Silver Nanoparticles Induced Oxidative Stress and Mitochondrial Injuries Mediated Autophagy in HC11 Cells Through Akt/AMPK/mTOR Pathway

Molecular regulation of autophagy machinery by mTOR‐dependent and ‐independent pathways

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Titanium dioxide nanoparticles promote oxidative stress, autophagy and reduce NLRP3 in primary rat astrocytes

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Iron deficiency‐induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria‐containing vesicles

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Role of the autophagy-related marker LC3 expression in hepatocellular carcinoma: a meta-analysis

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Dual role of oxidative stress-JNK activation in autophagy and apoptosis induced by nickel oxide nanoparticles in human cancer cells

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Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells

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Intersections between Regulated Cell Death and Autophagy

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Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death

(2019) Marzena Szwed et al.   Nanotoxicology

Silver nanoparticles induce protective autophagy via Ca2+/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains

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Lysosomal dysfunction is associated with persistent lung injury in dams caused by pregnancy exposure to carbon black nanoparticles

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Mitophagy protects against acetaminophen-induced acute liver injury in mice through inhibiting NLRP3 inflammasome activation

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Biosynthesized silver nanoparticles and their genotoxicity

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Three-dimensional nanoparticle assemblies with tunable plasmonics via a layer-by-layer process

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Nrf2-Keap1 signaling in oxidative and reductive stress

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Weicao capsule ameliorates renal injury through increasing autophagy and NLRP3 degradation in UAN rats

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Silica nanoparticles induce autophagy dysfunction via lysosomal impairment in hepatocytes

(2018) Ji Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Influences of different dietary energy level on sheep testicular development associated with AMPK/ULK1/autophagy pathway

(2018) Jing Pang et al.   THERIOGENOLOGY

Silver nanoparticles induce lysosomal-autophagic defects and decreased expression of transcription factor EB in A549 human lung adenocarcinoma cells

(2018) Takamitsu Miyayama et al.   TOXICOLOGY IN VITRO

A systematic review on silver nanoparticles-induced cytotoxicity: Physicochemical properties and perspectives

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Autophagic effects and mechanisms of silver nanoparticles in renal cells under low dose exposure

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ATM signals to AMPK to promote autophagy and positively regulate DNA damage in response to cadmium-induced ROS in mouse spermatocytes

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The Role of Reactive Oxygen Species (ROS) in the Biological Activities of Metallic Nanoparticles

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Involvement of PINK1/parkin-mediated mitophagy in ZnO nanoparticle-induced toxicity in BV-2 cells

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Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis

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Nano-TiO2 induces autophagy to protect against cell death through antioxidative mechanism in podocytes

(2016) Xiaochen Zhang et al.   CELL BIOLOGY AND TOXICOLOGY

Silver nanoparticles synthesized from Adenium obesum leaf extract induced DNA damage, apoptosis and autophagy via generation of reactive oxygen species

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Akt/AMPK/mTOR pathway was involved in the autophagy induced by vitamin E succinate in human gastric cancer SGC-7901 cells

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Low-dose, subchronic exposure to silver nanoparticles causes mitochondrial alterations in Sprague–Dawley rats

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Comparative oxidative stress elicited by nanosilver in stable HSPA1A promoter-driven luciferase reporter HepG2 and A549 cells

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A systematic review of evidence for silver nanoparticle-induced mitochondrial toxicity

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Therapeutic Targeting of Autophagy

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Silver nanoparticles activate endoplasmic reticulum stress signaling pathway in cell and mouse models: The role in toxicity evaluation

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Oxidative stress and mitochondrial injury-mediated cytotoxicity induced by silver nanoparticles in human A549 and HepG2 cells

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Silver Nanoparticle Exposure Induced Mitochondrial Stress, Caspase-3 Activation and Cell Death: Amelioration by Sodium Selenite

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Differential nanoreprotoxicity of silver nanoparticles in male somatic cells and spermatogonial stem cells

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Silver Nanoparticles Induce Degradation of the Endoplasmic Reticulum Stress Sensor Activating Transcription Factor-6 Leading to Activation of the NLRP-3 Inflammasome

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Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy

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Silver nanoparticles impede phorbol myristate acetate-induced monocyte–macrophage differentiation and autophagy

(2015) Yingying Xu et al.   Nanoscale

Differential Regulation of Gene and Protein Expression by Zinc Oxide Nanoparticles in Hen’s Ovarian Granulosa Cells: Specific Roles of Nanoparticles

(2015) Yong Zhao et al.   PLoS One

Interference in Autophagosome Fusion by Rare Earth Nanoparticles Disrupts Autophagic Flux and Regulation of an Interleukin-1β Producing Inflammasome

(2014) Ruibin Li et al.   ACS Nano

Cytotoxicity, oxidative stress, apoptosis and the autophagic effects of silver nanoparticles in mouse embryonic fibroblasts

(2014) Yu-Hsuan Lee et al.   BIOMATERIALS

Induction of cyto-protective autophagy by paramontroseite VO2nanocrystals

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Bioenergetic failure correlates with autophagy and apoptosis in rat liver following silver nanoparticle intraperitoneal administration

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The NAD ratio redox paradox: why does too much reductive power cause oxidative stress?

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Autophagy in the Cellular Energetic Balance

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A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt–TSC2-mTOR signaling

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Autophagosome Formation and Molecular Mechanism of Autophagy

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mTOR regulation of autophagy

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