Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE

Open source software for quantification of cell migration, protrusions, and fluorescence intensities

(2015) David J. Barry et al.   JOURNAL OF CELL BIOLOGY

Digging a little deeper: The stages of invadopodium formation and maturation

(2014) Brian T. Beaty et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Mutant p53–associated myosin-X upregulation promotes breast cancer invasion and metastasis

(2014) Antti Arjonen et al.   JOURNAL OF CLINICAL INVESTIGATION

Steering cell migration: lamellipodium dynamics and the regulation of directional persistence

(2014) Matthias Krause et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tks5 and SHIP2 Regulate Invadopodium Maturation, but Not Initiation, in Breast Carcinoma Cells

(2013) Ved P. Sharma et al.   CURRENT BIOLOGY

Membrane and actin dynamics interplay at lamellipodia leading edge

(2013) Sara Bisi et al.   CURRENT OPINION IN CELL BIOLOGY

Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis

(2013) Anne Vehlow et al.   EMBO JOURNAL

Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo

(2013) Ah-Lai Law et al.   JOURNAL OF CELL BIOLOGY

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors

(2012) B. Gligorijevic et al.   JOURNAL OF CELL SCIENCE

The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain

(2012) J. M. Lamar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Life at the Leading Edge

(2011) Anne J. Ridley   CELL

Molecular mechanism of Ena/VASP-mediated actin-filament elongation

(2011) Dennis Breitsprecher et al.   EMBO JOURNAL

Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer

(2011) E. T. Roussos et al.   JOURNAL OF CELL SCIENCE

c-Abl, Lamellipodin, and Ena/VASP Proteins Cooperate in Dorsal Ruffling of Fibroblasts and Axonal Morphogenesis

(2010) Magdalene Michael et al.   CURRENT BIOLOGY

VASP is a processive actin polymerase that requires monomeric actin for barbed end association

(2010) Scott D. Hansen et al.   JOURNAL OF CELL BIOLOGY

Actin Dynamics at the Leading Edge: From Simple Machinery to Complex Networks

(2009) Robert H. Insall et al.   DEVELOPMENTAL CELL

Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts

(2009) W. D. Bradley et al.   JOURNAL OF CELL SCIENCE

Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia

(2009) R. Poincloux et al.   JOURNAL OF CELL SCIENCE

Src kinases as therapeutic targets for cancer

(2009) Lori C. Kim et al.   Nature Reviews Clinical Oncology

Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model

(2009) S. L. C. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Wave complex is intrinsically inactive

(2009) Emmanuel Derivery et al.   CELL MOTILITY AND THE CYTOSKELETON

Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen

(2008) Sherene Loi et al.   BMC GENOMICS

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Navigating through models of chemotaxis

(2008) Pablo A Iglesias et al.   CURRENT OPINION IN CELL BIOLOGY

Drosophila Pico and Its Mammalian Ortholog Lamellipodin Activate Serum Response Factor and Promote Cell Proliferation

(2008) Ekaterina Lyulcheva et al.   DEVELOPMENTAL CELL

A Mena Invasion Isoform Potentiates EGF-Induced Carcinoma Cell Invasion and Metastasis

(2008) Ulrike Philippar et al.   DEVELOPMENTAL CELL

Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation

(2008) Dennis Breitsprecher et al.   EMBO JOURNAL

Directional sensing during chemotaxis

(2008) Christopher Janetopoulos et al.   FEBS LETTERS

Ena/VASP Proteins Capture Actin Filament Barbed Ends

(2008) Lejla Pasic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY