Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance

Characterization of the Blood–Brain Barrier Integrity and the Brain Transport of SN-38 in an Orthotopic Xenograft Rat Model of Diffuse Intrinsic Pontine Glioma

(2020) Catarina Chaves et al.   Pharmaceutics

Established and Emerging Strategies for Drug Delivery Across the Blood-Brain Barrier in Brain Cancer

(2019) Alessandro Parodi et al.   Pharmaceutics

Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand?

(2019) Fatma E. El-Khouly et al.   JOURNAL OF NEURO-ONCOLOGY

ABC Transporters at the Blood–Brain Interfaces, Their Study Models, and Drug Delivery Implications in Gliomas

(2019) David Gomez-Zepeda et al.   Pharmaceutics

Beyond the Blood:Brain Barrier: The Importance of Central Nervous System (CNS) Pharmacokinetics for the Treatment of CNS Tumors, Including Diffuse Intrinsic Pontine Glioma

(2018) Katherine Elizabeth Warren   Frontiers in Oncology

Blood-Brain Barrier: From Physiology to Disease and Back

(2018) Melanie D. Sweeney et al.   PHYSIOLOGICAL REVIEWS

Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models

(2017) Tammy Hennika et al.   PLoS One

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Pathophysiological implications of neurovascular P450 in brain disorders

(2016) Chaitali Ghosh et al.   DRUG DISCOVERY TODAY

Diffuse Intrinsic Pontine Glioma

(2016) Tammy Hennika et al.   JOURNAL OF CHILD NEUROLOGY

Pericytes of the neurovascular unit: key functions and signaling pathways

(2016) Melanie D Sweeney et al.   NATURE NEUROSCIENCE

Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines

(2016) Aurore Drolez et al.   PLoS One

Brain and Retinal Pericytes: Origin, Function and Role

(2016) Andrea Trost et al.   Frontiers in Cellular Neuroscience

Transport of treosulfan and temozolomide across an in-vitro blood–brain barrier model

(2015) Ute Linz et al.   ANTI-CANCER DRUGS

Overcoming the blood–brain tumor barrier for effective glioblastoma treatment

(2015) O. van Tellingen et al.   DRUG RESISTANCE UPDATES

Tumor location, but not H3.3K27M, significantly influences the blood–brain-barrier permeability in a genetic mouse model of pediatric high-grade glioma

(2015) Ergys Subashi et al.   JOURNAL OF NEURO-ONCOLOGY

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

(2015) Catherine S Grasso et al.   NATURE MEDICINE

3D in vitro modeling of the central nervous system

(2015) Amy M. Hopkins et al.   PROGRESS IN NEUROBIOLOGY

Molecular Biology in Pediatric High-Grade Glioma: Impact on Prognosis and Treatment

(2015) Daniela Rizzo et al.   Biomed Research International

Pre-Clinical Models of Diffuse Intrinsic Pontine Glioma

(2015) Katherine L. Misuraca et al.   Frontiers in Oncology

Activation of latent HIV by the histone deacetylase inhibitor panobinostat: A pilot study to assess effects on the CNS

(2015) T. A. Rasmussen et al.   Open Forum Infectious Diseases

A High-Throughput In Vitro Drug Screen in a Genetically Engineered Mouse Model of Diffuse Intrinsic Pontine Glioma Identifies BMS-754807 as a Promising Therapeutic Agent

(2015) Kyle G. Halvorson et al.   PLoS One

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

(2014) Kathryn R Taylor et al.   NATURE GENETICS

A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells

(2014) Romeo Cecchelli et al.   PLoS One

Temozolomide down-regulates P-glycoprotein in human blood–brain barrier cells by disrupting Wnt3 signaling

(2013) Chiara Riganti et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Blood–brain barrier structure and function and the challenges for CNS drug delivery

(2013) N. Joan Abbott   JOURNAL OF INHERITED METABOLIC DISEASE

Children are not just little adults: recent advances in understanding of diffuse intrinsic pontine glioma biology

(2013) Kristin M. Schroeder et al.   PEDIATRIC RESEARCH

In Vitro Drug Response and Efflux Transporters Associated with Drug Resistance in Pediatric High Grade Glioma and Diffuse Intrinsic Pontine Glioma

(2013) Susanna J. E. Veringa et al.   PLoS One

Interplay of Drug Metabolizing CYP450 Enzymes and ABC Transporters in the Blood-Brain Barrier

(2011) Xavier Decleves et al.   CURRENT DRUG METABOLISM

Improved Survival, Vascular Differentiation and Wound Healing Potential of Stem Cells Co-Cultured with Endothelial Cells

(2011) Dora C. S. Pedroso et al.   PLoS One

Peripheral nerve pericytes modify the blood-nerve barrier function and tight junctional molecules through the secretion of various soluble factors

(2010) Fumitaka Shimizu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Integrated Molecular Genetic Profiling of Pediatric High-Grade Gliomas Reveals Key Differences With the Adult Disease

(2010) Barbara S. Paugh et al.   JOURNAL OF CLINICAL ONCOLOGY

Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport

(2008) S. Syvanen et al.   DRUG METABOLISM AND DISPOSITION

Peripheral Nerve pericytes originating from the blood-nerve barrier expresses tight junctional molecules and transporters as barrier-forming cells

(2008) Fumitaka Shimizu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Xenobiotic metabolizing enzymes in the central nervous system: Contribution of cytochrome P450 enzymes in normal and pathological human brain

(2007) Fabien Dutheil et al.   BIOCHIMIE