Moody microbes or fecal phrenology: what do we know about the microbiota-gut-brain axis?

Prebiotic administration normalizes lipopolysaccharide (LPS)-induced anxiety and cortical 5-HT2A receptor and IL1-β levels in male mice

(2016) Helene M. Savignac et al.   BRAIN BEHAVIOR AND IMMUNITY

Magnetic resonance spectroscopy reveals oral Lactobacillus promotion of increases in brain GABA, N-acetyl aspartate and glutamate

(2016) Rafal Janik et al.   NEUROIMAGE

Structural & functional consequences of chronic psychosocial stress on the microbiome & host

(2016) Aadil Bharwani et al.   PSYCHONEUROENDOCRINOLOGY

Obese-type Gut Microbiota Induce Neurobehavioral Changes in the Absence of Obesity

(2015) Annadora J. Bruce-Keller et al.   BIOLOGICAL PSYCHIATRY

The prebiotics 3′Sialyllactose and 6′Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: Evidence for effects on the gut–brain axis

(2015) Andrew J. Tarr et al.   BRAIN BEHAVIOR AND IMMUNITY

Gut microbiome composition is associated with temperament during early childhood

(2015) Lisa M. Christian et al.   BRAIN BEHAVIOR AND IMMUNITY

Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

(2015) Lieve Desbonnet et al.   BRAIN BEHAVIOR AND IMMUNITY

Altered fecal microbiota composition in patients with major depressive disorder

(2015) Haiyin Jiang et al.   BRAIN BEHAVIOR AND IMMUNITY

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

Cognitive Dysfunction in Depression – Pathophysiology and Novel Targets

(2015) Andre Carvalho et al.   CNS & Neurological Disorders-Drug Targets

How informative is the mouse for human gut microbiota research?

(2015) T. L. A. Nguyen et al.   Disease Models & Mechanisms

Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

(2015) Christopher S. Reigstad et al.   FASEB JOURNAL

Gut commensal microvesicles reproduce parent bacterial signals to host immune and enteric nervous systems

(2015) Khalid Al-Nedawi et al.   FASEB JOURNAL

Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates

(2015) Doris Vandeputte et al.   GUT

Gut/brain axis and the microbiota

(2015) Emeran A. Mayer et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of a human milk oligosaccharide, 2′-fucosyllactose, on hippocampal long-term potentiation and learning capabilities in rodents

(2015) Enrique Vázquez et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The TRPV1 channel in rodents is a major target for antinociceptive effect of the probioticLactobacillus reuteriDSM 17938

(2015) Azucena Perez-Burgos et al.   JOURNAL OF PHYSIOLOGY-LONDON

Resistant starches differentially stimulate Toll-like receptors and attenuate proinflammatory cytokines in dendritic cells by modulation of intestinal epithelial cells

(2015) Miriam Bermudez-Brito et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

The gut microbiome restores intrinsic and extrinsic nerve function in germ-free mice accompanied by changes in calbindin

(2015) K. A. McVey Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Microbiota Controls the Homeostasis of Glial Cells in the Gut Lamina Propria

(2015) Panagiotis S. Kabouridis et al.   NEURON

Isovaleric acid in stool correlates with human depression

(2015) Olga Szczesniak et al.   NUTRITIONAL NEUROSCIENCE

Microbiota and host determinants of behavioural phenotype in maternally separated mice

(2015) G. De Palma et al.   Nature Communications

Quorum Sensing Peptides Selectively Penetrate the Blood-Brain Barrier

(2015) Evelien Wynendaele et al.   PLoS One

Comparison of Fecal Microbiota in Children with Autism Spectrum Disorders and Neurotypical Siblings in the Simons Simplex Collection

(2015) Joshua S. Son et al.   PLoS One

Altered brain-gut axis in autism: Comorbidity or causative mechanisms?

(2014) Emeran A. Mayer et al.   BIOESSAYS

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

(2014) Filipe De Vadder et al.   CELL

Tetracyclines in Traumatic Brain Injury and Sepsis

(2014) Marc Maegele   CRITICAL CARE MEDICINE

The gut-brain axis rewired: adding a functional vagal nicotinic “sensory synapse”

(2014) Azucena Perez-Burgos et al.   FASEB JOURNAL

Gut Microbes and the Brain: Paradigm Shift in Neuroscience

(2014) E. A. Mayer et al.   JOURNAL OF NEUROSCIENCE

Correlation between the human fecal microbiota and depression

(2014) A. Naseribafrouei et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats

(2014) S.M. O’Mahony et al.   NEUROSCIENCE

Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity

(2014) Sophie Leclercq et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholinergic neurotransmission links solitary chemosensory cells to nasal inflammation

(2014) C. J. Saunders et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Psychobiotics: A Novel Class of Psychotropic

(2013) Timothy G. Dinan et al.   BIOLOGICAL PSYCHIATRY

Altered gut microbiota and activity in a murine model of autism spectrum disorders

(2013) Caroline G.M. de Theije et al.   BRAIN BEHAVIOR AND IMMUNITY

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Consumption of Fermented Milk Product With Probiotic Modulates Brain Activity

(2013) Kirsten Tillisch et al.   GASTROENTEROLOGY

Complex Interactions Among Diet, Gastrointestinal Transit, and Gut Microbiota in Humanized Mice

(2013) Purna C. Kashyap et al.   GASTROENTEROLOGY

Rifaximin Alters Intestinal Bacteria and Prevents Stress-Induced Gut Inflammation and Visceral Hyperalgesia in Rats

(2013) Dabo Xu et al.   GASTROENTEROLOGY

Stochastic changes over time and not founder effects drive cage effects in microbial community assembly in a mouse model

(2013) Jonathan McCafferty et al.   ISME Journal

Histamine receptor 2 modifies dendritic cell responses to microbial ligands

(2013) Remo Frei et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Intestinal microbiota influence the early postnatal development of the enteric nervous system

(2013) J. Collins et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children

(2013) Dae-Wook Kang et al.   PLoS One

Fucosylated but Not Sialylated Milk Oligosaccharides Diminish Colon Motor Contractions

(2013) John Bienenstock et al.   PLoS One

Effects of Lactobacillus helveticus on murine behavior are dependent on diet and genotype and correlate with alterations in the gut microbiome

(2013) Christina L. Ohland et al.   PSYCHONEUROENDOCRINOLOGY

Bacteroides fragilis polysaccharide A is necessary and sufficient for acute activation of intestinal sensory neurons

(2013) Yu-Kang Mao et al.   Nature Communications

Psychoactive bacteria Lactobacillus rhamnosus (JB-1) elicits rapid frequency facilitation in vagal afferents

(2012) Azucena Perez-Burgos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Molecular Characterisation of Gastrointestinal Microbiota of Children With Autism (With and Without Gastrointestinal Dysfunction) and Their Neurotypical Siblings

(2012) Shakuntla V. Gondalia et al.   Autism Research

Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota

(2012) Hachung Chung et al.   CELL

Voices from within: gut microbes and the CNS

(2012) Paul Forsythe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Elevated Fecal Short Chain Fatty Acid and Ammonia Concentrations in Children with Autism Spectrum Disorder

(2012) Lv Wang et al.   DIGESTIVE DISEASES AND SCIENCES

Brain-Gut Interactions in Inflammatory Bowel Disease

(2012) Bruno L. Bonaz et al.   GASTROENTEROLOGY

Human milk oligosaccharides: Every baby needs a sugar mama

(2012) L. Bode   GLYCOBIOLOGY

Etiology of autistic features: the persisting neurotoxic effects of propionic acid

(2012) Afaf K El-Ansary et al.   Journal of Neuroinflammation

The microbiome is essential for normal gut intrinsic primary afferent neuron excitability in the mouse

(2012) K. A. McVey Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Histamine Derived from Probiotic Lactobacillus reuteri Suppresses TNF via Modulation of PKA and ERK Signaling

(2012) Carissa M. Thomas et al.   PLoS One

Gut Microbiota Composition Is Correlated to Grid Floor Induced Stress and Behavior in the BALB/c Mouse

(2012) Katja Maria Bangsgaard Bendtsen et al.   PLoS One

A Symbiotic View of Life: We Have Never Been Individuals

(2012) Scott F. Gilbert et al.   QUARTERLY REVIEW OF BIOLOGY

Systemic treatment with the enteric bacterial fermentation product, propionic acid, produces both conditioned taste avoidance and conditioned place avoidance in rats

(2011) Klaus-Peter Ossenkopp et al.   BEHAVIOURAL BRAIN RESEARCH

Probiotics function mechanistically as delivery vehicles for neuroactive compounds: Microbial endocrinology in the design and use of probiotics

(2011) Mark Lyte   BIOESSAYS

Probiotic Lactobacillus reuteri Alleviates the Response to Gastric Distension in Rats

(2011) Swantje C. Duncker et al.   JOURNAL OF NUTRITION

Detection and signaling of glucose in the intestinal mucosa - vagal pathway

(2011) L. Ashley Blackshaw et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication

(2011) P. Bercik et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Impaired Carbohydrate Digestion and Transport and Mucosal Dysbiosis in the Intestines of Children with Autism and Gastrointestinal Disturbances

(2011) Brent L. Williams et al.   PLoS One

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)

(2011) I. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal gut microbiota modulates brain development and behavior

(2011) R. D. Heijtz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyrosequencing study of fecal microflora of autistic and control children

(2010) Sydney M. Finegold et al.   ANAEROBE

Exposure to a social stressor alters the structure of the intestinal microbiota: Implications for stressor-induced immunomodulation

(2010) Michael T. Bailey et al.   BRAIN BEHAVIOR AND IMMUNITY

Assessment of psychotropic-like properties of a probiotic formulation ( Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects

(2010) Michaël Messaoudi et al.   BRITISH JOURNAL OF NUTRITION

TRP Channels in the Digestive System

(2010) Peter Holzer   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice

(2010) Premysl Bercik et al.   GASTROENTEROLOGY

Bacterial infection causes stress-induced memory dysfunction in mice

(2010) M. G. Gareau et al.   GUT

Reduced anxiety-like behavior and central neurochemical change in germ-free mice

(2010) K. M. Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression

(2010) L. Desbonnet et al.   NEUROSCIENCE

Sialic Acid Is an Essential Nutrient for Brain Development and Cognition

(2009) Bing Wang   Annual Review of Nutrition

Gastrointestinal microbiology enters the metagenomics era

(2009) Daniel N Frank et al.   CURRENT OPINION IN GASTROENTEROLOGY

Lactobacillus reuterienhances excitability of colonic AH neurons by inhibiting calcium-dependent potassium channel opening

(2009) Wolfgang A. Kunze et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Functional protease-activated receptors in the dorsal motor nucleus of the vagus

(2009) h. wang et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

A randomized, double-blind, placebo-controlled pilot study of a probiotic in emotional symptoms of chronic fatigue syndrome

(2009) A Venket Rao et al.   Gut Pathogens

Significant immunomodulatory effects ofPseudomonas aeruginosaquorum-sensing signal molecules: possible link in human sepsis

(2008) Pisake Boontham et al.   CLINICAL SCIENCE

Inter-kingdom signalling: communication between bacteria and their hosts

(2008) David T. Hughes et al.   NATURE REVIEWS MICROBIOLOGY

Memory and learning behavior in mice is temporally associated with diet-induced alterations in gut bacteria

(2008) Wang Li et al.   PHYSIOLOGY & BEHAVIOR

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial endocrinology: how stress influences susceptibility to infection

(2008) Primrose P.E. Freestone et al.   TRENDS IN MICROBIOLOGY

Minocycline attenuates cognitive impairment and restrains oxidative stress in the hippocampus of rats with chronic cerebral hypoperfusion

(2008) Zhi-You Cai et al.   Neuroscience Bulletin