Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice

Effect of protocatechuic acid on insulin responsiveness and inflammation in visceral adipose tissue from obese individuals: possible role for PTP1B

(2018) Paulina Ormazabal et al.   INTERNATIONAL JOURNAL OF OBESITY

Protective effects of sarsasapogenin against early stage of diabetic nephropathy in rats

(2018) Yao-Wu Liu et al.   PHYTOTHERAPY RESEARCH

Macrophage-Targeted Therapeutics for Metabolic Disease

(2018) Kristin R. Peterson et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue

(2018) Lingyan Wu et al.   Frontiers in Physiology

One-Week Exposure to a Free-Choice High-Fat High-Sugar Diet Does Not Interfere With the Lipopolysaccharide-Induced Acute Phase Response in the Hypothalamus of Male Rats

(2018) Evita Belegri et al.   Frontiers in Endocrinology

MicroRNA-92a antagonism attenuates lipopolysaccharide (LPS)-induced pulmonary inflammation and injury in mice through suppressing the PTEN/AKT/NF-κB signaling pathway

(2018) Liming Fu et al.   BIOMEDICINE & PHARMACOTHERAPY

Inflammation Markers in Type 2 Diabetes and the Metabolic Syndrome in the Pediatric Population

(2018) Thomas Reinehr et al.   Current Diabetes Reports

Foundations of Immunometabolism and Implications for Metabolic Health and Disease

(2017) Gökhan S. Hotamisligil   IMMUNITY

Inflammatory mechanisms linking obesity and metabolic disease

(2017) Alan R. Saltiel et al.   JOURNAL OF CLINICAL INVESTIGATION

Nobiletin Attenuates the Inflammatory Response Through Heme Oxygenase-1 Induction in the Crosstalk Between Adipocytes and Macrophages

(2017) Seulgi Namkoong et al.   JOURNAL OF MEDICINAL FOOD

Inhibitory Effect of Methyl 2-(4′-Methoxy-4′-oxobutanamide) Benzoate from Jerusalem Artichoke (Helianthus tuberosus) on the Inflammatory Paracrine Loop between Macrophages and Adipocytes

(2016) Yun Joo Jung et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Riboflavin Reduces Pro-Inflammatory Activation of Adipocyte-Macrophage Co-culture. Potential Application of Vitamin B2 Enrichment for Attenuation of Insulin Resistance and Metabolic Syndrome Development

(2016) Agnieszka Mazur-Bialy et al.   MOLECULES

Linking Gut Microbiota and Inflammation to Obesity and Insulin Resistance

(2016) M. J. A. Saad et al.   PHYSIOLOGY

Identification of “sarsasapogenin-aglyconed” timosaponins as novel Aβ-lowering modulators of amyloid precursor protein processing

(2016) Lai-King Sy et al.   Chemical Science

Timosaponin AIII and its metabolite sarsasapogenin ameliorate colitis in mice by inhibiting NF-κB and MAPK activation and restoring Th17/Treg cell balance

(2015) Su-Min Lim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Regulation of metabolism by the innate immune system

(2015) Denise E. Lackey et al.   Nature Reviews Endocrinology

Adipokines, diabetes and atherosclerosis: an inflammatory association

(2015) Leandro C. Freitas Lima et al.   Frontiers in Physiology

Implication of the Tpl2 Kinase in Inflammatory Changes and Insulin Resistance Induced by the Interaction Between Adipocytes and Macrophages

(2014) Franck Ceppo et al.   ENDOCRINOLOGY

Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease

(2014) Un Jung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Origins and Drivers of Insulin Resistance

(2013) Andrew M.F. Johnson et al.   CELL

Omega-3 Fatty Acids Reduce Adipose Tissue Macrophages in Human Subjects With Insulin Resistance

(2013) M. Spencer et al.   DIABETES

Reduced Adipose Tissue Macrophage Content Is Associated With Improved Insulin Sensitivity in Thiazolidinedione-Treated Diabetic Humans

(2013) S. Koppaka et al.   DIABETES

Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus

(2013) Andrew E. Hogan et al.   DIABETOLOGIA

Mechanisms of Inflammatory Responses in Obese Adipose Tissue

(2012) Shengyi Sun et al.   Annual Review of Nutrition

Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes

(2012) Y.-S. Lee et al.   DIABETOLOGIA

Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes

(2011) Misaki Iwashita et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states

(2011) David L Morris et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Clodronate Liposomes Improve Metabolic Profile and Reduce Visceral Adipose Macrophage Content in Diet-Induced Obese Mice

(2011) Bin Feng et al.   PLoS One

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Role of CREB in the regulatory action of sarsasapogenin on muscarinic M1receptor density during cell aging

(2010) Haiyan Hu et al.   FEBS LETTERS

Adipose tissue as an endocrine organ

(2009) Sandra Galic et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Steroids from the Roots ofAsparagus officinalisand Their Cytotoxic Activity

(2008) Xue-Feng Huang et al.   Journal of Integrative Plant Biology

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

(2008) Adilson Guilherme et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY