Molecular mechanism of Fast Endophilin-Mediated Endocytosis

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

(2020) Hui Yi Chew et al.   CELL

Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin

(2020) Sindhuja Gowrisankaran et al.   Nature Communications

Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166

(2020) Henri-François Renard et al.   Nature Communications

Glycosylation and glycan interactions can serve as extracellular machinery facilitating clathrin‐independent endocytosis

(2019) Mohit P. Mathew et al.   TRAFFIC

Endophilin 1 knockdown prevents synaptic dysfunction induced by oligomeric amyloid β

(2019) Yichen Yin et al.   Molecular Medicine Reports

Spoiled for Choice: Diverse Endocytic Pathways Function at the Cell Surface

(2019) Joseph Jose Thottacherry et al.   Annual Review of Cell and Developmental Biology

On the existence of endocytosis driven by membrane phase separations

(2019) Donald W. Hilgemann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Structural Biology of the Dynamin‐Related Proteins: New Insights into a Diverse, Multi‐Talented Family

(2019) Marijn G.J. Ford et al.   TRAFFIC

Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis

(2019) Gael Genet et al.   Nature Communications

Local actin polymerization during endocytic carrier formation

(2018) Claudia Hinze et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The dynamin superfamily

(2018) Rajesh Ramachandran et al.   CURRENT BIOLOGY

Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis

(2018) Kumud R. Poudel et al.   DEVELOPMENTAL CELL

Clathrin-independent endocytosis: an increasing degree of complexity

(2018) Kirsten Sandvig et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Inhibition of SHIP2 activity inhibits cell migration and could prevent metastasis in breast cancer cells

(2018) Somadri Ghosh et al.   JOURNAL OF CELL SCIENCE

High expression of FBP17 in invasive breast cancer cells promotes invadopodia formation

(2018) Prabhat Suman et al.   MEDICAL ONCOLOGY

Mechanisms of clathrin-mediated endocytosis

(2018) Marko Kaksonen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Synaptojanin and Endophilin Mediate Neck Formation during Ultrafast Endocytosis

(2018) Shigeki Watanabe et al.   NEURON

Mechanisms of Carrier Formation during Clathrin-Independent Endocytosis

(2018) Antonio P.A. Ferreira et al.   TRENDS IN CELL BIOLOGY

Quantitative and Statistical Study of the Dynamics of Clathrin-Dependent and -Independent Endocytosis Reveal a Differential Role of EndophilinA2

(2018) Laetitia Bertot et al.   Cell Reports

FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis

(2018) Laura Chan Wah Hak et al.   NATURE CELL BIOLOGY

To degrade or not to degrade: mechanisms and significance of endocytic recycling

(2018) Peter J. Cullen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease

(2018) Qing Yu et al.   Nature Communications

Caveolae: Structure, Function, and Relationship to Disease

(2018) Robert G. Parton   Annual Review of Cell and Developmental Biology

A high-avidity biosensor reveals plasma membrane PI(3,4)P2 is predominantly a class I PI3K signaling product

(2018) Brady D. Goulden et al.   JOURNAL OF CELL BIOLOGY

Dorsal ruffles enhance activation of Akt by growth factors

(2018) Sei Yoshida et al.   JOURNAL OF CELL SCIENCE

PTEN Regulates PI(3,4)P 2 Signaling Downstream of Class I PI3K

(2017) Mouhannad Malek et al.   MOLECULAR CELL

Reticulon 3–dependent ER-PM contact sites control EGFR nonclathrin endocytosis

(2017) Giusi Caldieri et al.   SCIENCE

Chemical inhibitors of Candida albicans hyphal morphogenesis target endocytosis

(2017) Hagit Bar-Yosef et al.   Scientific Reports

Coordinated Movement of Vesicles and Actin Bundles during Nerve Growth Revealed by Superresolution Microscopy

(2017) Motohiro Nozumi et al.   Cell Reports

Shiga Toxin—A Model for Glycolipid-Dependent and Lectin-Driven Endocytosis

(2017) Ludger Johannes   Toxins

Structural inhibition of dynamin-mediated membrane fission by endophilin

(2017) Annika Hohendahl et al.   eLife

Endophilin2 Interacts with GluA1 to Mediate AMPA Receptor Endocytosis Induced by Oligomeric Amyloid-β

(2017) Jifeng Zhang et al.   NEURAL PLASTICITY

Endophilin-A2-mediated increase in scavenger receptor expression contributes to macrophage-derived foam cell formation

(2016) Er-Wen Huang et al.   ATHEROSCLEROSIS

Endophilin A2 Influences Volume-Regulated Chloride Current by Mediating ClC-3 Trafficking in Vascular Smooth Muscle Cells

(2016) Can-Zhao Liu et al.   CIRCULATION JOURNAL

Bridging Integrator 1 (BIN1) Genotypes Mediate Alzheimer’s Disease Risk by Altering Neuronal Degeneration

(2016) Hui-Fu Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Glycolipids and Lectins in Endocytic Uptake Processes

(2016) Ludger Johannes et al.   JOURNAL OF MOLECULAR BIOLOGY

β-Arrestin drives MAP kinase signalling from clathrin-coated structures after GPCR dissociation

(2016) K. Eichel et al.   NATURE CELL BIOLOGY

Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE

(2016) G Carmona et al.   ONCOGENE

SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway

(2016) Yiming Tao et al.   Oncotarget

Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System

(2016) John D. Murdoch et al.   Cell Reports

Loss of Bin1 Promotes the Propagation of Tau Pathology

(2016) Sara Calafate et al.   Cell Reports

ALG-2 interacting protein-X (Alix) is essential for clathrin-independent endocytosis and signaling

(2016) Vincent Mercier et al.   Scientific Reports

Are caveolae a cellular entry route for non-viral therapeutic delivery systems?

(2015) Prarthana V. Rewatkar et al.   ADVANCED DRUG DELIVERY REVIEWS

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

(2015) Marco Y. Hein et al.   CELL

Membrane protrusion powers clathrin-independent endocytosis of interleukin-2 receptor

(2015) C. Basquin et al.   EMBO JOURNAL

Crosstalk between Akt/GSK3  signaling and dynamin-1 regulates clathrin-mediated endocytosis

(2015) C. R. Reis et al.   EMBO JOURNAL

Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models

(2015) Mario Schiffer et al.   NATURE MEDICINE

Microtubule Motors Power Plasma Membrane Tubulation in Clathrin-Independent Endocytosis

(2015) Charles A. Day et al.   TRAFFIC

Phenothiazine-Derived Antipsychotic Drugs Inhibit Dynamin and Clathrin-Mediated Endocytosis

(2015) James A. Daniel et al.   TRAFFIC

CIP4 promotes metastasis in triple-negative breast cancer and is associated with poor patient prognosis

(2015) Otto L.D. Cerqueira et al.   Oncotarget

NK cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy

(2015) Wei Wang   Frontiers in Immunology

Loss of Sh3gl2/Endophilin A1 Is a Common Event in Urothelial Carcinoma that Promotes Malignant Behavior

(2015) Shyama Majumdar et al.   NEOPLASIA

Evidence for the Interaction of Endophilin A3 with Endogenous Kca2.3 Channels in PC12 Cells

(2014) Malika Janbein et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Vesicle uncoating regulated by SH3-SH3 domain-mediated complex formation between endophilin and intersectin at synapses

(2014) A. Pechstein et al.   EMBO REPORTS

LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism

(2014) A. M. Arranz et al.   JOURNAL OF CELL SCIENCE

Repurposing of Prochlorperazine for Use Against Dengue Virus Infection

(2014) Yogy Simanjuntak et al.   JOURNAL OF INFECTIOUS DISEASES

Intradimer/Intermolecular Interactions Suggest Autoinhibition Mechanism in Endophilin A1

(2014) Zhiming Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis

(2014) Henri-François Renard et al.   NATURE

Endophilin marks and controls a clathrin-independent endocytic pathway

(2014) Emmanuel Boucrot et al.   NATURE

Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers

(2014) Ramya Lakshminarayan et al.   NATURE CELL BIOLOGY

CIP4 promotes lung adenocarcinoma metastasis and is associated with poor prognosis

(2014) P Truesdell et al.   ONCOGENE

Endophilin A1 induces different membrane shapes using a conformational switch that is regulated by phosphorylation

(2014) M. R. Ambroso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyunsaturated phospholipids facilitate membrane deformation and fission by endocytic proteins

(2014) M. Pinot et al.   SCIENCE

Endosome maturation, transport and functions

(2014) Cameron C. Scott et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Upregulated dynamin 1 in an acute seizure model and in epileptic patients

(2014) Ying-Ying Li et al.   SYNAPSE

Clathrin-Independent Pathways of Endocytosis

(2014) S. Mayor et al.   Cold Spring Harbor Perspectives in Biology

Clathrin-independent pathways do not contribute significantly to endocytic flux

(2014) Vassilis Bitsikas et al.   eLife

Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis

(2013) Anne Vehlow et al.   EMBO JOURNAL

Clathrin-independent endocytosis: A cargo-centric view

(2013) Lymarie Maldonado-Báez et al.   EXPERIMENTAL CELL RESEARCH

Cooperative Recruitment of Dynamin and BIN/Amphiphysin/Rvs (BAR) Domain-containing Proteins Leads to GTP-dependent Membrane Scission

(2013) Michael Meinecke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Virus entry at a glance

(2013) Y. Yamauchi et al.   JOURNAL OF CELL SCIENCE

The signalling factor PI3K is a specific regulator of the clathrin-independent dynamin-dependent endocytosis of IL-2 receptors

(2013) C. Basquin et al.   JOURNAL OF CELL SCIENCE

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

(2013) J Chapuis et al.   MOLECULAR PSYCHIATRY

Ultrafast endocytosis at mouse hippocampal synapses

(2013) Shigeki Watanabe et al.   NATURE

Building a Better Dynasore: The Dyngo Compounds Potently Inhibit Dynamin and Endocytosis

(2013) Adam McCluskey et al.   TRAFFIC

Mouse cytomegalovirus egress protein pM50 interacts with cellular endophilin-A2

(2012) Frederic Lemnitzer et al.   CELLULAR MICROBIOLOGY

LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis

(2012) Samer Matta et al.   NEURON

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recruitment of Endophilin to Clathrin-Coated Pit Necks Is Required for Efficient Vesicle Uncoating after Fission

(2011) Ira Milosevic et al.   NEURON

Interplay between VGLUT Isoforms and Endophilin A1 Regulates Neurotransmitter Release and Short-Term Plasticity

(2011) Matthew C. Weston et al.   NEURON

A High Precision Survey of the Molecular Dynamics of Mammalian Clathrin-Mediated Endocytosis

(2011) Marcus J. Taylor et al.   PLOS BIOLOGY

Endophilin Functions as a Membrane-Bending Molecule and Is Delivered to Endocytic Zones by Exocytosis

(2010) Jihong Bai et al.   CELL

The Structure and Function of Endophilin Proteins

(2010) Ole Kjaerulff et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

(2010) Mirkka Koivusalo et al.   JOURNAL OF CELL BIOLOGY

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

(2010) Mark T. Howes et al.   JOURNAL OF CELL BIOLOGY

An endophilin-dynamin complex promotes budding of clathrin-coated vesicles during synaptic vesicle recycling

(2010) A. Sundborger et al.   JOURNAL OF CELL SCIENCE

Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles

(2010) Emma L Clayton et al.   NATURE NEUROSCIENCE

Roles of AP-2 in Clathrin-Mediated Endocytosis

(2010) Emmanuel Boucrot et al.   PLoS One

Evidence that Inositol Polyphosphate 4-Phosphatase Type II Is a Tumor Suppressor that Inhibits PI3K Signaling

(2009) Christina Gewinner et al.   CANCER CELL

A Phosphoinositide Switch Controls the Maturation and Signaling Properties of APPL Endosomes

(2009) Roberto Zoncu et al.   CELL

Inhibition of Dynamin Mediated Endocytosis by theDynoles—Synthesis and Functional Activity of a Family of Indoles

(2009) Timothy A. Hill et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dynamin- and Clathrin-Dependent Endocytosis in African Swine Fever Virus Entry

(2009) B. Hernaez et al.   JOURNAL OF VIROLOGY

Cargo and Dynamin Regulate Clathrin-Coated Pit Maturation

(2009) Dinah Loerke et al.   PLOS BIOLOGY

Structure of the SH3 domain of rat endophilin A2

(2008) Patrick J. Loll et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

The GTPase-Activating Protein GRAF1 Regulates the CLIC/GEEC Endocytic Pathway

(2008) Richard Lundmark et al.   CURRENT BIOLOGY

Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation

(2008) Sara Sigismund et al.   DEVELOPMENTAL CELL

Clathrin-independent endocytosis used by the IL-2 receptor is regulated by Rac1, Pak1 and Pak2

(2008) Alexandre Grassart et al.   EMBO REPORTS

Constitutive Internalization of G Protein-coupled Receptors and G Proteins via Clathrin-independent Endocytosis

(2008) Marco Scarselli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bulk Synaptic Vesicle Endocytosis Is Rapidly Triggered during Strong Stimulation

(2008) E. L. Clayton et al.   JOURNAL OF NEUROSCIENCE