Choroid plexus and the blood–cerebrospinal fluid barrier in disease

Subarachnoid Hemorrhage Induces Dynamic Immune Cell Reactions in the Choroid Plexus

(2020) Peter Solár et al.   Frontiers in Cellular Neuroscience

JC virus infection of meningeal and choroid plexus cells in patients with progressive multifocal leukoencephalopathy

(2019) Sarah M. Corbridge et al.   JOURNAL OF NEUROVIROLOGY

c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism

(2019) Ashirwad Merve et al.   Acta Neuropathologica Communications

Association of Choroid Plexus Enlargement With Cognitive, Inflammatory, and Structural Phenotypes Across the Psychosis Spectrum

(2019) Paulo Lizano et al.   AMERICAN JOURNAL OF PSYCHIATRY

First Demonstration Water-Filled Vesicles of Choroid Plexus Tumors

(2019) Mehmet Dumlu Aydin et al.   JOURNAL OF CRANIOFACIAL SURGERY

Activation of epiplexus macrophages in hydrocephalus caused by subarachnoid hemorrhage and thrombin

(2019) Yingfeng Wan et al.   CNS Neuroscience & Therapeutics

The senses of the choroid plexus

(2019) C.R.A. Santos et al.   PROGRESS IN NEUROBIOLOGY

DNA methylation signature is prognostic of choroid plexus tumor aggressiveness

(2019) Malgorzata Pienkowska et al.   Clinical Epigenetics

Canine Primary Intracranial Cancer: A Clinicopathologic and Comparative Review of Glioma, Meningioma, and Choroid Plexus Tumors

(2019) Andrew D. Miller et al.   Frontiers in Oncology

Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?

(2019) Marc Desforges et al.   Viruses-Basel

Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease

(2018) Jean-François Ghersi-Egea et al.   ACTA NEUROPATHOLOGICA

Mice Expressing Myc in Neural Precursors Develop Choroid Plexus and Ciliary Body Tumors

(2018) Morgan L. Shannon et al.   AMERICAN JOURNAL OF PATHOLOGY

Age-dependent changes at the blood-brain barrier. A Comparative structural and functional study in young adult and middle aged rats

(2018) Luca Bors et al.   BRAIN RESEARCH BULLETIN

Capsule and fimbriae modulate the invasion of Haemophilus influenzae in a human blood-cerebrospinal fluid barrier model

(2018) Svenja Häuser et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Role of Damage Associated Molecular Pattern Molecules (DAMPs) in Aneurysmal Subarachnoid Hemorrhage (aSAH)

(2018) Shafqat Chaudhry et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glomeruloid Microvascular Proliferation, Desmoplasia, and High Proliferative Index as Potential Indicators of High Grade Canine Choroid Plexus Tumors

(2018) Luisa Vera Muscatello et al.   VETERINARY PATHOLOGY

Cotransporter-mediated water transport underlying cerebrospinal fluid formation

(2018) Annette B. Steffensen et al.   Nature Communications

The Choroid Plexus Functions as a Niche for T-Cell Stimulation Within the Central Nervous System

(2018) Itai Strominger et al.   Frontiers in Immunology

Blood-Cerebrospinal Fluid Barrier Permeability in Alzheimer's Disease

(2018) Sonia Chalbot et al.   JOURNAL OF ALZHEIMERS DISEASE

Choroid plexus-cerebrospinal fluid route for monocyte-derived macrophages after stroke

(2017) Ruimin Ge et al.   Journal of Neuroinflammation

Mitogen-activated protein kinases are required for effective infection of human choroid plexus epithelial cells by Listeria monocytogenes

(2017) Stefanie Dinner et al.   MICROBES AND INFECTION

Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus

(2017) Jason K Karimy et al.   NATURE MEDICINE

Toll-like receptor 4 as a possible therapeutic target for delayed brain injuries after aneurysmal subarachnoid hemorrhage

(2017) Hidenori Suzuki et al.   Neural Regeneration Research

The choroid plexus in health and in disease: dialogues into and out of the brain

(2017) Fernanda Marques et al.   NEUROBIOLOGY OF DISEASE

166 TLR-4-Regulated Cerebrospinal Fluid Hypersecretion in Post-Hemorrhagic Hydrocephalus

(2017) Jason K Karimy et al.   NEUROSURGERY

The effect of melatonin from slow-release implants on basic and TLR-4-mediated gene expression of inflammatory cytokines and their receptors in the choroid plexus in ewes

(2017) M. Kowalewska et al.   RESEARCH IN VETERINARY SCIENCE

Melatonin from slow-release implants did not influence the gene expression of the lipopolysaccharide receptor complex in the choroid plexus of seasonally anoestrous adult ewes subjected or not to a systemic inflammatory stimulus

(2017) M. Kowalewska et al.   SMALL RUMINANT RESEARCH

Sequential transmigration of polymorphonuclear cells and naive CD3 + T lymphocytes across the blood-cerebrospinal-fluid barrier in vitro following infection with Echovirus 30

(2017) Tobias Dahm et al.   VIRUS RESEARCH

Choroid Plexitis and Ependymitis by Magnetic Resonance Imaging are Biomarkers of Neuronal Damage and Inflammation in HIV-negative Cryptococcal Meningoencephalitis

(2017) Dima A. Hammoud et al.   Scientific Reports

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Identification of a novel mechanism of blood–brain communication during peripheral inflammation via choroid plexus‐derived extracellular vesicles

(2016) Sriram Balusu et al.   EMBO Molecular Medicine

Fibrosis of the Choroid Plexus Filtration Membrane

(2016) John W. Prineas et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The Choroid Plexus in Healthy and Diseased Brain

(2016) Charanjit Kaur et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cellular reactions of the choroid plexus induced by peripheral nerve injury

(2016) Marek Joukal et al.   NEUROSCIENCE LETTERS

Cellular uptake of lead in the blood-cerebrospinal fluid barrier: Novel roles of Connexin 43 hemichannel and its down-regulations via Erk phosphorylation

(2016) Han Song et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Type I/II Interferon Balance in the Regulation of Brain Physiology and Pathology

(2016) Aleksandra Deczkowska et al.   TRENDS IN IMMUNOLOGY

E-cadherin, N-cadherin Expression and Histologic Characterization of Canine Choroid Plexus Tumors

(2016) A. Reginato et al.   VETERINARY PATHOLOGY

Uncovering a New Cause of Obstructive Hydrocephalus Following Subarachnoid Hemorrhage: Choroidal Artery Vasospasm–Related Ependymal Cell Degeneration and Aqueductal Stenosis—First Experimental Study

(2016) Coskun Yolas et al.   World Neurosurgery

Transcriptome sequencing of the choroid plexus in schizophrenia

(2016) S Kim et al.   Translational Psychiatry

The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer’s disease

(2015) Sandro Dá Mesquita et al.   BRAIN BEHAVIOR AND IMMUNITY

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

A balanced view of choroid plexus structure and function: Focus on adult humans

(2015) Reynold Spector et al.   EXPERIMENTAL NEUROLOGY

Methemoglobin Is an Endogenous Toll-Like Receptor 4 Ligand—Relevance to Subarachnoid Hemorrhage

(2015) Min Kwon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Brain barriers: Crosstalk between complex tight junctions and adherens junctions

(2015) Silvia Tietz et al.   JOURNAL OF CELL BIOLOGY

Microglia regulate blood clearance in subarachnoid hemorrhage by heme oxygenase-1

(2015) Nils Schallner et al.   JOURNAL OF CLINICAL INVESTIGATION

Leishmania infection and neuroinflammation: Specific chemokine profile and absence of parasites in the brain of naturally-infected dogs

(2015) Guilherme D. Melo et al.   JOURNAL OF NEUROIMMUNOLOGY

Immunization with a Myelin-Derived Antigen Activates the Brain's Choroid Plexus for Recruitment of Immunoregulatory Cells to the CNS and Attenuates Disease Progression in a Mouse Model of ALS

(2015) G. Kunis et al.   JOURNAL OF NEUROSCIENCE

Amyloid   Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases

(2015) M. Brkic et al.   JOURNAL OF NEUROSCIENCE

Soluble Megalin is Reduced in Cerebrospinal Fluid Samples of Alzheimer’s Disease Patients

(2015) Carlos Spuch et al.   Frontiers in Cellular Neuroscience

The choroid plexus—a multi-role player during infectious diseases of the CNS

(2015) Christian Schwerk et al.   Frontiers in Cellular Neuroscience

Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer’s disease

(2015) Ibrahim González-Marrero et al.   Frontiers in Cellular Neuroscience

Parallel Development of Choroid Plexus Degeneration and Meningeal Inflammation in Subarachnoid Hemorrhage – Experimental Study

(2015) Dilcan Kotan et al.   Advances in Clinical and Experimental Medicine

Changes in number of water-filled vesicles of choroid plexus in early and late phase of experimental rabbit subarachnoid hemorrhage model; the role of petrous ganglion of glossopharyngeal nerve

(2014) Mehmet Dumlu Aydin et al.   ACTA NEUROCHIRURGICA

A critical role for pannexin-1 in activation of innate immune cells of the choroid plexus

(2014) Valentyna Maslieieva et al.   Channels

Pathogens Penetrating the Central Nervous System: Infection Pathways and the Cellular and Molecular Mechanisms of Invasion

(2014) Samantha J. Dando et al.   CLINICAL MICROBIOLOGY REVIEWS

Extracellular hemoglobin - mediator of inflammation and cell death in the choroid plexus following preterm intraventricular hemorrhage

(2014) Magnus Gram et al.   Journal of Neuroinflammation

Neisseria meningitidiselicits a pro-inflammatory response involving IκBζ in a human blood-cerebrospinal fluid barrier model

(2014) Julia Borkowski et al.   Journal of Neuroinflammation

Compartmentalized gene expression of toll-like receptors 2, 4 and 9 in the brain and peripheral lymphoid organs during canine visceral leishmaniasis

(2014) G. D. Melo et al.   PARASITE IMMUNOLOGY

IFN-γ-dependent activation of the brain’s choroid plexus for CNS immune surveillance and repair

(2013) Gilad Kunis et al.   BRAIN

Choroid plexus implants rescue Alzheimer’s disease-like pathologies by modulating amyloid-β degradation

(2013) Marta Bolos et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

(2013) Ravid Shechter et al.   IMMUNITY

The surface proteins InlA and InlB are interdependently required for polar basolateral invasion by Listeria monocytogenes in a human model of the blood–cerebrospinal fluid barrier

(2013) Tim Gründler et al.   MICROBES AND INFECTION

Cerebrospinal Fluid Secretion by the Choroid Plexus

(2013) Helle H. Damkier et al.   PHYSIOLOGICAL REVIEWS

Matrix Metalloproteinase-9 Leads to Claudin-5 Degradation via the NF-κB Pathway in BALB/c Mice with Eosinophilic Meningoencephalitis Caused by Angiostrongylus cantonensis

(2013) Ping-Sung Chiu et al.   PLoS One

Interactions between Blood-Borne Streptococcus pneumoniae and the Blood-Brain Barrier Preceding Meningitis

(2013) Federico Iovino et al.   PLoS One

Acute Hydrocephalus After Subarachnoid Hemorrhage—Can It Be Caused by Water Vesicles of Choroid Plexuses?

(2013) Mika Niemelä et al.   World Neurosurgery

Regulation of Toll-Like Receptors in the Choroid Plexus in the Immature Brain After Systemic Inflammatory Stimuli

(2013) Linnea Stridh et al.   Translational Stroke Research

The blood-brain barrier in health and disease

(2012) Richard Daneman   ANNALS OF NEUROLOGY

Opioid Transport by ATP-Binding Cassette Transporters at the Blood-Brain Barrier: Implications for Neuropsychopharmacology

(2012) Nicolas Tournier et al.   CURRENT PHARMACEUTICAL DESIGN

Complexity and developmental changes in the expression pattern of claudins at the blood–CSF barrier

(2012) Ingrid Kratzer et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis

(2012) Jeffrey H Mills et al.   Journal of Neuroinflammation

Matrix Metalloprotease 8-Dependent Extracellular Matrix Cleavage at the Blood-CSF Barrier Contributes to Lethality during Systemic Inflammatory Diseases

(2012) R. E. Vandenbroucke et al.   JOURNAL OF NEUROSCIENCE

Increased aquaporin-1 and Na+-K+-2Cl- cotransporter 1 expression in choroid plexus leads to blood-cerebrospinal fluid barrier disruption and necrosis of hippocampal CA1 cells in acute rat models of hyponatremia

(2012) Jaehyun Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Polar Invasion and Translocation of Neisseria meningitidis and Streptococcus suis in a Novel Human Model of the Blood-Cerebrospinal Fluid Barrier

(2012) Christian Schwerk et al.   PLoS One

Chemotaxis of T-cells after infection of human choroid plexus papilloma cells with Echovirus 30 in an in vitro model of the blood–cerebrospinal fluid barrier

(2012) Henriette Schneider et al.   VIRUS RESEARCH

Cell trafficking through the choroid plexus

(2012) Rick B. Meeker et al.   Cell Adhesion & Migration

Molecular mechanisms of cryptococcal meningitis

(2012) Tong-Bao Liu et al.   Virulence

Passage of parasites across the blood-brain barrier

(2012) Willias Masocha et al.   Virulence

Toward Changing of the Pathophysiologic Basis of Acute Hydrocephalus After Subarachnoid Hemorrhage: A Preliminary Experimental Study

(2012) Ayhan Kanat et al.   World Neurosurgery

A molecular characterization of the choroid plexus and stress-induced gene regulation

(2012) M Sathyanesan et al.   Translational Psychiatry

Pathological Alteration in the Choroid Plexus of Alzheimer’s Disease: Implication for New Therapy Approaches

(2012) Agnieszka Krzyzanowska et al.   Frontiers in Pharmacology

Molecular heterogeneity in the choroid plexus epithelium: the 22-member γ-protocadherin family is differentially expressed, apically localized, and implicated in CSF regulation

(2011) Mark A. Lobas et al.   JOURNAL OF NEUROCHEMISTRY

Transcellular migration of neutrophil granulocytes through the blood-cerebrospinal fluid barrier after infection with Streptococcus suis

(2011) Corinna Wewer et al.   Journal of Neuroinflammation

Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration

(2011) Jacque PK Ip et al.   Journal of Neuroinflammation

Aberrant E-cadherin, β-catenin, and glial fibrillary acidic protein (GFAP) expression in canine choroid plexus tumors

(2011) Alice Nentwig et al.   JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION

In vitro transcriptome analysis of porcine choroid plexus epithelial cells in response to Streptococcus suis: release of pro-inflammatory cytokines and chemokines

(2011) Christian Schwerk et al.   MICROBES AND INFECTION

The Immunopathophysiology of Multiple Sclerosis

(2011) Gregory F. Wu et al.   NEUROLOGIC CLINICS

The effect of choroidal artery vasospasm on choroid plexus injury in subarachnoid hemorrhage: experimental study

(2011) Adem Yilmaz et al.   Turkish Neurosurgery

Inflammation of the Choroid Plexus and Ependymal Layer of the Ventricle Following Intraventricular Hemorrhage

(2011) Philippe F. Simard et al.   Translational Stroke Research

Anatomy and physiology of cerebrospinal fluid

(2011) L. Sakka et al.   European Annals of Otorhinolaryngology-Head and Neck Diseases

Cerebrolysin reduces blood-cerebrospinal fluid barrier permeability change, brain pathology, and functional deficits following traumatic brain injury in the rat

(2010) Hari Shanker Sharma et al.   Annals of the New York Academy of Sciences

Cryptococcal choroid plexitis: rare imaging findings of central nervous system cryptococcal infection in an immunocompetent individual

(2010) R Kumari et al.   BRITISH JOURNAL OF RADIOLOGY

TNF Induces Choroid Plexus Epithelial Cell Barrier Alterations by Apoptotic and Nonapoptotic Mechanisms

(2010) Christian Schwerk et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Role of CCL2 (MCP-1) in Traumatic Brain Injury (TBI): Evidence from Severe TBI Patients and CCL2−/− Mice

(2010) Bridgette D Semple et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Cytokine Response to Human Traumatic Brain Injury: Temporal Profiles and Evidence for Cerebral Parenchymal Production

(2010) Adel Helmy et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Increased Plasma and Tissue MMP Levels are Associated with BCSFB and BBB Disruption Evident on Post-Contrast FLAIR after Experimental Stroke

(2010) Ayush Batra et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Trafficking of immune cells in the central nervous system

(2010) Emma H. Wilson et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation and role of organic anion-transporting polypeptides (OATPs) in drug delivery at the choroid plexus

(2010) Hao Zhang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Traumatic brain injury and recovery mechanisms: peptide modulation of periventricular neurogenic regions by the choroid plexus–CSF nexus

(2010) Conrad Johanson et al.   JOURNAL OF NEURAL TRANSMISSION

A Novel Population of Myeloid Cells Responding to Coxsackievirus Infection Assists in the Dissemination of Virus within the Neonatal CNS

(2010) J. M. Tabor-Godwin et al.   JOURNAL OF NEUROSCIENCE

Neuromyelitis optica: a demyelinating disease characterized by acute destruction and regeneration of perivascular astrocytes

(2010) John DE Parratt et al.   Multiple Sclerosis Journal

The emerging role of microRNAs in multiple sclerosis

(2010) Andreas Junker et al.   Nature Reviews Neurology

Time-dependent contribution of non neuronal cells to BDNF production after ischemic stroke in rats

(2010) Yannick Béjot et al.   NEUROCHEMISTRY INTERNATIONAL

Protective effect of albumin on VEGF and brain edema in acute ischemia in rats

(2010) Xiaomei Yao et al.   NEUROSCIENCE LETTERS

The Distributional Nexus of Choroid Plexus to Cerebrospinal Fluid, Ependyma and Brain

(2010) Conrad Johanson et al.   TOXICOLOGIC PATHOLOGY

Immunohistochemical Characterization of Canine Neuroepithelial Tumors

(2010) T. Ide et al.   VETERINARY PATHOLOGY

Oxidative stress damage and oxidative stress responses in the choroid plexus in Alzheimer’s disease

(2009) Ester Perez-Gracia et al.   ACTA NEUROPATHOLOGICA

Choroid plexus: biology and pathology

(2009) Hartwig Wolburg et al.   ACTA NEUROPATHOLOGICA

Choroid Plexus Connexin 43 Expression and Gap Junction Flexibility Are Associated with Clinical Features of Acute EAE

(2009) K. Jovanova-Nesic et al.   Annals of the New York Academy of Sciences

Incidence of bacterial meningitis (2001–2005) in Lazio, Italy: the results of a integrated surveillance system

(2009) Paolo Giorgi Rossi et al.   BMC INFECTIOUS DISEASES

The choroid plexus response to a repeated peripheral inflammatory stimulus

(2009) Fernanda Marques et al.   BMC NEUROSCIENCE

TWIST-1 Is Overexpressed in Neoplastic Choroid Plexus Epithelial Cells and Promotes Proliferation and Invasion

(2009) M. Hasselblatt et al.   CANCER RESEARCH

Listeria monocytogenesinternalin and E-cadherin: from structure to pathogenesis

(2009) Matteo Bonazzi et al.   CELLULAR MICROBIOLOGY

Clearance of Amyloid-β Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimers Disease

(2009) R. Deane et al.   CNS & Neurological Disorders-Drug Targets

Altered Iron Metabolism Is Part of the Choroid Plexus Response to Peripheral Inflammation

(2009) F. Marques et al.   ENDOCRINOLOGY

The Role of the Choroid Plexus in Neutrophil Invasion after Traumatic Brain Injury

(2009) Joanna Szmydynger-Chodobska et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Kinetic Profile of the Transcriptome Changes Induced in the Choroid Plexus by Peripheral Inflammation

(2009) Fernanda Marques et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Transplantation of cultured choroid plexus epithelial cells via cerebrospinal fluid shows prominent neuroprotective effects against acute ischemic brain injury in the rat

(2009) Naoya Matsumoto et al.   NEUROSCIENCE LETTERS

The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction

(2009) Britta Engelhardt et al.   Seminars in Immunopathology

Involvement of NF-κB and MAP-kinases in the transcriptional response of alveolar macrophages to Streptococcus suis

(2009) Astrid de Greeff et al.   VETERINARY MICROBIOLOGY

Delivery of peptides to the brain: Emphasis on therapeutic development

(2008) William A. Banks   BIOPOLYMERS

Dexamethasone prevents alteration of tight junction-associated proteins and barrier function in porcine choroid plexus epithelial cells after infection with Streptococcus suis in vitro

(2008) Tobias Tenenbaum et al.   BRAIN RESEARCH

TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme

(2008) L. Verstrepen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Polar bacterial invasion and translocation ofStreptococcus suisacross the blood-cerebrospinal fluid barrierin vitro

(2008) Tobias Tenenbaum et al.   CELLULAR MICROBIOLOGY

Involvement of the choroid plexus in multiple sclerosis autoimmune inflammation: A neuropathological study

(2008) Marco Vercellino et al.   JOURNAL OF NEUROIMMUNOLOGY

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Vascular Endothelial Growth Factor and Nitric Oxide Production in Response to Hypoxia in the Choroid Plexus in Neonatal Brain

(2007) Viswanathan Sivakumar et al.   BRAIN PATHOLOGY

Primary high-grade B-cell lymphoma of the choroid plexus

(2007) Paolo C. Cecchi et al.   CLINICAL NEUROLOGY AND NEUROSURGERY