Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing

Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer

(2020) Pranabananda Dutta et al.   BMC CANCER

Self DNA perpetuates IPF lung fibroblast senescence in a cGAS-dependent manner

(2020) Michael Schuliga et al.   CLINICAL SCIENCE

STAT3 Regulates the Onset of Oxidant-Induced Senescence in Lung Fibroblasts

(2019) David W Waters et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Hallmarks of senescence and aging

(2019) Slavica Dodig et al.   Biochemia Medica

Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis

(2018) David W Waters et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The senescent bystander effect is caused by ROS-activated NF-κB signalling

(2018) Glyn Nelson et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Hallmarks of Cellular Senescence

(2018) Alejandra Hernandez-Segura et al.   TRENDS IN CELL BIOLOGY

Targeting Senescent Cells in Fibrosis: Pathology, Paradox, and Practical Considerations

(2018) Marissa J. Schafer et al.   Current Rheumatology Reports

Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts

(2018) Michael Schuliga et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosisex vivo

(2017) Mareike Lehmann et al.   EUROPEAN RESPIRATORY JOURNAL

Cellular senescence mediates fibrotic pulmonary disease

(2017) Marissa J. Schafer et al.   Nature Communications

Idiopathic pulmonary fibrosis

(2017) Fernando J. Martinez et al.   Nature Reviews Disease Primers

Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients

(2015) Hagai Yanai et al.   Aging-US

Management of Idiopathic Pulmonary Fibrosis in the Elderly Patient

(2015) Keith C. Meyer et al.   CHEST

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

(2013) Juan Carlos Acosta et al.   NATURE CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The pathogenesis of COPD and IPF: Distinct horns of the same devil?

(2012) Marco Chilosi et al.   RESPIRATORY RESEARCH

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

(2010) Joon-Il Jun et al.   NATURE CELL BIOLOGY

Targeted Injury of Type II Alveolar Epithelial Cells Induces Pulmonary Fibrosis

(2009) Thomas H. Sisson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SASP reflects senescence

(2009) Andrew R J Young et al.   EMBO REPORTS

WNT1-inducible signaling protein–1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis

(2009) Melanie Königshoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY