The KBTBD6/7-DRD2 axis regulates pituitary adenoma sensitivity to dopamine agonist treatment

DEPTOR inhibits cell proliferation and confers sensitivity to dopamine agonist in pituitary adenoma

(2019) Hong Yao et al.   CANCER LETTERS

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

(2018) Jia Yu et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-21 prevents excessive inflammation and cardiac dysfunction after myocardial infarction through targeting KBTBD7

(2018) Linshan Yang et al.   Cell Death & Disease

Impaired recruitment of dopamine neurons during working memory in mice with striatal D2 receptor overexpression

(2018) Sevil Duvarci et al.   Nature Communications

Overexpression of striatal D2 receptors reduces motivation thereby decreasing food anticipatory activity

(2018) Joseph LeSauter et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours

(2018) Ze Rui Wu et al.   Nature Communications

Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription

(2017) Amod Godbole et al.   Nature Communications

The DNA Damage Transducer RNF8 Facilitates Cancer Chemoresistance and Progression through Twist Activation

(2016) Hong-Jen Lee et al.   MOLECULAR CELL

Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma

(2016) Philippe Moreau et al.   NEW ENGLAND JOURNAL OF MEDICINE

Daratumumab, Bortezomib, and Dexamethasone for Multiple Myeloma

(2016) Antonio Palumbo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice

(2016) Zhao Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level

(2016) Alina Tabor et al.   Scientific Reports

Inhibition of IRAK1/4 sensitizes T cell acute lymphoblastic leukemia to chemotherapies

(2015) Zhaoyang Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Circadian Clock Gene CRY2 Degradation Is Involved in Chemoresistance of Colorectal Cancer

(2015) L. Fang et al.   MOLECULAR CANCER THERAPEUTICS

CUL3-KBTBD6/KBTBD7 Ubiquitin Ligase Cooperates with GABARAP Proteins to Spatially Restrict TIAM1-RAC1 Signaling

(2015) Heide Marika Genau et al.   MOLECULAR CELL

Upregulation of Dopamine D2 Receptors in the Nucleus Accumbens Indirect Pathway Increases Locomotion but Does Not Reduce Alcohol Consumption

(2015) Eduardo F Gallo et al.   NEUROPSYCHOPHARMACOLOGY

Ubiquitylation of Autophagy Receptor Optineurin by HACE1 Activates Selective Autophagy for Tumor Suppression

(2014) Zhengzhao Liu et al.   CANCER CELL

Preincubation of Pituitary Tumor Cells With the Epidrugs Zebularine and Trichostatin A Are Permissive for Retinoic Acid-Augmented Expression of theBMP-4andD2RGenes

(2013) Kiren Yacqub-Usman et al.   ENDOCRINOLOGY

Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline

(2013) Richard S. Legro et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Dopamine receptor D2S gene transfer improves the sensitivity of GH3 rat pituitary adenoma cells to bromocriptine

(2013) Qiang Li et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Identifying the Ubiquitin Ligase Complex That Regulates the NF1 Tumor Suppressor and Ras

(2013) P. E. Hollstein et al.   Cancer Discovery

Somatostatin receptor sst2 gene transfer in human prolactinomas in vitro: Impact on sensitivity to dopamine, somatostatin and dopastatin, in the control of prolactin secretion

(2012) Thomas Cuny et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1

(2011) Junjian Hu et al.   BMB Reports

Dopamine D2 Receptor Overexpression Alters Behavior and Physiology in Drd2-EGFP Mice

(2011) P. F. Kramer et al.   JOURNAL OF NEUROSCIENCE

Medical treatment of prolactinomas

(2011) Annamaria Colao et al.   Nature Reviews Endocrinology

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

(2011) J.-M. Beaulieu et al.   PHARMACOLOGICAL REVIEWS

KLHL12-mediated ubiquitination of the dopamine D4 receptor does not target the receptor for degradation

(2010) Pieter Rondou et al.   CELLULAR SIGNALLING

Reversal of Endogenous Dopamine Receptor Silencing in Pituitary Cells Augments Receptor-Mediated Apoptosis

(2010) Haneen Al-Azzawi et al.   ENDOCRINOLOGY

Expression of D2RmRNA isoforms and ERmRNA isoforms in prolactinomas: correlation with the response to bromocriptine and with tumor biological behavior

(2010) Zhe Bao Wu et al.   JOURNAL OF NEURO-ONCOLOGY

Contribution of Dopamine D1 and D2 Receptors to Amygdala Activity in Human

(2010) H. Takahashi et al.   JOURNAL OF NEUROSCIENCE

New TFII-I family target genes involved in embryonic development

(2009) Aleksandr V. Makeyev et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting the ubiquitin system in cancer therapy

(2009) Daniela Hoeller et al.   NATURE

Chemotherapy induces NEDP1-mediated destabilization of MDM2

(2009) I R Watson et al.   ONCOGENE

Effect of 9-cis Retinoic Acid on Dopamine D2 Receptor Expression in Pituitary Adenoma Cells

(2008) Sara Bondioni et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

BTB Protein KLHL12 Targets the Dopamine D4 Receptor for Ubiquitination by a Cul3-based E3 Ligase

(2008) Pieter Rondou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Single Mutation at Lysine 241 Alters Expression and Trafficking of the D2Dopamine Receptor

(2008) Ok-Jin Kim   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Genes Differentially Expressed in Prolactinomas Responsive and Resistant to Dopamine Agonists

(2008) Vanessa Q. Passos et al.   NEUROENDOCRINOLOGY