ACIDS

Neurotoxic effects associated with antibiotic use: management considerations

(2011) Marie F. Grill et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A MyD88-dependent IFNγR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge

(2011) Eric M Pietras et al.   CELL RESEARCH

The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice

(2011) Premysl Bercik et al.   GASTROENTEROLOGY

Differential Expression and Sensitivity of Presynaptic and Postsynaptic Opioid Receptors Regulating Hypothalamic Proopiomelanocortin Neurons

(2011) R. L. Pennock et al.   JOURNAL OF NEUROSCIENCE

Nucleus Accumbens  -Opioid Receptors Mediate Social Reward

(2011) V. Trezza et al.   JOURNAL OF NEUROSCIENCE

Activation of μ-Opioid Receptors in the Dorsal Striatum is Necessary for Adult Social Attachment in Monogamous Prairie Voles

(2011) James P Burkett et al.   NEUROPSYCHOPHARMACOLOGY

Depletion of Murine Intestinal Microbiota: Effects on Gut Mucosa and Epithelial Gene Expression

(2011) Dag Henrik Reikvam et al.   PLoS One

Normal gut microbiota modulates brain development and behavior

(2011) R. D. Heijtz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenic and Protective Roles of MyD88 in Leukocytes and Epithelial Cells in Mouse Models of Inflammatory Bowel Disease

(2010) Mark J. Asquith et al.   GASTROENTEROLOGY

Phylogeny of Gammaproteobacteria

(2010) K. P. Williams et al.   JOURNAL OF BACTERIOLOGY

Oxytocin-Induced Analgesia and Scratching Are Mediated by the Vasopressin-1A Receptor in the Mouse

(2010) A. Schorscher-Petcu et al.   JOURNAL OF NEUROSCIENCE

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Human mucosal in vivo transcriptome responses to three lactobacilli indicate how probiotics may modulate human cellular pathways

(2010) P. van Baarlen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro

(2009) J.M. Dean et al.   BRAIN BEHAVIOR AND IMMUNITY

The role of β-endorphin in the pathophysiology of major depression

(2009) K.M. Hegadoren et al.   NEUROPEPTIDES

Serotonin targets inhibitory synapses to induce modulation of network functions

(2009) T. Manzke et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Reward Processing by the Opioid System in the Brain

(2009) Julie Le Merrer et al.   PHYSIOLOGICAL REVIEWS

Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior

(2009) S. D. Mague et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential NF- B pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance

(2009) P. van Baarlen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probiotics promote gut health through stimulation of epithelial innate immunity

(2009) C. Pagnini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opioid receptors in the gastrointestinal tract

(2009) Peter Holzer   REGULATORY PEPTIDES

Morphine Desensitization, Internalization, and Down-Regulation of the   Opioid Receptor Is Facilitated by Serotonin 5-Hydroxytryptamine2A Receptor Coactivation

(2008) J. F. Lopez-Gimenez et al.   MOLECULAR PHARMACOLOGY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Oxytocin, Vasopressin, and the Neurogenetics of Sociality

(2008) Z. R. Donaldson et al.   SCIENCE